Age-dependent changes in 24-hour rhythms of catecholamine content and turnover in hypothalamus, corpus striatum and pituitary gland of rats injected with Freund's adjuvant [0.03%]
完全弗氏佐剂注射大鼠不同发育阶段纹状体、下丘脑及垂体儿茶酚胺含量与更新的昼夜节律变化规律研究
P Cano,D P Cardinali,F Chacon et al.
P Cano et al.
Background: Little information is available on the circadian sequela of an immune challenge in the brain of aged rats. To assess them, we studied 24-hour rhythms in hypothalamic and striatal norepinephrine (NE) content, h...
The dynamics of venous return and response to hypervolemia in the toad, Bufo marinus (L.) [0.03%]
Bufo marinus (L.)的静脉回流动力学及其对过量输液的反应
E E Killorn,D P Toews
E E Killorn
Background: Venous return from the posterior region of amphibians travels by either two renal portal veins to the kidney or a central abdominal vein that drains into the hepatic portal system. The relative proportions of ...
High calcium and dobutamine positive inotropy in the perfused mouse heart: myofilament calcium responsiveness, energetic economy, and effects of protein kinase C inhibition [0.03%]
高钙和多巴胺正性肌力对灌注小鼠心脏的作用：肌小节的钙敏感性、能量效益及蛋白激酶C抑制的影响
G A MacGowan,C Du,A P Koretsky
G A MacGowan
Background: In perfused hearts, high calcium-induced inotropy results in less developed pressure relative to myocardial oxygen consumption compared to the beta-adrenergic agonist dobutamine. Calcium handling is an importa...
Comparative Study
BMC physiology. 2001:1:12. DOI:10.1186/1472-6793-1-12 2001
1,25-Dihydroxyvitamin D3 increases the expression of the CaT1 epithelial calcium channel in the Caco-2 human intestinal cell line [0.03%]
1,25-二羟基维生素D3通过上调CaT1上皮钙通道的表达增加Caco-2人肠细胞系中钙的吸收
R J Wood,L Tchack,S Taparia
R J Wood
Background: The active hormonal form of vitamin D (1,25-dihydroxyvitamin D) is the primary regulator of intestinal calcium absorption efficiency. In vitamin D deficiency, intestinal calcium absorption is low leading to an...
C M Rembold,E Zhang
C M Rembold
Background: Cyclic nucleotides can relax vascular smooth muscle by mechanisms distal to myosin regulatory light chain (MRLC) phosphorylation. This mechanism, termed relaxation without MRLC dephosphorylation, may be regula...
Dopaminergic neurons in the brain and dopaminergic innervation of the albumen gland in mated and virgin helisoma duryi (mollusca: pulmonata) [0.03%]
脑中的多巴胺能神经元及交配和未交配的 Helisoma duryi(软件动物：肺枝腔类)中的卵白腺多巴胺能投射
L Kiehn,S Saleuddin,A Lange
L Kiehn
Background: Dopamine was shown to stimulate the perivitelline fluid secretion by the albumen gland. Even though the albumen gland has been shown to contain catecholaminergic fibers and its innervation has been studied, th...
Comparative Study
BMC physiology. 2001:1:9. DOI:10.1186/1472-6793-1-9 2001
Modulation of L-type Ca2+ current but not activation of Ca2+ release by the gamma1 subunit of the dihydropyridine receptor of skeletal muscle [0.03%]
骨骼肌二氢吡啶受体γ1亚单位调节L型Ca2+电流但不能激活钙释放
C A Ahern,P A Powers,G H Biddlecome et al.
C A Ahern et al.
Background: The multisubunit (alpha1S,alpha2-delta, beta1a and gamma1) skeletal muscle dihydropyridine receptor (DHPR) transduces membrane depolarization into release of Ca2+ from the sarcoplasmic reticulum (SR) and also ...
V Chu,J M Otero,O Lopez et al.
V Chu et al.
Background: The rapid increase in the development of mouse models is resulting in a growing demand for non-invasive physiological monitoring of large quantities of mice. Accordingly, we developed a new system for recordin...
Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown [0.03%]
一种色氨酸代谢物-xanthurenic酸诱导的病理凋亡：活化细胞caspase但不导致胞浆骨架解体
H Z Malina,C Richter,M Mehl et al.
H Z Malina et al.
Background: A family of aspartate-specific cysteinyl proteases, named caspases, mediates programmed cell death, apoptosis. In this function, caspases are important for physiological processes such as development and maint...
Endothelial [Ca2+]i is an integrating signal for the vascular tone in rat aortae [0.03%]
内皮细胞钙离子浓度是调控大鼠主动脉血管张力的信号分子
T Y Huang,H Chen,C Y Liu et al.
T Y Huang et al.
Background: Although various endothelium-dependent relaxing factors (endothelial autacoids) are released upon the elevation of endothelial cytosolic free Ca2+ concentration (EC [Ca2+]i), the quantitative relationship betw...