Dexamethasone priming enhances stemness and immunomodulatory property of tissue-specific human mesenchymal stem cells [0.03%]
地塞米松预处理增强组织特异性人间充质干细胞的干性和免疫调节特性
Sonali Rawat,Vatsla Dadhwal,Sujata Mohanty
Sonali Rawat
Background: Human Mesenchymal Stem Cells (hMSCs) represent a promising cell source for cell-based therapy in autoimmune diseases and other degenerative disorders due to their immunosuppressive, anti-inflammatory and regen...
Comparative transcriptome analysis uncovers cell wall reorganization and repressed cell division during cotton fiber initiation [0.03%]
比较转录组学分析揭示了棉花纤维起始过程中细胞壁的重新组织以及细胞分裂受到抑制
Wenyuan Liu,Yanjia Lv,Xiaoyue Li et al.
Wenyuan Liu et al.
Background: Tetraploid cotton plants serve as prime natural fiber source for the textile industry. Although various omics studies have revealed molecular basis for fiber development, a better understanding of transcriptio...
Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype [0.03%]
MSX1单倍不足改变Pax9缺陷的心血管表型
Ramada R Khasawneh,Ralf Kist,Rachel Queen et al.
Ramada R Khasawneh et al.
Background: Successful embryogenesis relies on the coordinated interaction between genes and tissues. The transcription factors Pax9 and Msx1 genetically interact during mouse craniofacial morphogenesis, and mice deficien...
Identification of reference genes for gene expression studies among different developmental stages of murine hearts [0.03%]
小鼠心脏不同发育阶段基因表达研究中的参照基因鉴定
Jie Ren,Ningning Zhang,Xiangjie Li et al.
Jie Ren et al.
Background: Real-time quantitative polymerase chain reaction (RT-qPCR) is a widely-used standard assay for assessing gene expression. RT-qPCR data requires reference genes for normalization to make the results comparable....
Majesta J Roth,Roger A Moorehead
Majesta J Roth
The miR-200 family of microRNAs plays a significant role in inhibiting mammary tumor growth and progression, and its members are being investigated as therapeutic targets. Additionally, if future studies can prove that miR-200s prevent mamm...
Development of the indirect flight muscles of Aedes aegypti, a main arbovirus vector [0.03%]
蚊子主要的虫媒病媒介肌肉的发育飞行间接肌肉埃及伊蚊
Antonio Celestino-Montes,Salvador Hernández-Martínez,Mario Henry Rodríguez et al.
Antonio Celestino-Montes et al.
Background: Flying is an essential function for mosquitoes, required for mating and, in the case of females, to get a blood meal and consequently function as a vector. Flight depends on the action of the indirect flight m...
Wdpcp regulates cellular proliferation and differentiation in the developing limb via hedgehog signaling [0.03%]
WDPCP通过 Hedgehog 信号通路调控发育中肢体的细胞增殖和分化
Mark T Langhans,Jingtao Gao,Ying Tang et al.
Mark T Langhans et al.
Background: Mice with a loss of function mutation in Wdpcp were described previously to display severe birth defects in the developing heart, neural tube, and limb buds. Further characterization of the skeletal phenotype ...
Changes in the expression levels of elastic fibres in yak lungs at different growth stages [0.03%]
不同生长阶段牦牛肺弹性纤维表达水平变化
Jingyi Li,Xiangqiong Meng,Lihan Wang et al.
Jingyi Li et al.
Background: Yaks have a strong adaptability to the plateau environment, which can be attributed to the effective oxygen utilization rate of their lung tissue. Elastic fibre confers an important adaptive structure to the a...
The migratory pathways of the cells that form the endocardium, dorsal aortae, and head vasculature in the mouse embryo [0.03%]
小鼠胚胎心内膜、背主动脉和头部血管形成细胞的迁移路径
C Collart,A Ciccarelli,K Ivanovitch et al.
C Collart et al.
Background: Vasculogenesis in amniotes is often viewed as two spatially and temporally distinct processes, occurring in the yolk sac and in the embryo. However, the spatial origins of the cells that form the primary intra...
Knockdown of hspg2 is associated with abnormal mandibular joint formation and neural crest cell dysfunction in zebrafish [0.03%]
斑马鱼HSPG2基因敲降导致下颌关节发育异常及神经嵴细胞功能障碍
Barbara S Castellanos,Nayeli G Reyes-Nava,Anita M Quintana
Barbara S Castellanos
Background: Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in cartilage formation, cell adhesion, and basement membrane stability. Mutations in HSPG2 have be...