Jean-Luc Imler,Hua Cai,Carine Meignin et al.
Jean-Luc Imler et al.
Over the past 25 years, the field of evolutionary developmental biology (evo-devo) has used genomics and genetics to gain insight on the developmental mechanisms underlying the evolution of morphological diversity of animals. Evo-devo explo...
Photosynthesis and other factors affecting the establishment and maintenance of cnidarian-dinoflagellate symbiosis [0.03%]
光合作用及其他刺胞动物-藻类共生建立和维持的影响因素
Cawa Tran,Gabriel R Rosenfield,Phillip A Cleves et al.
Cawa Tran et al.
Coral growth depends on the partnership between the animal hosts and their intracellular, photosynthetic dinoflagellate symbionts. In this study, we used the sea anemone Aiptasia, a laboratory model for coral biology, to investigate the poo...
Understanding the factors regulating host-microbiome interactions using Caenorhabditis elegans [0.03%]
利用秀丽隐杆线虫理解宿主微生物组相互作用的调节因素
Anupama Singh,Robert J Luallen
Anupama Singh
The Human Microbiome Project was a research programme that successfully identified associations between microbial species and healthy or diseased individuals. However, a major challenge identified was the absence of model systems for studyi...
When the microbiome shapes the host: immune evolution implications for infectious disease [0.03%]
当微生物群影响宿主时：传染病的免疫进化意义
Mark A Hanson
Mark A Hanson
The microbiome includes both 'mutualist' and 'pathogen' microbes, regulated by the same innate immune architecture. A major question has therefore been: how do hosts prevent pathogenic infections while maintaining beneficial microbes? One i...
Thomas C G Bosch,Martin J Blaser,Edward Ruby et al.
Thomas C G Bosch et al.
At a rapid pace, biologists are learning the many ways in which resident microbes influence, and sometimes even control, their hosts to shape both health and disease. Understanding the biochemistry behind these interactions promises to reve...
Elisa Maritan,Andrea Quagliariello,Enric Frago et al.
Elisa Maritan et al.
Millions of years of co-evolution between animals and their associated microbial communities have shaped and diversified the nature of their relationship. Studies continue to reveal new layers of complexity in host-microbe interactions, the...
Innate immunity in Aedes mosquitoes: from pathogen resistance to shaping the microbiota [0.03%]
蚊子的先天免疫系统：从抗病原体到塑造微生物群落
Bretta Hixson,Robin Chen,Nicolas Buchon
Bretta Hixson
Discussions of host-microbe interactions in mosquito vectors are frequently dominated by a focus on the human pathogens they transmit (e.g. Plasmodium parasites and arboviruses). Underlying the interactions between a vector and its transmis...
The roles of ABCB1/P-glycoprotein drug transporters in regulating gut microbes and inflammation: insights from animal models, old and new [0.03%]
ABCB1/P-糖蛋白药物转运体在调节肠道微生物和炎症中的作用：来自动物模型的新旧启示
Lauren Stoeltje,Jenna K Luc,Timothaus Haddad et al.
Lauren Stoeltje et al.
Commensal enteric bacteria have evolved systems that enable growth in the ecologic niche of the host gastrointestinal tract. Animals evolved parallel mechanisms to survive the constant exposure to bacteria and their metabolic by-products. W...
Cereal weevils' antimicrobial peptides: at the crosstalk between development, endosymbiosis and immune response [0.03%]
麦红吸浆虫抗菌肽：发育、内共生和免疫反应之间的交叉点
N Galambos,C Vincent-Monegat,A Vallier et al.
N Galambos et al.
Interactions between animals and microbes are ubiquitous in nature and strongly impact animal physiology. These interactions are shaped by the host immune system, which responds to infections and contributes to tailor the associations with ...
Carla Mulas
Carla Mulas
Cell state transitions are prevalent in biology, playing a fundamental role in development, homeostasis and repair. Dysregulation of cell state transitions can lead to or occur in a wide range of diseases. In this letter, I explore and high...