Two-phase simulations of viscoplastic flow in superhydrophobic microchannels: interface stability, plug dynamics, and drag reduction [0.03%]
超疏水微通道中粘塑性流体的两相模拟：界面稳定性、塞流动力学和摩擦力减阻效应
Amir Joulaei,Hossein Rahmani,Seyed Mohammad Taghavi
Amir Joulaei
Superhydrophobic surfaces are widely investigated in microfluidics for drag reduction; however, their role in transporting viscoplastic biological fluids such as blood, mucus, and hydrogels remains poorly understood. Here, high-resolution t...
A smart 3D microfluidic tumor spheroid-vessel co-culture model for studying exosomal HSP-mediated tumor invasion and angiogenesis [0.03%]
一种智能的三维微流体肿瘤类球-血管共培养模型用于研究热休克蛋白介导的肿瘤侵袭和血管生成中的外泌体作用机制
Sisi Zhou,Fanshu Shan,Yue Zhang et al.
Sisi Zhou et al.
Breast cancer is one of the most prevalent malignant tumors in women, primarily due to their metastasis and recurrence. Deciphering the molecular mechanisms underlying breast cancer metastasis and recurrence remains a major challenge. Herei...
MaGIC-OT: an AI-guided optical tweezers platform for autonomous single-cell isolation in microfluidic devices [0.03%]
一种基于人工智能的光学镊子平台，可在微流体装置中实现单细胞自动分离
Jan-Philipp Cieslik,Xiaoye Xia,Ali Salehi-Reyhani
Jan-Philipp Cieslik
Automating the isolation of rare cells such as circulating tumour cells (CTCs) within crowded microfluidic environments remains a bottleneck in liquid biopsy workflows. Optical tweezers offer contact-free, selective manipulation but traditi...
A wearable 3D-printed hollow microneedle device for pressure-driven interstitial fluid collection and testing [0.03%]
一种用于压力驱动的间质液采集和检测的可穿戴3D打印中空微针装置
Nedim Hacıosmanoğlu,Emre Ece,Fatih Inci
Nedim Hacıosmanoğlu
Interstitial fluid (ISF) is the extracellular fluid within the dermis that transports biomolecules diffusing from blood vessels to lymphatic vessels. Owing to its blood-like composition and accessibility only a few millimeters beneath the s...
Twenty years of microfluidic probes and open-space microfluidics: from origins to emerging directions [0.03%]
微流控探针和开放空间微流控的二十年：从起源到新兴方向
Dima Samer Ali,Ayoub Glia,Mohammad A Qasaimeh
Dima Samer Ali
Microfluidic probes (MFPs) are an emerging class of open microfluidic devices that use hydrodynamic flow confinement (HFC) to enable precise, contact-free delivery, and removal of fluids on biological surfaces. Unlike closed-channel microfl...
MyeliMAP: a microfluidic-multielectrode array hybrid platform to investigate oligodendrocyte function in human iPSC derived brain-like networks [0.03%]
我的MyeliMAP：一个用于研究人类iPSC来源的脑类器官中少突胶质细胞功能的微流控-多电极阵列混合平台
Karan Ahuja,Blandine F Clément,Giulia Amos et al.
Karan Ahuja et al.
Oligodendrocytes are the myelinating glia of the central nervous system (CNS), essential for rapid signal propagation, metabolic support, and neuronal health. While rodent-based cultures and organoid systems have provided insights into olig...
Systematic characterization and mechanistic insights into ultrasonically actuated sharp-tip capillary droplet generation [0.03%]
超声波尖端毛细管液滴生成的系统表征及机理研究
Qi Zhang,Li Ran,Gang Li
Qi Zhang
Ultrasonically actuated sharp-tip capillary droplet generation offers a chip-free approach to produce microdroplets for applications such as micro-/nanoparticle synthesis and biochemical analysis, eliminating the need for complex microfluid...
Label-free assessment of a microfluidic vessel-on-chip model with visible-light optical tomography reveals structural changes in vascular networks [0.03%]
基于可见光光学层析的无标记血管片上模型评估发现血管网络结构变化
Devin Veerman,Carlos Cuartas-Vélez,Tarek Gensheimer et al.
Devin Veerman et al.
Microvascular dysfunction is characterized by impaired structure and function of small blood vessels, contributing to disease-related tissue and organ damage, such as in the retina. Optical coherence tomography is a widely used clinical tec...
Elham Akbari,Jason P Beech,Johannes Kumra Ahnlide et al.
Elham Akbari et al.
Group A Streptococcus (GAS) forms highly deformable aggregates with broad variations in size and morphology, complicating controlled separation and biological analysis. Reliable methods to isolate fractions of GAS clusters with defined prop...
Nanofluidic-based electrochemical pump for remotely controlled, on-demand drug delivery [0.03%]
一种基于纳米流体的电化学泵，用于远程控制按需给药
Marco M Paci,Nicola Di Trani,Paolo Bolla et al.
Marco M Paci et al.
Implantable drug delivery systems offer the promise of on-demand, tunable release profiles tailored to individual therapeutic needs. Here, we present a nanofluidic membrane-based electrochemical delivery system that leverages controlled in ...