Real-time impedance-based cell migration measurements with integrated electrodes on porous membranes for next generation microphysiological systems [0.03%]
基于阻抗的实时细胞迁移测量集成电极在多孔膜上的用于下一代微生理系统中的细胞迁移测量
Karina Torres-Castro,Aditya Rane,Darwin R Reyes
Karina Torres-Castro
We present a novel microfluidic device capable of electrically interrogating both surfaces of a porous membrane quantitatively and in real time using electrical impedance spectroscopy to monitor cell migration. This device holds patterned g...
Xian Chen,Chuanchao Zhang,Yaping Wang et al.
Xian Chen et al.
Micro-mixing plays an important role in biochemical analyses using miniaturized total analysis systems (μTASs) or lab-on-chips. However, existing micromixers primarily rely on a specific medium and lack the capability of being activated on...
Inkube: an all-in-one solution for neuron culturing, electrophysiology, and fluidic exchange [0.03%]
Inkube：用于神经元培养、电生理和流体交换的一站式解决方案
Benedikt Maurer,Selina Fassbind,Tobias Ruff et al.
Benedikt Maurer et al.
Culturing neuronal networks in vitro is a tedious and time-consuming endeavor. In addition, how the composition of the culture medium and environmental variables such as temperature, osmolarity, and pH affect the spiking behavior of neurona...
Leyla Akh,Apresio K Fajrial,Sunwoo Sohn et al.
Leyla Akh et al.
Genetic engineering of cells has a range of applications in treating incurable diseases. Plasmid DNA is a popular choice of nucleic acid for cell engineering due to its low cost and stability. However, plasmid DNA must survive the protectiv...
Hydrogel microwell with pneumatic soft actuator for compression formation of three-dimensional cellular tissue [0.03%]
用于三维细胞组织压缩成型的气动软执行器水凝胶微井
Ryota Kawamae,Atsushi Takata,Kenjiro Takemura et al.
Ryota Kawamae et al.
Three-dimensional cellular tissue reproduces the structure and function similar to the tissues in the body. So far, as a means for the formation and maturation of three-dimensional cellular tissues, various mechanical stimuli have been appl...
A portable, low-cost, point-of-care DNA amplification kit with impedance-based detection for decentralized antimicrobial resistance diagnostics [0.03%]
一种便于携带、低成本的基于阻抗检测的便携式DNA扩增试剂盒用于分散式的抗菌素耐药性诊断
Koosha Karimi,Miriam Arroyo,Erin E Chille et al.
Koosha Karimi et al.
This study introduces a low-cost, portable DNA amplification kit that performs a modified loop-mediated isothermal amplification (LAMP) reaction, which produces DNA nanoballs and combines it with a previously developed microfluidic impedanc...
Bianca Menzani,Priscille De Gea,Xavier Gidrol et al.
Bianca Menzani et al.
Organoids represent one of the most advanced in vitro models for studying human physiology, development and disease. Their potential is very important and they have broad applications, but their impact is currently limited by persistent cha...
Intelligent image-activated sorting of large cells enabled by elasto-inertial focusing [0.03%]
一种基于弹性惯性聚焦的大细胞智能图像激活分选方法
Yuzuki Nagasaka,Akihiro Isozaki,Hiroki Matsumura et al.
Yuzuki Nagasaka et al.
Image-activated cell sorting (IACS) enables high-speed sorting of cells based on real-time analysis of their images, providing a powerful means to link cellular morphology and function at the single-cell level on a large scale. Although IAC...
Progress toward real-world diagnostic applications of microfluidic paper-based analytical devices (μPADs) [0.03%]
基于纸张的微流体分析器件(μPAD)在实际诊断应用中的进展
Yohei Tanifuji,Daniel Citterio
Yohei Tanifuji
Since their first report in 2007, microfluidic paper-based analytical devices (μPADs) have continued to gain attention as promising tools for point-of-care diagnostics due to their low cost, portability, ease of operation, and design flexi...
WAFFLE - an automated platform for enhancing the performance of electrochemical biosensors [0.03%]
WAFFLE——一种用于提升电化学生物传感器性能的自动化平台
Alexandra Dobrea,Rowan Blake,Daniel Macdonald et al.
Alexandra Dobrea et al.
Electrochemical biosensors and microfluidics have an inherently synergistic relationship which can allow unparalleled levels of signal enhancement, automation and scalability. In spite of this, the full advantages of fluidic automation rema...