Decrease in oxidative phosphorylation yield in presence of butyrate in perfused liver isolated from fed rats [0.03%]
喂养大鼠肝内灌流器中丁酸存在的氧化磷酸化产能的减少
Jean-Louis Gallis,Pierre Tissier,Henri Gin et al.
Jean-Louis Gallis et al.
Background: Butyrate is the main nutrient for the colonocytes but the effect of the fraction reaching the liver is not totally known. A decrease in tissue ATP content and increase in respiration was previously demonstrate...
Divergent calcium signaling in RBCs from Tropidurus torquatus (Squamata--Tropiduridae) strengthen classification in lizard evolution [0.03%]
来自Tropidurus torquatus(蜥蜴科--Tropiduridae)的红细胞中分歧的钙信号增强蜥蜴进化的分类
Flávio H Beraldo,Célia R S Garcia
Flávio H Beraldo
Background: We have previously reported that a Teiid lizard red blood cells (RBCs) such as Ameiva ameiva and Tupinambis merianae controls intracellular calcium levels by displaying multiple mechanisms. In these cells, cal...
Comparative Study
BMC physiology. 2007 Aug 23:7:7. DOI:10.1186/1472-6793-7-7 2007
Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca2+-dependent PKC isoforms [0.03%]
泌乳素通过差异调节Ca2+依赖的PKC异构体刺激正常女性胆管细胞增殖
Silvia Taffetani,Shannon Glaser,Heather Francis et al.
Silvia Taffetani et al.
Background: Prolactin promotes proliferation of several cells. Prolactin receptor exists as two isoforms: long and short, which activate different transduction pathways including the Ca2+-dependent PKC-signaling. No infor...
Comparative Study
BMC physiology. 2007 Jul 19:7:6. DOI:10.1186/1472-6793-7-6 2007
Toll-like receptor 4 deficiency: smaller infarcts, but no gain in function [0.03%]
toll-like受体4缺乏:较小的梗死面积,但无功能获益
Se-Chan Kim,Alexander Ghanem,Heidi Stapel et al.
Se-Chan Kim et al.
Background: It has been reported that Toll-like receptor 4 (TLR4) deficiency reduces infarct size after myocardial ischemia/reperfusion (MI/R). However, measurement of MI/R injury was limited and did not include cardiac f...
Mandatory role of proteinase-activated receptor 1 in experimental bladder inflammation [0.03%]
蛋白酶活化受体1在实验性膀胱炎中发挥重要作用
Ricardo Saban,Michael R DAndrea,Patricia Andrade-Gordon et al.
Ricardo Saban et al.
Background: In general, inflammation plays a role in most bladder pathologies and represents a defense reaction to injury that often times is two edged. In particular, bladder neurogenic inflammation involves the particip...
Regulatory network of inflammation downstream of proteinase-activated receptors [0.03%]
蛋白酶激活受体下游炎症的调控网络
Ricardo Saban,Michael R DAndrea,Patricia Andrade-Gordon et al.
Ricardo Saban et al.
Background: Protease-activated receptors (PAR) are present in the urinary bladder, and their expression is altered in response to inflammation. PARs are a unique class of G protein-coupled that carry their own ligands, wh...
Systemic administration of IGF-I enhances healing in collagenous extracellular matrices: evaluation of loaded and unloaded ligaments [0.03%]
胰岛素样生长因子I对胶原基质的修复作用及对加载与未加载韧带的评价研究
Paolo P Provenzano,Adriana L Alejandro-Osorio,Kelley W Grorud et al.
Paolo P Provenzano et al.
Background: Insulin-like growth factor-I (IGF-I) plays a crucial role in wound healing and tissue repair. We tested the hypotheses that systemic administration of IGF-I, or growth hormone (GH), or both (GH+IGF-I) would im...
Comparative Study
BMC physiology. 2007 Mar 26:7:2. DOI:10.1186/1472-6793-7-2 2007
A novel method for the evaluation of proximal tubule epithelial cellular necrosis in the intact rat kidney using ethidium homodimer [0.03%]
一种在完整的大鼠肾脏中评估近端小管上皮细胞坏死的新方法——应用双链乙锭法
Joshua R Edwards,Evangelos A Diamantakos,Jacob D Peuler et al.
Joshua R Edwards et al.
Background: Ethidium homodimer is a cell-membrane impermeant nuclear fluorochrome that has been widely used to identify necrotic cells in culture. Here, we describe a novel technique for evaluating necrosis of epithelial ...
Protein expression of G-protein inwardly rectifying potassium channels (GIRK) in breast cancer cells [0.03%]
乳腺癌细胞中G蛋白活化的内向整流钾通道(GIRK)的表达研究
Madhu S Dhar,Howard K Plummer rd
Madhu S Dhar
Background: Previous data from our laboratory has indicated that a functional link exists between the G-protein-coupled inwardly rectifying potassium (GIRK) channel and the beta-adrenergic receptor pathway in breast cance...
Inspiratory resistances facilitate the diaphragm response to transcranial stimulation in humans [0.03%]
inspiration时的阻力有助于人类颅神经对横膈膜的刺激响应
Chrystèle Locher,Mathieu Raux,Marie-Noelle Fiamma et al.
Chrystèle Locher et al.
Background: Breathing in humans is dually controlled for metabolic (brainstem commands) and behavioral purposes (suprapontine commands) with reciprocal modulation through spinal integration. Whereas the ventilatory respon...