LncRNA CYP1B1-AS1 as a clinical biomarker exacerbates sepsis inflammatory response via targeting miR- 18a- 5p [0.03%]
长链非编码RNA CYP1B1-AS1通过靶向miR-18a-5p促进脓毒症炎症反应的临床标志物作用机制研究
Lixia Xu,Jingpo Li,Li Li et al.
Lixia Xu et al.
Background: Sepsis, characterized by high morbidity and mortality, necessitates the identification of novel diagnostic and prognostic biomarkers to enhance patient outcomes. Prior research has highlighted the potential cl...
Clinical value of dysregulated miR-125b-5p in severe pneumonia children [0.03%]
异常表达的miR-125b-5p在儿童重症肺炎中的临床价值分析
Meiqin Zhu,Ziyan Lu,Xingjuan Liao et al.
Meiqin Zhu et al.
Background: Severe pneumonia is an important contributor to the high mortality of sick young children. The microRNA-125b-5p (miR-125b-5p), which is widely involved in various cancers, is closely related to a variety of lu...
Dual biological treatments in immune-mediated disorders: a single center experience [0.03%]
自身免疫性疾病双重生物制剂治疗：单中心经验
Oded Shamriz,Elchanan Parnasa,Limor Rubin et al.
Oded Shamriz et al.
Background: Physicians may encounter situations where they need to co-administer omalizumab with non-IgE-targeting monoclonal antibodies. In this study, we share our experience with these dual biologic treatments. ...
Markers of neutrophil activation and some immune and haematological indices in malaria infection during pregnancy [0.03%]
妊娠妇女疟疾感染中中性粒细胞活化标志物和一些免疫及血液学指标的研究
Rebecca Chinyelu Chukwuanukwu,Chioma Esther Agu,Alfred Ehiaghe et al.
Rebecca Chinyelu Chukwuanukwu et al.
Background: Neutrophils are the first responders to pathogen invasion and are important first-line defenders. The defence mechanism of activated neutrophils includes neutrophil extracellular traps (NETs) formation that im...
Fecal microbiota transplantation enhanced the effect of chemoimmunotherapy by restoring intestinal microbiota in LLC tumor-bearing mice [0.03%]
粪便菌群移植通过恢复肠菌屏障功能增强荷LLC瘤小鼠化疗免疫治疗效果
Xinmeng Wang,Qian Geng,Hua Jiang et al.
Xinmeng Wang et al.
Objective: To assess the effect of half-dose chemotherapy (HDC) and standard-dose chemotherapy (SDC) on the intestinal microbiota and to investigate whether fecal microbiota transplantation (FMT) can restore the intestina...
Prediction of Seronegative Hashimoto's thyroiditis using machine learning models based on ultrasound radiomics: a multicenter study [0.03%]
基于超声影像组学的机器学习模型预测无抗体甲状腺自身免疫病桥本氏甲状腺炎：多中心研究
Wenjun Wu,Shengsheng Yao,Daming Liu et al.
Wenjun Wu et al.
Background: Seronegative Hashimoto's thyroiditis is often underdiagnosed due to the lack of antibody markers. Combining ultrasound radiomics with machine learning offers potential for early detection in patients with norm...
Multicenter Study
BMC immunology. 2025 Apr 7;26(1):27. DOI:10.1186/s12865-025-00708-5 2025
Modulating immune responses in alopecia: therapeutic insights and potential targets of antisense oligonucleotides [0.03%]
外用寡核苷酸调节斑秃免疫反应的治疗作用及潜在靶点研究
Shahnaz Begum,Md Jamil Hossain,Insun Kim et al.
Shahnaz Begum et al.
Background: Alopecia areata (AA) are hair loss disorders with distinct pathogenetic mechanisms involving immune dysregulation and microRNA modulation. AA, a T cell-mediated autoimmune disease, is characterized by sudden h...
Correction: Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome [0.03%]
纠正：抗干扰素-γ自身抗体综合征的血清IgE与临床特征和疾病预后的关系
Ni Chen,Hanlin Liang,Siqiao Liang et al.
Ni Chen et al.
Published Erratum
BMC immunology. 2025 Mar 28;26(1):25. DOI:10.1186/s12865-025-00704-9 2025
HTLV-1-infected cells drive the differentiation of monocytes into macrophages in vitro [0.03%]
HTLV-1感染细胞驱动单核细胞分化为巨噬细胞的体外实验
Sabrina de Souza,Guilherme Affonso Melo,Carolina Calôba et al.
Sabrina de Souza et al.
Background: The human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is a chronic inflammatory neurodegenerative disease ...
LINC02363: a potential biomarker for early diagnosis and treatment of sepsis [0.03%]
LINC02363：早期诊断和治疗脓毒症的潜在生物标志物
Linghan Leng,Hao Wang,Yingchun Hu et al.
Linghan Leng et al.
Background: Sepsis remains a leading cause of global morbidity and mortality, yet early diagnosis is hindered by the limited specificity and sensitivity of current biomarkers. ...