Leonard Barasa,Paul R Thompson
Leonard Barasa
Protein citrullination is a post-translational modification (PTM) that is catalysed by the protein arginine deiminase (PAD) family of enzymes. This PTM involves the transformation of an arginine residue into citrulline. Protein citrullinati...
PADI6: What we know about the elusive fifth member of the peptidyl arginine deiminase family [0.03%]
PADI6：关于肽精氨酸脱亚胺酶家族第五成员我们知道些什么
Jack P C Williams,Louise J Walport
Jack P C Williams
Peptidyl arginine deiminase 6 (PADI6) is a maternal factor that is vital for early embryonic development. Deletion and mutations of its encoding gene in female mice or women lead to early embryonic developmental arrest, female infertility, ...
Co-expression of PADI isoforms during progenitor differentiation enables functional diversity [0.03%]
PADI异构体在祖细胞分化过程中的共表达可实现功能多样性
Kim Vikhe Patil,Mandy Meijer,Kylie Hin-Man Mak et al.
Kim Vikhe Patil et al.
Protein isoforms, generated through alternative splicing or promoter usage, contribute to tissue function. Here, we characterize the expression of predicted Padi3α and Padi3β isoforms in hair follicles and describe expression of Padi2β, ...
Anne Pisor,J Stephen Lansing,Kate Magargal
Anne Pisor
There is global consensus that we must immediately prioritize climate change adaptation-change in response to or anticipation of risks from climate change. Some researchers and policymakers urge 'transformative change', a complete break fro...
Climate micro-mobilities as adaptation practice in the Pacific: the case of Samoa [0.03%]
太平洋地区的气候微流动性适应实践：以萨摩亚为例
Anita Latai-Niusulu,Masami Tsujita,Andreas Neef
Anita Latai-Niusulu
Recent debates on climate mobilities have largely ignored the dynamics of mobility patterns including short-distance and short-duration circular movements to enhance adaptative capacity and resilience of households and individuals, enabling...
Understanding constraints to adaptation using a community-centred toolkit [0.03%]
基于社区的适应工具包理解适应限制因素
Danielle C Buffa,Katharine E T Thompson,Dana Reijerkerk et al.
Danielle C Buffa et al.
Worldwide, marginalized and low-income communities will disproportionately suffer climate change impacts while also retaining the least political power to mitigate their consequences. To adapt to environmental shocks, communities must balan...
H Clark Barrett,Josh Armstrong
H Clark Barrett
A good deal of contemporary work in cultural evolutionary theory focuses on the adaptive significance of culture. In this paper, we make the case that scientifically accurate and politically feasible responses to the climate crisis require ...
Efficiency traps beyond the climate crisis: exploration-exploitation trade-offs and rebound effects [0.03%]
超越气候危机的效率陷阱：探索与开发之间的权衡以及反弹效应
Jose Segovia-Martin,Felix Creutzig,James Winters
Jose Segovia-Martin
Higher levels of economic activity are often accompanied by higher energy use and consumption of natural resources. As fossil fuels still account for 80% of the global energy mix, energy consumption remains closely linked to greenhouse gas ...
Navigating polycrisis: long-run socio-cultural factors shape response to changing climate [0.03%]
应对气候变化的多危机：长期的社会文化因素的影响
Daniel Hoyer,James S Bennett,Jenny Reddish et al.
Daniel Hoyer et al.
Climate variability and natural hazards like floods and earthquakes can act as environmental shocks or socioecological stressors leading to instability and suffering throughout human history. Yet, societies experience a wide range of outcom...
Minority-group incubators and majority-group reservoirs support the diffusion of climate change adaptations [0.03%]
少数群体的孵化器和多数群体的蓄水池支持气候适应措施的扩散
Matthew A Turner,Alyson L Singleton,Mallory J Harris et al.
Matthew A Turner et al.
Successful climate change adaptation depends on the spread and maintenance of adaptive behaviours. Current theory suggests that the heterogeneity of metapopulation structure can help adaptations diffuse throughout a population. In this pape...