Association between body-mass index change and lung cancer risk in Korea: nested case-control study [0.03%]
韩国嵌套病例对照研究中BMI变化与肺癌风险的关系
Ji-Woong Nam,Su-Eon Kim,Kyung-Min Lee et al.
Ji-Woong Nam et al.
Background: Previous studies have demonstrated an association between body mass index (BMI) and lung cancer risk, while additional research has found that BMI change affects lung disease. This study aims to investigate th...
PD-1/PD-L1 inhibitors for locally advanced nasopharyngeal carcinoma: a systematic review and meta-analysis based on randomized controlled trials [0.03%]
基于随机对照试验的程序性死亡配体1/程序性死亡受体1抑制剂治疗局部晚期鼻咽癌系统评价和 Meta 分析
Xiaohan Liu,Zhiyuan Shang,Jiawei Gao et al.
Xiaohan Liu et al.
Rural variations in primary care prostate cancer diagnosis and survival: a cohort study using linked Australian primary care electronic medical record data [0.03%]
基于链接的澳大利亚初级保健电子病历数据的前列腺癌诊断和生存的队列研究及农村地区差异性分析
Olivia Wawryk,Ian M Collins,Alex Lee et al.
Olivia Wawryk et al.
Background: Across the state of Victoria, Australia around one-third of residents live in rural areas. There are persisting disparities and poorer prostate cancer outcomes in rural areas compared with metropolitan areas. ...
MRI-based deep learning model for early TACE response prediction in HCC: multicenter validation with biological insights [0.03%]
基于 MRI 的深度学习模型预测肝癌早期 TACE 治疗反应:多中心验证和生物学见解
Mingzhen Chen,Zhongwei Zhao,Lingling Zhou et al.
Mingzhen Chen et al.
Background: Transarterial chemoembolization (TACE) remains a cornerstone treatment for hepatocellular carcinoma (HCC), yet heterogeneous treatment response poses significant clinical challenges. This multicenter study aim...
Modulating tumor interstitial fluid pressure using ultrasound and microbubble therapy: a preclinical study for enhanced drug delivery in cancer treatment [0.03%]
使用超声波和微泡疗法调节肿瘤间质液压力:增强癌症治疗药物输送的临床前研究
Liping Chen,Jianhua Liu,Qiaoli Chen et al.
Liping Chen et al.
Objective: The tumor microenvironment (TME) often hinders effective cancer treatment, where elevated interstitial fluid pressure (IFP) acts as a key barrier to drug penetration. This study investigates the distribution of...
Impact of laparoscopic surgical proficiency on survival outcomes in laparoscopic radical hysterectomy for cervical cancer: a multi-center cohort study [0.03%]
腹腔镜广泛宫颈切除手术熟练度对宫颈癌患者生存结局影响的多中心队列研究
Rongjia Su,Dongjian Yang,Sibang Chen et al.
Rongjia Su et al.
Objective: This study aims to evaluate the impact of gynecologic oncologists' laparoscopic proficiency on survival outcomes in cervical cancer patients. M...
The effect of hope and psychological well-being on quality of life in elderly cancer patients: latent profile analysis [0.03%]
希望和心理幸福感对老年癌症患者生活质量影响的潜类分析
Muhammet Ali Aydın,Veysel Kizilarslan,Muruvvet Emrem et al.
Muhammet Ali Aydın et al.
Background: This study was conducted to examine the effect of hope and psychological well-being on quality of life in elderly cancer patients using latent profile analysis (LPA). ...
Distinct clinical features and epidemiological trends of very early and middle-aged early onset colorectal cancer based on SEER 17 and GBD 2021 data over the past 15 years [0.03%]
基于SEER 17和GBD 2021数据,过去15年非常年轻和中青年早期结直肠癌的临床特征及流行趋势差异分析
Xuanhong Jin,Bingjun Bai,Yang Pan et al.
Xuanhong Jin et al.
Background: The incidence of early-onset colorectal cancer (EOCRC) is rapidly increasing. There may be differences in pathological characteristics and epidemiological trends between different subgroups of EOCRC, which war...
ASAH1-mediated sphingolipid metabolic reprogramming in venetoclax resistance of AML: beyond the monocytic phenotypes [0.03%]
AML中ASAH1介导的鞘脂代谢重编程在维奈克拉耐药中的作用:不局限于单核细胞表型的作用
Lei Zhao,Xinrong Xiang,Ailing Zhong et al.
Lei Zhao et al.
Background: Venetoclax (VEN) in combination with hypomethylating agents has emerged as a pivotal therapy for elderly acute myeloid leukemia (AML) patients ineligible for intensive chemotherapy. However, monocytic AML exhi...
Endoscopic submucosal dissection: a safe alternative to surgical intervention for young patients under 45 years of age with early gastric cancer. ESD vs. surgery in young EGC patients [0.03%]
内镜下黏膜下剥离术可安全替代早期胃癌青年患者(小于45岁)的外科手术治疗。EGC青年患者中ESD与手术的对比研究
Muhammad Haroon Safi,Zhou Hui,Wang Xiaoyong et al.
Muhammad Haroon Safi et al.
Background: Endoscopic submucosal dissection (ESD) is considered a standard therapy for individuals diagnosed with early gastric cancer (EGC) who demonstrate minimal risk of lymph node metastasis. This study aims to compa...