Medical Cannabis Use in France: An Observational Safety Study Based on the RECANN Registry and the Pharmacovigilance/Addictovigilance System From 2021 to 2024 [0.03%]
2021至2024年基于RECANN登记册和药物警戒/成瘾监测系统的法国医疗用大麻使用观察性安全性研究
Cécile Chevallier,Anne Batisse,Emilie Monzon et al.
Cécile Chevallier et al.
Introduction: The French National Agency for Medicines and Health Products Safety implemented in 2021 a nationwide experimentation for medical cannabis (MC), designed to assess the feasibility of implementing a new public...
Observational Study
Fundamental & clinical pharmacology. 2026 Mar;40(2):e70074. DOI:10.1111/fcp.70074 2026
Immunomodulatory Effects of Hyoscine Butylbromide on Mammalian Macrophages [0.03%]
溴化丁基东莨菪碱对哺乳动物巨噬细胞的免疫调节作用
Begüm Rana Atalay,Batuhan Yurtseven,Ebru Akbaba et al.
Begüm Rana Atalay et al.
Hyoscine butylbromide (HB), popularly known as Buscopan, is a common anticholinergic antispasmodic used worldwide for gastrointestinal disorders. While the interaction between the cholinergic system and immunity is increasingly recognized, ...
SGLT-2 Inhibitors Use in Hospitalized Patients in France: A Cross-Sectional Study [0.03%]
法国住院患者使用SGLT-2抑制剂的现状：一项横断面研究
Maxime Demourgues,Julien Bezin,Romain Griffier et al.
Maxime Demourgues et al.
Background: Sodium glucose co-transporter type 2 inhibitors (SGLT2i) were initially developed as glucose-lowering drugs for diabetic patients. A few years after their market authorization in Europe, their indications were...
Blandine Bertin,Valentine Lacotte,Jean-Luc Cracowski et al.
Blandine Bertin et al.
Background: Statin-induced liver injury is frequent and usually not severe. The aim of the present study was to describe the safety of statin rechallenge after atorvastatin-induced liver injury because it is poorly docume...
Real-World Use of Dupilumab in Atopic Dermatitis: Observational Study Results Linked to SNDS [0.03%]
杜普利尤单抗治疗特应性皮炎的真实世界使用情况：与国家药品数据库系统相连接的观察性研究结果
Alain Dupuy,Anne-Claire Fougerousse,Pierre-André Bécherel et al.
Alain Dupuy et al.
Background: Dupilumab is reimbursed in France for adult patients with moderate-to-severe atopic dermatitis (AD), in cases of failure, intolerance or contraindication to cyclosporin A (CsA). The French National Authority f...
Observational Study
Fundamental & clinical pharmacology. 2026 Mar;40(2):e70070. DOI:10.1111/fcp.70070 2026
JAK Inhibitors and Memory Impairment: Disproportionality Analyses in the WHO Global Pharmacovigilance Database, VigiBase [0.03%]
全球药监数据库VigiBase中Janus激酶抑制剂与记忆损害的 disproportionality 分析
Marilou Duboëlle,Adriano Lercara,Yves-Marie Pers et al.
Marilou Duboëlle et al.
Background: Chronic inflammation is involved in various mechanisms of memory impairment (MI). Although Janus kinase inhibitors (JAKi), which inhibit cytokine-induced JAK-STAT pathway, could theoretically protect against M...
Correction to "Topical Probiotic Therapy Reduces Chemotherapy-Induced Oral Mucositis: Preclinical Evaluation in a Rat Model" [0.03%]
“ topical probiotic therapy reduces chemotherapy-induced oral mucositis : preclinical evaluation in a rat model”的勘误通知书
Published Erratum
Fundamental & clinical pharmacology. 2026;40(1):e20017. DOI:10.1111/fcp.70071 2026
French-Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics [0.03%]
法国药理基因组学网络(RNPGx)关于通过基因分型或测序进行药理基因组学基因检测的建议
Nicolas Picard,Estelle Ayme-Dietrich,Sylvie Quaranta et al.
Nicolas Picard et al.
Background: The implementation of pharmacogenetics in clinical practice increasingly relies on multigene panels. Objectives: The object...
The Hill-Langmuir Equation Governs Drug-Target Binding Kinetics for Pulsed Drug Delivery [0.03%]
脉冲给药方式下的药物靶向结合动力学服从希尔-朗缪尔方程
Xiaomin Shi
Xiaomin Shi
Background: Receptor occupancy is an important indicator of drug efficacy. Pulsed drug delivery is aimed at accurately determining the dosing time on the basis of the onset rhythm. ...
Use of Psychoactive Substances Before Incarceration Among Prison Inmates With Drug Abuse or Dependence: Data From the OPPIDUM Program [0.03%]
来自OPPIDUM项目的数据：监狱中具有药物滥用或依赖问题的囚犯在入狱前使用精神活性物质的情况
Zeinab Abbas,Clémence Lacroix,Elisabeth Jouve et al.
Zeinab Abbas et al.
Background: The objective of this study was to assess the prevalence of dependence and abuse of psychoactive substances (PAS) among prison inmates, using data from the OPPIDUM program between 2013 and 2022. ...