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期刊名:Philosophical transactions of the royal society b-biological sciences

缩写:PHILOS T R SOC B

ISSN:0962-8436

e-ISSN:1471-2970

IF/分区:4.7/Q1

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共收录本刊相关文章索引6913
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Jennifer J Readshaw,Yan-Jiun Lee,Peter Weigele et al. Jennifer J Readshaw et al.
Bacteriophages (phages), viral predators of bacteria, generate selection pressure that causes bacteria to evolve defence systems. Type I, II and III restriction enzymes cleave incoming non-modified phage DNAs. Phages have evolved to defend ...
Melanie Blokesch Melanie Blokesch
Vibrio cholerae, the causative agent of cholera, has triggered seven pandemics, with the seventh pandemic emerging in 1961. The success of seventh pandemic El Tor (7PET) V. cholerae as a human pathogen is linked to its acquisition of mobile...
Kira Céline Koonce,Jesper Juel Mauritzen,Ida Friberg Hitz et al. Kira Céline Koonce et al.
CRISPR-Cas is an adaptive immune system of bacteria and archaea that protects against foreign genetic elements. In Escherichia coli and Salmonella, CRISPR-Cas is inhibited by the conserved global repressor the histone-like nucleoid structur...
Ville Hoikkala,Haotian Chi,Sabine Grüschow et al. Ville Hoikkala et al.
Most type III CRISPR-Cas systems facilitate immune responses against invading mobile genetic elements such as phages by generating cyclic oligoadenylates (cOAs). Downstream effectors activated by cOAs are typically non-specific proteins tha...
Svetlana Belukhina,Baptiste Saudemont,Florence Depardieu et al. Svetlana Belukhina et al.
Transfer RNA (tRNA) molecules have been recently recognized as widespread targets of bacterial immune systems. Translation inhibition through tRNA cleavage or modification inhibits phage propagation, thereby protecting the bacterial populat...
Adaeze Doris Ojiogu,Jonasz B Patkowski,Xu Kuang et al. Adaeze Doris Ojiogu et al.
Staphylococcus aureus pathogenicity islands (SaPIs) are prototypical members of the phage-inducible chromosomal islands (PICI) family. These elements redirect helper phage capsid assembly to produce smaller capsids, accommodating the satell...
Maisie R Czernuszka,Taoran Fu,Anastasia Kottara et al. Maisie R Czernuszka et al.
Pseudomonas aeruginosa chronic lung infections pose serious challenges for phage therapy due to high between-patient strain diversity and rapid within-patient phenotypic and genetic diversification, necessitating simple predictors of effica...