Intermediate FMR1 cytosine‒guanine‒guanine repeats do not impair assisted reproductive technology outcomes in a large real-world cohort [0.03%]
中等长度FMR1 CGG重复不影响大型真实世界人群的辅助生殖技术结局
Adi Dayan-Schwartz,Nitzan Dana Sela,Ido Izhaki et al.
Adi Dayan-Schwartz et al.
Research question: Does the presence of moderately elevated FMR1 cytosine‒guanine‒guanine (CGG) repeat numbers (40-70 repeats), identified through routine pre-pregnancy screening, adversely affect assisted reproductive ...
Integrating PGT-A into PGT-M protocols in young ART-naïve patients undergoing single embryo transfer [0.03%]
年轻一代试管婴儿新手患者单胚胎移植中将PGT-A整合入PGT-M方案中
Frauke Vanden Meerschaut,Emma Deweirdt,Margot Kint et al.
Frauke Vanden Meerschaut et al.
Research question: What are the effects of integrating preimplantation genetic testing for aneuploidy into preimplantation genetic testing for monogenic/single gene disorders (PGT-M), termed 'comprehensive PGT' (coPGT-M)?...
Evolutionary and epigenetic drivers of the global trajectory of sperm count decline: an integrative framework for male reproductive health [0.03%]
精子计数下降的全球轨迹的进化和表观遗传驱动因素：男性生殖健康的一体化框架
Enver Kerem Dirican
Enver Kerem Dirican
Global meta-analyses have documented a decline in sperm concentration of approximately 50% since the 1970s, with rates accelerating from 1.16% to 2.64% annually. A parallel decline in serum testosterone (approximately 1.2%/year) has been do...
Effect of a pro-fertility diet combined with omega-3 supplementation on embryo quality in infertile women undergoing IVF: a randomized controlled trial [0.03%]
一种促生育饮食联合补充欧米伽-3对接受试管婴儿治疗的不孕女性胚胎质量的影响：一项随机对照试验
Mahnaz Ghadimi Yari,Hatav Ghasemi-Tehrani,Awat Feizi et al.
Mahnaz Ghadimi Yari et al.
Research question: Does adherence to a pro-fertility diet (PFD) combined with omega-3 supplementation improve the fertilization rate and embryo quality in infertile women undergoing IVF? ...
Advancing maternal age worsens pregnancy outcomes following single frozen embryo transfer with preimplantation genetic testing [0.03%]
高龄对冻胚移植前筛查妊娠结局的影响
Chunyan Luo,Xiaohan Zhang,Jing Li et al.
Chunyan Luo et al.
Research question: What is the critical age for the onset of deterioration in pregnancy outcomes associated with advancing maternal age in frozen embryo transfer (FET) cycles following preimplantation genetic testing (PGT...
Endometrial metabolomic profiling reveals disruption of fatty-acid metabolism in unexplained recurrent pregnancy loss [0.03%]
子宫内膜代谢组学分析揭示不明原因复发性妊娠丢失患者脂肪酸代谢紊乱
Magalie Boguenet,Mathieu Michel,Cinzia Bocca et al.
Magalie Boguenet et al.
Research question: Are specific plasma or endometrial metabolomic profiles associated with recurrent implantation failure (RIF), unexplained recurrent pregnancy loss (U-RPL), or both? ...
Helping patients achieve their expected live birth rate: an ART paradigm shift [0.03%]
助力患者实现预期活产率：辅助生殖技术的范式转换
Luca Gianaroli,Edgar Mocanu,Human Fatemi et al.
Luca Gianaroli et al.
Since its early days, assisted reproductive technology (ART) has undergone tremendous developments and is now largely used to treat a wide range of causes of infertility and to prevent the transmission of genetic disorders. Nevertheless, su...
Pregnancy outcomes after warm, biopsy and refreeze cycles of previously untested vitrified blastocysts [0.03%]
既往未经检测的玻璃化囊胚直接复苏、活检及冻融后移植妊娠结局分析
Valerie Chen,Si Won Lee,David L Walker et al.
Valerie Chen et al.
Research question: Do pregnancy outcomes differ between euploid embryos after warm, biopsy and refreeze (WBR) of previously vitrified blastocysts and euploid blastocysts biopsied before initial vitrification? ...
David Sable
David Sable
In the 66 years since the introduction of clomiphene citrate, the 64 years since the first pregnancy using menotrophin stimulation and the 48 years since the birth of the first baby conceived through IVF, the procedures that have been devel...
Incidence of abnormal cleavage patterns in conventional IVF versus ICSI: a retrospective analysis of 125,570 normally fertilised embryos [0.03%]
常规IVF与ICSI的分裂模式异常发生率回顾性分析：基于125570个正常受精胚胎的数据
Weiwei Liu,Jun Shuai,Xiaoni Guo et al.
Weiwei Liu et al.
Research question: Do the different fertilisation methods of conventional in vitro fertilisation (cIVF) or intracytoplasmic sperm injection (ICSI) affect abnormal cleavage (ABNCL) of early embryos? ...