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The predictive value of peripheral blood monocytic myeloid-derived suppressor cells for survival and immunotherapy responses in tumor patients [0.03%] 外周血单核细胞源性髓系抑制细胞预测肿瘤患者生存期和免疫治疗反应的价值
Wanying Sheng,Yan Ding,Yuting Su et al. Wanying Sheng et al.
Background and objectives: The identification of affordable and easily accessible indicators to predict overall survival is important for tumor immunotherapy. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous p...
CD28 and CTLA4 polymorphisms associated with ankylosing spondylitis: a study in the context of HLA-B27 [0.03%] CD28和CTLA4的多态性与银屑病关节炎的相关性：在人类白细胞抗原-B27背景下的研究
Kuang-Hui Yu,Gem Huai-Chueh Wu,Chia-Ju Yang et al. Kuang-Hui Yu et al.
Background: The human leukocyte antigen (HLA)-B27 gene is highly associated with ankylosing spondylitis (AS). However, not everyone who carries the HLA-B27 antigen develops AS, indicating that factors beyond the HLA-B27 g...
Evaluation of the effect of the COVID-19 pandemic on depression, anxiety and psychological resilience in patients with primary immunodeficiency [0.03%] 评估COVID-19大流行对原发性免疫缺陷患者抑郁症、焦虑症和心理韧性的影响
Anıl Muştucu,Rümeysa Ayşe Güllülü,Sukru Cekic et al. Anıl Muştucu et al.
Background: Primary immunodeficiencies (PIDs) are a group of diseases that develop as a result of primary or congenital malfunction of the immune system and progress with chronic and/or recurrent bacterial, fungal, protoz...
Prognostic value of the expression of CD27 and CD117 in newly diagnosed multiple myeloma patients [0.03%] CD27和CD117在新诊断的多发性骨髓瘤患者中的预后价值
Xu Si,Jing Zhao,Yichuan Song et al. Xu Si et al.
Objective: The purpose of this study was to investigate the predictive relevance of CD27 and CD117 expression and the prognostic value in newly diagnosed multiple myeloma (NDMM) patients. ...
Dhanushka Dasanayake,Chandima Karunatilake,Chathurika Karunaratne et al. Dhanushka Dasanayake et al.
Background: Alpha gal syndrome (AGS) is a delayed allergy to red meat, due to IgE to galactose-alpha-1,3-galactose (alpha-gal). Sensitization occurs via tick bites. It has been described in the US, Europe, Australia, Japa...
mTORC2 is crucial for regulating the recombinant Mycobacterium tuberculosis CFP-10 protein-induced phagocytosis in macrophages [0.03%] mTORC2在调节巨噬细胞吞噬重组结核杆菌CFP-10蛋白中起关键作用
Xian-Hui Huang,Yu Wang,Liu-Ying Wu et al. Xian-Hui Huang et al.
Mycobacterium tuberculosis (M. tuberculosis, Mtb) is a pathogenic bacterial species in the family Mycobacteriaceae and the causative agent of most cases of tuberculosis. Macrophages play essential roles in defense against invading pathogens...
A comparative analysis of drug-induced kidney injury adverse reactions between cyclosporine and tacrolimus based on the FAERS database [0.03%] 基于FAERS数据库的环孢素与他克莫司肾损害不良反应比较分析
Min Xu,Shanggang Xu,Xueliang Yi Min Xu
Background: This study utilizes the FDA Adverse Event Reporting System (FAERS) database to compare the adverse reaction signals of cyclosporine and tacrolimus, two widely used immunosuppressants, in relation to drug-induc...
Q32.92024 Comparative Study BMC immunology. 2025 May 2;26(1):35. DOI:10.1186/s12865-025-00714-7 2025
Michele Matsuoka,Salim Abraham Soria,Julien Rodrigues Pires et al. Michele Matsuoka et al.
This review comprehensively explores the intricate immune responses within the oral cavity, emphasizing the pivotal role of saliva in maintaining both oral and systemic health. Saliva, a complex biofluid, functions as a dynamic barrier agai...
Incidence of severe adverse events in cancer patients after treatment with immune-checkpoint inhibitors during the COVID- 19 pandemic [0.03%] 新冠疫情期间肿瘤患者接受免疫检查点抑制剂治疗后发生严重不良事件的发病率
Sakiko Kimura,Hiroo Katsuya,Chiho Nakashima et al. Sakiko Kimura et al.
Immune-checkpoint inhibitors (ICIs) can cause inflammation and immune-related adverse events (irAEs). Although irAEs may be caused by dysregulation of cytokines, the impact of various COVID- 19-related factors on expression of ICI-related A...
LncRNA CYP1B1-AS1 as a clinical biomarker exacerbates sepsis inflammatory response via targeting miR- 18a- 5p [0.03%] 长链非编码RNA CYP1B1-AS1通过靶向miR-18a-5p促进脓毒症炎症反应的临床标志物作用机制研究
Lixia Xu,Jingpo Li,Li Li et al. Lixia Xu et al.
Background: Sepsis, characterized by high morbidity and mortality, necessitates the identification of novel diagnostic and prognostic biomarkers to enhance patient outcomes. Prior research has highlighted the potential cl...