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Inhibition of the ATR-CHK1 signaling pathway sensitizes MCPyV-positive Merkel cell carcinoma to gemcitabine

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Merkel cell carcinoma (MCC) is the primary cutaneous neuroendocrine carcinoma with a mortality rate higher than that of melanoma and other common skin cancers. In the United States, most cases of MCC are positive for Merkel cell polyomavirus (MCPyV), in which ... ...