Effect of the degree of ischaemic injury and reoxygenation time on the type of myocardial cell death in man: role of caspases [0.03%]
缺血损伤程度和再氧合时间对人体心肌细胞死亡方式的影响：活化级联中各胱天蛋白酶的作用
Hunaid A Vohra,Manuel Galiñanes
Hunaid A Vohra
Background: The importance of apoptosis in the injury sustained by the human myocardium during ischaemia and reoxygenation and the underlying mechanisms remain unclear. To quantify apoptosis and necrosis induced by simula...
Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B [0.03%]
肝细胞分化细胞系WIF-B中水通道蛋白的表达及其亚细胞定位
Sergio A Gradilone,Pamela S Tietz,Patrick L Splinter et al.
Sergio A Gradilone et al.
Background: Recent data suggest that canalicular bile secretion involves selective expression and coordinated regulation of aquaporins (AQPs), a family of water channels proteins. In order to further characterize the role...
Fatigue resistance of rat extraocular muscles does not depend on creatine kinase activity [0.03%]
大鼠眼外肌的抗疲劳性不受 Creatine Kinase 活性的影响
Colleen A McMullen,Katrin Hayess,Francisco H Andrade
Colleen A McMullen
Background: Creatine kinase (CK) links phosphocreatine, an energy storage system, to cellular ATPases. CK activity serves as a temporal and spatial buffer for ATP content, particularly in fast-twitch skeletal muscles. The...
Metabolic adaptations to repeated periods of contraction with reduced blood flow in canine skeletal muscle [0.03%]
犬骨骼肌反复收缩和血液减少的代谢适应性
Alan MacInnes,James A Timmons
Alan MacInnes
Background: Patients suffering from Intermittent Claudication (IC) experience repeated periods of muscle contraction with low blood flow, throughout the day and this may contribute to the hypothesised skeletal muscle abno...
Thomas H Adair,Reid Cotten,Jian-Wei Gu et al.
Thomas H Adair et al.
Background: Many in vitro studies have shown that adenosine (Ado) can induce vascular endothelial growth factor (VEGF) mRNA and protein expression and stimulate endothelial proliferation. In the present study, we seek to ...
PI3K and PKC contribute to membrane depolarization mediated by alpha2-adrenoceptors in the canine isolated mesenteric vein [0.03%]
犬孤立肠系膜静脉中α2-肾上腺素受体介导的细胞膜去极化与PI3K和PKC有关
Ilia A Yamboliev,Violeta N Mutafova-Yambolieva
Ilia A Yamboliev
Background: Norepinephrine (NE), a classic neurotransmitter in the sympathetic nervous system, induces vasoconstriction of canine isolated mesenteric vein that is accompanied by a sustained membrane depolarization. The me...
Exploring hepatic hormone actions using a compilation of gene expression profiles [0.03%]
利用基因表达谱分析探索肝脏激素的作用机制
Nina Ståhlberg,Roxana Merino,Luis Henríquez Hernández et al.
Nina Ståhlberg et al.
Background: Microarray analysis is attractive within the field of endocrine research because regulation of gene expression is a key mechanism whereby hormones exert their actions. Knowledge discovery and testing of hypoth...
Meta-Analysis
BMC physiology. 2005 Jun 13;5(1):8. DOI:10.1186/1472-6793-5-8 2005
Phrenic nerve afferents elicited cord dorsum potential in the cat cervical spinal cord [0.03%]
猫颈脊髓膈神经传入引起的背根电位
Yang-Ling Chou,Paul W Davenport
Yang-Ling Chou
Background: The diaphragm has sensory innervation from mechanoreceptors with myelinated axons entering the spinal cord via the phrenic nerve that project to the thalamus and somatosensory cortex. It was hypothesized that ...
PKC translocation and ERK1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysema [0.03%]
慢性肺气肿继发的代偿性右心室肥大的PKC再定位和ERK1/2活化
Erick Avelar,Thunder Jalili,Li Dong et al.
Erick Avelar et al.
Background: Right ventricular hypertrophy (RVH) is an important complication of chronic lung disease. However, the signal transduction pathways involved as well as the physiological changes to the right ventricle have not...
Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects [0.03%]
慢性疲劳综合征外周血响应基因的测量
Toni Whistler,James F Jones,Elizabeth R Unger et al.
Toni Whistler et al.
Background: Chronic fatigue syndrome (CFS) is defined by debilitating fatigue that is exacerbated by physical or mental exertion. To search for markers of CFS-associated post-exertional fatigue, we measured peripheral blo...