The antioxidant response of the liver of male Swiss mice raised on a AIN 93 or commercial diet [0.03%]
分别喂食AIN-93和普通饲料的雄性瑞士小鼠肝脏抗氧化应答的差异
Aline C Caetano,Lucimara F da Veiga,Flávia R Capaldi et al.
Aline C Caetano et al.
Background: Reactive oxygen species (ROS) are formed under natural physiological conditions and are thought to play an important role in many human diseases. A wide range of antioxidants are involved in cellular defense m...
Genomic homeostasis is dysregulated in favour of apoptosis in the colonic epithelium of the azoxymethane treated rat [0.03%]
偶氮甲烷处理的大鼠结肠黏膜上皮细胞基因组稳定性和凋亡的改变
Caroline A Kerr,Barney M Hines,Janet M Shaw et al.
Caroline A Kerr et al.
Background: The acute response to genotoxic carcinogens in rats is an important model for researching cancer initiation events. In this report we define the normal rat colonic epithelium by describing transcriptional even...
Disease resistance is related to inherent swimming performance in Atlantic salmon [0.03%]
鱼类游泳能力影响疾病抗性：以大西洋鲑鱼为例
Vicente Castro,Barbara Grisdale-Helland,Sven M Jørgensen et al.
Vicente Castro et al.
Background: Like humans, fish can be classified according to their athletic performance. Sustained exercise training of fish can improve growth and physical capacity, and recent results have documented improved disease re...
VEGF induces sensory and motor peripheral plasticity, alters bladder function, and promotes visceral sensitivity [0.03%]
VEGF诱导外周感觉和运动的可塑性，改变膀胱功能并促进内脏敏感度
Anna P Malykhina,Qi Lei,Chris S Erickson et al.
Anna P Malykhina et al.
Background: This work tests the hypothesis that bladder instillation with vascular endothelial growth factor (VEGF) modulates sensory and motor nerve plasticity, and, consequently, bladder function and visceral sensitivit...
Localization of lipoprotein lipase and GPIHBP1 in mouse pancreas: effects of diet and leptin deficiency [0.03%]
脂蛋白脂肪酶和GPIHBP1在小鼠胰腺中的定位：饮食和瘦素缺乏的影响
Rakel Nyrén,Chuchun L Chang,Per Lindström et al.
Rakel Nyrén et al.
Background: Lipoprotein lipase (LPL) hydrolyzes triglycerides in plasma lipoproteins and enables uptake of lipolysis products for energy production or storage in tissues. Our aim was to study the localization of LPL and i...
Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue [0.03%]
营养调节Angptl4、Gpihbp1和Lmf1与啮齿动物脂肪组织的脂蛋白脂肪酶活性的关系
Olessia Kroupa,Evelina Vorrsjö,Rinke Stienstra et al.
Olessia Kroupa et al.
Background: Lipoprotein lipase (LPL) hydrolyzes triglycerides in lipoproteins and makes fatty acids available for tissue metabolism. The activity of the enzyme is modulated in a tissue specific manner by interaction with ...
The ΔF508-CFTR mutation inhibits wild-type CFTR processing and function when co-expressed in human airway epithelia and in mouse nasal mucosa [0.03%]
ΔF508-CFTR突变抑制人在呼吸道上皮和小鼠鼻粘膜中野生CFTR的加工及功能
Torry A Tucker,James A Fortenberry,Akos Zsembery et al.
Torry A Tucker et al.
Background: Rescue or correction of CFTR function in native epithelia is the ultimate goal of CF therapeutics development. Wild-type (WT) CFTR introduction and replacement is also of particular interest. Such therapies ma...
High molecular mass proteomics analyses of left ventricle from rats subjected to differential swimming training [0.03%]
不同游泳训练大鼠左心室高分子量蛋白质组学分析
Luiz A O Rocha,Bernardo A Petriz,David H Borges et al.
Luiz A O Rocha et al.
Background: Regular exercises are commonly described as an important factor in health improvement, being directly related to contractile force development in cardiac cells.In order to evaluate the links between swimming e...
Contribution of transient and sustained calcium influx, and sensitization to depolarization-induced contractions of the intact mouse aorta [0.03%]
瞬时和持续性钙离子流入以及去极化诱导的收缩对完整鼠主动脉敏化作用的贡献
Paul Fransen,Cor E Van Hove,Johanna van Langen et al.
Paul Fransen et al.
Background: Electrophysiological studies of L-type Ca2+ channels in isolated vascular smooth muscle cells revealed that depolarization of these cells evoked a transient and a time-independent Ca2+ current. The sustained, ...
Identification of uterine ion transporters for mineralisation precursors of the avian eggshell [0.03%]
家禽蛋壳矿化前体的子宫离子转运蛋白鉴定
Vincent Jonchère,Aurélien Brionne,Joël Gautron et al.
Vincent Jonchère et al.
Background: In Gallus gallus, eggshell formation takes place daily in the hen uterus and requires large amounts of the ionic precursors for calcium carbonate (CaCO3). Both elements (Ca2+, HCO3-) are supplied by the blood ...