Interleukin-1 beta: a potential link between stress and the development of visceral obesity [0.03%]
细胞因子白介素-1β可能是精神压力与内脏型肥胖发生机制之间联系的环节之一
Kristin J Speaker,Monika Fleshner
Kristin J Speaker
Background: A disproportionate amount of body fat within the abdominal cavity, otherwise known as visceral obesity, best predicts the negative health outcomes associated with high levels body fat. Growing evidence suggest...
Cell proliferation along vascular islands during microvascular network growth [0.03%]
微血管网络生长过程中血管岛周围的细胞增殖现象
Molly R Kelly-Goss,Erica R Winterer,Peter C Stapor et al.
Molly R Kelly-Goss et al.
Background: Observations in our laboratory provide evidence of vascular islands, defined as disconnected endothelial cell segments, in the adult microcirculation. The objective of this study was to determine if vascular i...
Mechanisms of pressure-diuresis and pressure-natriuresis in Dahl salt-resistant and Dahl salt-sensitive rats [0.03%]
Dahl盐抵抗型和Dahl盐敏感型大鼠压力利尿和压力钠尿的机制研究
Daniel A Beard,Muriel Mescam
Daniel A Beard
Background: Data on blood flow regulation, renal filtration, and urine output in salt-sensitive Dahl S rats fed on high-salt (hypertensive) and low-salt (prehypertensive) diets and salt-resistant Dahl R rats fed on high-s...
Contractile properties and movement behaviour in neonatal rats with axotomy, treated with the NMDA antagonist DAP5 [0.03%]
用DAP5处理轴突切断的新生大鼠的收缩性能及其运动行为学特点研究
Konstantinos Petsanis,Athanasios Chatzisotiriou,Dorothea Kapoukranidou et al.
Konstantinos Petsanis et al.
Background: It is well known that axotomy in the neonatal period causes massive loss of motoneurons, which is reflected in the reduction of the number of motor units and the alteration in muscle properties. This type of n...
Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels [0.03%]
肥胖相关的胰岛素抵抗与血管内皮生长因子及金属基质蛋白酶水平相关性研究
Francisco José Tinahones,Leticia Coín-Aragüez,Maria Dolores Mayas et al.
Francisco José Tinahones et al.
Background: The expansion of adipose tissue is linked to the development of its vasculature, which appears to have the potential to regulate the onset of obesity. However, at present, there are no studies highlighting the...
Small molecule screening platform for assessment of cardiovascular toxicity on adult zebrafish heart [0.03%]
基于成年斑马鱼心脏的小分子心血管毒性筛选平台
Satish Srinivas Kitambi,Erik S Nilsson,Petra Sekyrova et al.
Satish Srinivas Kitambi et al.
Background: Cardiovascular toxicity is a major limiting factor in drug development and requires multiple cost-effective models to perform toxicological evaluation. Zebrafish is an excellent model for many developmental, t...
Matrix metalloproteinases 2 and 9 increase permeability of sheep pleura in vitro [0.03%]
基质金属蛋白酶2和9通过体外实验增加羊胸膜通透性
Eleni Apostolidou,Efrosyni Paraskeva,Konstantinos Gourgoulianis et al.
Eleni Apostolidou et al.
Background: Matrix metalloproteinases (MMPs) 2 and 9 are two gelatinase members which have been found elevated in exudative pleural effusions. In endothelial cells these MMPs increase paracellular permeability via the dis...
Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion [0.03%]
肝c-myc条件性删除小鼠模型中，出生后肝生长和再生不受c-myc影响
Jennifer A Sanders,Christoph Schorl,Ajay Patel et al.
Jennifer A Sanders et al.
Background: The transcription factor c-myc regulates genes involved in hepatocyte growth, proliferation, metabolism, and differentiation. It has also been assigned roles in liver development and regeneration. In previous ...
HOXA4 protein levels and localization in the aorta and in human abdominal aortic aneurysms [0.03%]
人腹主动脉瘤和正常腹主动脉组织中HOXA4蛋白水平及定位差异分析
Christian Klausen,Nelly Auersperg
Christian Klausen
This report presents evidence for the specificities of select commercially available HOXA4 antibodies in regards to concerns about the specificity of the HOXA4 antibody used by Lillvis et al. (Regional expression of HOXA4 along the aorta an...
Effect of prolonged standardized bed rest on cystatin C and other markers of cardiovascular risk [0.03%]
长期标准化卧床休息对半胱氨酸C和其他心血管风险标志物的影响
Karin Arinell,Kjeld Christensen,Stéphane Blanc et al.
Karin Arinell et al.
Background: Sedentary lifestyle is associated with coronary artery disease but even shorter periods of physical inactivity may increase cardiovascular risk. Cystatin C is independently associated with cardiovascular disea...
Randomized Controlled Trial
BMC physiology. 2011 Dec 9:11:17. DOI:10.1186/1472-6793-11-17 2011