Seemesh Bhaskar,Saurabh Umrao,Han Keun Lee et al.
Seemesh Bhaskar et al.
Cancer remains one of the leading global health burdens, demanding swift, precise, and accessible diagnostic responses that can overcome the limitations of diagnostic tests performed in centralized laboratory settings. Point-of-care (POC) m...
Dual vision-equipped microfluidic chip for spatiotemporal sequential pick-and-place of oocytes [0.03%]
一种用于时空顺序抓取和放置卵母细胞的双视觉微流控芯片
Shuzhang Liang,Hao Mo,Yuguo Dai et al.
Shuzhang Liang et al.
Oocytes have long been used as a fundamental biological model in bioengineering research such as gene expression analysis, electrophysiological measurements, and drug screening. However, current methods mainly focus on single-microscope set...
High-throughput and efficient fabrication of engineered skeletal muscle tissue via streamlined 3D multimaterial bioprinting [0.03%]
通过连续的三维多材料生物打印高效地工程化骨骼肌组织
Tae-Eun Lim,Ashfaq Ahmad,Yeong-Jin Choi et al.
Tae-Eun Lim et al.
Skeletal muscle diseases have led to an increasing need for a range of physiologically relevant organ-on-a-chip and three-dimensional (3D) culture platforms owing to their clinical significance and ongoing efforts to develop effective thera...
3D ECM-inflammation model on a microfluidic chip for neutrophil transmigration from whole blood investigations [0.03%]
用于全血中性粒细胞迁移研究的微流控芯片上的三维ECM-炎症模型
Shide Bakhtiari,Vanessa Velasco,Ronald W Davis
Shide Bakhtiari
Neutrophils have been linked to several inflammation diseases. To study the role of neutrophils in inflammation diseases and conditions, in vitro inflammation assays have been developed. Two drawbacks of these assays include the reliance on...
High-throughput single-cell proteomics and transcriptomics from same cells with a nanoliter-scale, spin-transfer approach [0.03%]
一种纳升级离心转接方法可对同一细胞进行高通量单细胞蛋白质组学和转录组学分析
Pranav Dawar,Lye Meng Markillie,Sarah M Williams et al.
Pranav Dawar et al.
Single-cell multiomic platforms provide a comprehensive snapshot of cellular states and cell types by offering critical insights into the spatiotemporal regulation of biomolecular networks at a systems level, thereby defining the basis of m...
Gabrielle Saint-Girons,Kaustav A Gopinathan,Sajad Razavi Bazaz et al.
Gabrielle Saint-Girons et al.
Although several contact-free trapping techniques exist in microfluidics - such as optical, acoustic, and dielectrophoretic - these approaches often face tradeoffs including: limited area, fine tuning, or special buffers. Here, we introduce...
Integrated strategy for breast cancer biomarker analysis using dual ionic liquid aqueous biphasic systems and microfluidic immunoassays [0.03%]
基于双离子液体水两相体系和微流控免疫测定的乳腺癌生物标志物分析集成策略
Maria S M Mendes,Inês Agostinho,Maria C Souza et al.
Maria S M Mendes et al.
Human epidermal growth factor receptor 2 (HER2) is a key biomarker in breast cancer diagnosis, prognosis, and therapeutic decision-making. While its determination is traditionally based on tissue biopsy, serum-based testing is a simpler and...
Integrated microfluidic platform based on potentiometric Sonogel-Carbon sensors for the simultaneous determination of Na+ and K+ in untreated human plasma and serum [0.03%]
基于Potentiometric Sonogel-碳传感器的集成微流控平台同时测定人血浆和血清中的Na+和K+
Álvaro Jesús Sainz-Calvo,Álvaro Cordero-Hernández,Marina Jiménez-Rodríguez et al.
Álvaro Jesús Sainz-Calvo et al.
In the present work, two potentiometric sensors for the simultaneous determination of sodium and potassium ions were successfully developed. A novel functionalized multi-walled carbon nanotube sonogel-based mixture served as ion-to-electron...
Dissociable perfusion chip (DPC): perfusable microfluidic chip for single-cell screening of anti-cancer drugs in live glioblastoma explants [0.03%]
可分离灌注芯片（DPC）：活胶质母细胞瘤标本中单细胞抗肿瘤药物筛选的灌注型微流控芯片
Darragh G Kennedy,Wenting Zhao,Terry L Chern et al.
Darragh G Kennedy et al.
New approaches are needed to screen anti-cancer drugs that can target specific subpopulations of tumor cells. This study presents a microfluidic chip that enables parallel culture and drug perturbation of five thick tissue slices from human...
Macroporous transport - mesoporous catalysis: a rapid microfluidic-fabricated biomimetic sponge photocatalytic microsphere reactor [0.03%]
宏观输运-介观催化：一种快速微流控制造的仿生海绵光催化微球反应器
Qikai Wang,Wenwen Shi,Qihang Yang et al.
Qikai Wang et al.
To address the low light-harvesting efficiency, rapid charge recombination, and restricted mass transport in conventional photocatalysts, this study proposes a bio-inspired SiO2@TiO2 photocatalytic microsphere reactor (ST-PCMR), rapidly fab...