Point-of-care SERS platforms: integrating microfluidics and machine learning for disease screening [0.03%]
集成了微流控和机器学习的现场拉曼检测平台用于疾病筛查
Biqing Chen,Xiaohong Qiu,Yang Li
Biqing Chen
With the continuous advancement of research on life systems and disease mechanisms, analytical technologies are now moving toward the resolution of single molecules and individual genes. Among them, surface-enhanced Raman scattering (SERS) ...
Development of a 16-channel solid-state nanopore array platform for integrated nanopore fabrication and ionic current measurement [0.03%]
一种用于集成纳米孔制造和离子电流测量的16通道固态纳米孔阵列平台的发展
Itaru Yanagi,Tadashi Kiyuna,Keiko Esashika et al.
Itaru Yanagi et al.
Parallel solid-state nanopore measurements are expected to improve not only throughput but also molecular discrimination performance. Here, we report the development of a 16-channel solid-state nanopore array measurement system that enables...
Highly sensitive wireless dual-spiral resonant contact lens for continuous intraocular pressure monitoring [0.03%]
一种高灵敏度的无线双螺旋共振隐形眼镜连续监测眼内压
Ying Liu,Zhixian Chen,Xiaoyu Zhao et al.
Ying Liu et al.
Continuous and non-invasive intraocular pressure (IOP) monitoring is crucial for managing glaucoma, a leading cause of irreversible blindness worldwide. However, existing tonometry methods are intermittent and lack the capability to capture...
Microfluidic profiling of suspension cell-metal adhesion at single-cell resolution under flow [0.03%]
基于流动的单细胞分辨率悬浮细胞-金属粘附微流体分析方法研究
Eunyoung Park,Seungjin Kang,Jieung Oh et al.
Eunyoung Park et al.
Metallic implants used in vascular applications must maintain functionality under dynamic blood flow conditions. A critical factor affecting their performance is the unintended adhesion of blood cells, including red blood cells (RBCs), to t...
Yield stress fluids in microfluidics: research, applications and opportunities [0.03%]
微流控中的屈服应力流体：研究、应用及机遇
Hossein Rahmani,Seyed Mohammad Taghavi
Hossein Rahmani
Microfluidic technology enables scalable solutions in precision medicine, diagnostics, drug delivery, organ-on-a-chip models, single-cell analysis, high-throughput screening, and environmental monitoring. In fact, many of these applications...
A portable modular acoustic streaming vortex platform for flexible and robust fabrication of monodisperse micromaterials [0.03%]
一种便携式模块化声流涡旋平台用于制备单分散微米材料
Xiaoping Miao,Tianao Chen,Jijie Fu et al.
Xiaoping Miao et al.
Droplet microfluidics is indispensable for precision fabrication of microscale functional materials, with broad applications in biomedical engineering, flexible electronics, and materials science. However, conventional microchannel-based sy...
A novel 3D-printed tool for in vitro cell interaction studies under flow conditions [0.03%]
一种新型的3D打印工具用于体外流动条件下的细胞相互作用研究
Katharina Skoll,Maria Zobl,Elke Heiss et al.
Katharina Skoll et al.
The interaction of drug formulations with cells is a critical factor in the development of effective therapeutics. Conventional in vitro models, such as static horizontal monolayer cultures, often fail to account for key parameters such as ...
Automation-assisted human skin-on-a-chip for modeling ultraviolet-induced injury and evaluating photoprotective and regenerative modalities [0.03%]
自动化辅助的人工皮肤芯片技术，用于模拟紫外线伤害及评估光防护和再生方法
Yu-Jeong Lee,Jieun Lee,Yoojin Na et al.
Yu-Jeong Lee et al.
Ultraviolet B (UVB) irradiation is a major cause of acute skin damage and photoaging; however, human-relevant in vitro platforms for systematic evaluation of photoprotective and regenerative strategies are limited. Increasing demands for re...
Thin stencil membrane-assisted high throughput single-cell to cluster of cells micropatterning and large-size biomolecular transfection in primary and stem cells [0.03%]
用于干细胞和原代细胞的大尺寸生物大分子转染及单细胞至细胞团的高通量微图案技术
Donia Dominic,Srabani Kar,Rajdeep Ojha et al.
Donia Dominic et al.
Precise control of cellular organization and intracellular delivery is essential for bioengineering and therapeutic applications. We present an integrated platform that combines cell micropatterning using PDMS stencil membranes with a micro...
Multiplexed nanophotonic biosensing and deep learning-driven protein quantification for traumatic brain injury diagnosis at the point of care [0.03%]
用于创伤性脑损伤诊断的复用纳米光子生物传感和深度学习驱动的蛋白质定量(point-of-care traumatic brain injury diagnosis)
Jiayu Liu,Yuxin Wang,Shichao Su et al.
Jiayu Liu et al.
Traumatic brain injury (TBI) triage and monitoring demand rapid, sensitive, and deployable biomarker assays. We present an AI-integrated nanophotonic biosensor enabling ultrasensitive multiplexed quantification of S100B, GFAP, and UCH-L1 ac...