Redundant trials can be prevented, if the EU clinical trial regulation is applied duly [0.03%]
只要操作得当,《欧盟临床试验条例》可以预防重复试验
Daria Kim,Joerg Hasford
Daria Kim
The problem of wasteful clinical trials has been debated relentlessly in the medical community. To a significant extent, it is attributed to redundant trials - studies that are carried out to address questions, which can be answered satisfa...
Ethics and the marketing authorization of pharmaceuticals: what happens to ethical issues discovered post-trial and pre-marketing authorization? [0.03%]
药物市场准入的伦理问题:如何处理临床试验后和获批上市前发现的新的伦理问题?
Rosemarie D L C Bernabe,Ghislaine J M W van Thiel,Nancy S Breekveldt et al.
Rosemarie D L C Bernabe et al.
Background: In the EU, clinical assessors, rapporteurs and the Committee for Medicinal Products for Human Use are obliged to assess the ethical aspects of a clinical development program and include major ethical flaws in ...
An ethical issue: nurses' conscientious objection regarding induced abortion in South Korea [0.03%]
一个伦理问题:南韩护士对于人工流产的良心拒绝问题
Chung Mee Ko,Chin Kang Koh,Ye Sol Lee
Chung Mee Ko
Background: The Constitutional Court of South Korea declared that an abortion ban was unconstitutional on April 11, 2019. The National Health Care System will provide abortion care across the country as a formal medical s...
"It gets people through the door": a qualitative case study of the use of incentives in the care of people at risk or living with HIV in British Columbia, Canada [0.03%]
“它能吸引人们进门”:英属哥伦比亚HIV感染风险人群或HIV感染者医疗保障中奖励使用的质性案例研究
Marilou Gagnon,Adrian Guta,Ross Upshur et al.
Marilou Gagnon et al.
Background: There has been growing interest in the use of incentives to increase the uptake of health-related behaviours and achieve desired health outcomes at the individual and population level. However, the use of ince...
The relationship between the perception of open disclosure of patient safety incidents, perception of patient safety culture, and ethical awareness in nurses [0.03%]
护士对患者安全事件开放披露认知、患者安全文化感知及伦理意识的关系研究
Yujeong Kim,Eunmi Lee
Yujeong Kim
Background: Scientific advances have resulted in more complex medical systems, which in turn have led to an increase in the number of patient safety incidents (PSIs). In this environment, the importance of honest disclosu...
A qualitative study of big data and the opioid epidemic: recommendations for data governance [0.03%]
大数据与阿片类药物泛滥的定性研究:对数据治理的建议
Elizabeth A Evans,Elizabeth Delorme,Karl Cyr et al.
Elizabeth A Evans et al.
Background: The opioid epidemic has enabled rapid and unsurpassed use of big data on people with opioid use disorder to design initiatives to battle the public health crisis, generally without adequate input from impacted...
Genetic testing for breast cancer risk, from BRCA1/2 to a seven gene panel: an ethical analysis [0.03%]
从BRCA1 / 2到七基因面板的乳腺癌风险的基因检测:伦理分析
Erik Gustavsson,Giovanni Galvis,Niklas Juth
Erik Gustavsson
Background: Genetic testing is moving from targeted investigations of monogenetic diseases to broader testing that may provide more information. For example, recent health economic studies of genetic testing for an increa...
Potential research ethics violations against an indigenous tribe in Ecuador: a mixed methods approach [0.03%]
对厄瓜多尔土著部落潜在的研究伦理侵犯:混合研究方法
Esteban Ortiz-Prado,Katherine Simbaña-Rivera,Lenin Gómez-Barreno et al.
Esteban Ortiz-Prado et al.
Background: Biomedical and ethnographic studies among indigenous people are common practice in health and geographical research. Prior health research misconduct has been documented, particularly when obtaining genetic ma...
Forgoing life-sustaining treatment - a comparative analysis of regulations in Japan, Korea, Taiwan, and England [0.03%]
放弃维持生命治疗 - 日本、韩国、台湾和英格兰的规范比较分析
Miho Tanaka,Satoshi Kodama,Ilhak Lee et al.
Miho Tanaka et al.
Background: Regulations on forgoing life-sustaining treatment (LST) have developed in Asian countries including Japan, Korea and Taiwan. However, other countries are relatively unaware of these due to the language barrier...
Challenges to effective and autonomous genetic testing and counseling for ethno-cultural minorities: a qualitative study [0.03%]
针对民族文化少数群体有效自主基因检测和咨询的挑战:一项质性研究
Nehama Cohen-Kfir,Miriam Ethel Bentwich,Andrew Kent et al.
Nehama Cohen-Kfir et al.
Background: The Arab population in Israel is a minority ethnic group with its own distinct cultural subgroups. Minority populations are known to underutilize genetic tests and counseling services, thereby undermining the ...