Ethics review of big data research: What should stay and what should be reformed? [0.03%]
大数据研究的伦理审查：坚守与改革何处寻？
Agata Ferretti,Marcello Ienca,Mark Sheehan et al.
Agata Ferretti et al.
Background: Ethics review is the process of assessing the ethics of research involving humans. The Ethics Review Committee (ERC) is the key oversight mechanism designated to ensure ethics review. Whether or not this gover...
A scoping review of the literature featuring research ethics and research integrity cases [0.03%]
一项关于研究伦理和研究诚信案例文献的范围评估审核
Anna Catharina Vieira Armond,Bert Gordijn,Jonathan Lewis et al.
Anna Catharina Vieira Armond et al.
Background: The areas of Research Ethics (RE) and Research Integrity (RI) are rapidly evolving. Cases of research misconduct, other transgressions related to RE and RI, and forms of ethically questionable behaviors have b...
Ethical and procedural issues for applying researcher-driven multi-national paediatric clinical trials in and outside the European Union: the challenging experience of the DEEP project [0.03%]
欧盟内外研究人员主导的多国儿科临床试验的应用伦理及程序问题——来自DEEP项目的挑战经验教训
Viviana Giannuzzi,Mariagrazia Felisi,Donato Bonifazi et al.
Viviana Giannuzzi et al.
Background: We describe our experience from a multi-national application of a European Union-funded research-driven paediatric trial (DEEP-2, EudraCT 2012-000353-31; NCT01825512). This paper aims to evaluate the impact of...
A Q methodology study on divergent perspectives on CRISPR-Cas9 in the Netherlands [0.03%]
荷兰CRISPR-Cas9技术不同观点的Q方法研究
Mirjam Schuijff,Menno D T De Jong,Anne M Dijkstra
Mirjam Schuijff
Background: CRISPR-Cas9, a technology enabling modification of the human genome, is developing rapidly. There have been calls for public debate to discuss its ethics, societal implications, and governance. So far, however...
Recognising values and engaging communities across cultures: towards developing a cultural protocol for researchers [0.03%]
跨文化的价值观认同与社区参与——面向研究者的文化行为规范之构建初探
Rakhshi Memon,Muqaddas Asif,Ameer B Khoso et al.
Rakhshi Memon et al.
Efforts to build research capacity and capability in low and middle income countries (LMIC) has progressed over the last three decades, yet it confronts many challenges including issues with communicating or even negotiating across differen...
Petr Talantov,Ravil Niyazov,Galina Viryasova et al.
Petr Talantov et al.
Background: In modern Russia, any clinical investigation of a pharmaceutical for use in humans is subject to prior evaluation and approval by the Ministry of Health and its Central Ethics Committee. Despite this, some res...
Trust and professionalism in science: medical codes as a model for scientific negligence? [0.03%]
医学准则作为科学研究失职的模型对科学的信任和专业性的思考
Hugh Desmond,Kris Dierickx
Hugh Desmond
Background: Professional communities such as the medical community are acutely concerned with negligence: the category of misconduct where a professional does not live up to the standards expected of a professional of sim...
Identifying disincentives to ethics consultation requests among physicians, advance practice providers, and nurses: a quality improvement all staff survey at a tertiary academic medical center [0.03%]
三级学术医学中心质量改进全员调查中识别医师、高级执业提供者和护士对伦理咨询请求的负面激励因素
Lynette Cederquist,Jamie Nicole LaBuzetta,Edward Cachay et al.
Lynette Cederquist et al.
Background: Ethics consult services are well established, but often remain underutilized. Our aim was to identify the barriers and perceptions of the Ethics consult service for physicians, advance practice providers (APPs...
Inter-physician variability in strategies linked to treatment limitations after severe traumatic brain injury; proactivity or wait-and-see [0.03%]
严重颅脑损伤后治疗限制的相关策略的医生间差异：积极行动还是等待观察？
Annette Robertsen,Eirik Helseth,Reidun Førde
Annette Robertsen
Background: Prognostic uncertainty is a challenge for physicians in the neuro intensive care field. Questions about whether continued life-sustaining treatment is in a patient's best interests arise in different phases af...
Under consent: participation of people with HIV in an Ebola vaccine trial in Canada [0.03%]
知情同意的伦理审查：加拿大HIV感染者参与埃博拉疫苗试验项目中的受试者权益保护问题
Pierre-Marie David,Benjamin Mathiot,Oumy Thiongane et al.
Pierre-Marie David et al.
Background: Little is known about volunteers from Northern research settings who participate in vaccine trials of highly infectious diseases with no approved treatments. This article explores the motivations of HIV immuno...