Comparative metabolic fingerprinting of Gentiana rhodantha from different geographical origins using LC-UV-MS/MS and multivariate statistical analysis [0.03%]
基于LC-UV-MS/MS和多变量统计分析的兔耳金梅花不同产地的代谢指纹对比研究
Yu Pan,Ji Zhang,Tao Shen et al.
Yu Pan et al.
Backgrounds: Gentiana rhodantha, a rich source of iridoids and polyphenols, is a traditional ethnomedicine widely used in China. Metabolic fingerprinting based on a LC-UV-MS/MS method was applied to explore the chemical m...
Comparative Study
BMC biochemistry. 2015 Mar 28:16:9. DOI:10.1186/s12858-015-0038-5 2015
Identification of fragments from Autographa californica polyhedrin protein essential for self-aggregation and exogenous protein incorporation [0.03%]
识别编码家蚕核多角体病毒聚基蛋白的片段其对于自主聚集和外源蛋白质包涵体形成是必需的
Alicia Sampieri,Agustín Luz-Madrigal,Jesus Zepeda et al.
Alicia Sampieri et al.
Background: Baculoviruses are widely used for the production of recombinant proteins, biopesticides and as gene delivery systems. One of the viral forms called polyhedra has been recently exploited as a scaffold system to...
Human DNA-binding peptidyl-prolyl cis/trans isomerase Par14 is cell cycle dependently expressed and associates with chromatin in vivo [0.03%]
人DNA结合肽基-脯氨酰顺/反异构酶Par14的表达依赖细胞周期并且能够在体内与染色质相连
Akuma D Saningong,Peter Bayer
Akuma D Saningong
Background: Par14, a member of the parvulin family of peptidyl-prolyl cis-trans isomerases that is involved in rRNA processing, microtubule formation and the glucose metabolism and has been suggested to play a role in chr...
Digested wheat gluten inhibits binding between leptin and its receptor [0.03%]
低热量饮食中麦胶蛋白的代谢产物能抑制瘦素与其受体的结合
Tommy Jönsson,Ashfaque A Memon,Kristina Sundquist et al.
Tommy Jönsson et al.
Background: Leptin resistance is considered a primary risk factor for obesity. It has been hypothesized that dietary cereal grain protein could cause leptin resistance by preventing leptin from binding to its receptor. No...
Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells [0.03%]
短链脂肪酸盐抑制组蛋白去乙酰化酶并抑制拓扑异构酶抑制剂诱导的DNA双链断裂修复具有细胞类型特异性
Liping Li,Youxiang Sun,Jiangqin Liu et al.
Liping Li et al.
Background: Histone deacetylase inhibitors (HDACi's) are emerging as promising anticancer drugs alone or in combination with chemotherapy or radiotherapy agents. Previous research suggests that HDACi's have a high degree ...
Mechano-growth factor accelerates the proliferation and osteogenic differentiation of rabbit mesenchymal stem cells through the PI3K/AKT pathway [0.03%]
机械生长因子通过PI3K/AKT途径促进兔间充质干细胞的增殖和成骨分化
Yanxiang Tong,Wei Feng,Yimin Wu et al.
Yanxiang Tong et al.
Background: Mesenchymal stem cells (MSCs) can differentiate into chondroblasts, adipocytes, or osteoblasts under appropriate stimulation. Mechano-growth factor (MGF) reportedly displays a neuroprotective effect in cerebra...
Folding and self-association of atTic20 in lipid membranes: implications for understanding protein transport across the inner envelope membrane of chloroplasts [0.03%]
蛋白在脂质膜中的折叠和自聚对其穿越类囊体内部被膜的转运的意义
James H Campbell,Tuan Hoang,Masoud Jelokhani-Niaraki et al.
James H Campbell et al.
Background: The Arabidopsis thaliana protein atTic20 is a key component of the protein import machinery at the inner envelope membrane of chloroplasts. As a component of the TIC complex, it is believed to form a preprotei...
DNA binding reduces the dissociation rate of STAT1 dimers and impairs the interdimeric exchange of protomers [0.03%]
DNA结合降低了STAT1二聚体的解离速率并阻碍了单体在二聚体之间的交换
Theresa Riebeling,Julia Staab,Christoph Herrmann-Lingen et al.
Theresa Riebeling et al.
Background: A shift between two dimer conformations has been proposed for the transcription factor STAT1 (signal transducer and activator of transcription 1) which links DNA binding of the parallel dimer to tyrosine depho...
Protein expression, characterization and activity comparisons of wild type and mutant DUSP5 proteins [0.03%]
DUSP5野生型和突变蛋白的表达、鉴定及活性比较
Jaladhi Nayak,Adam J Gastonguay,Marat R Talipov et al.
Jaladhi Nayak et al.
Background: The mitogen-activated protein kinases (MAPKs) pathway is critical for cellular signaling, and proteins such as phosphatases that regulate this pathway are important for normal tissue development. Based on our ...
ADP-Ribosylargininyl reaction of cholix toxin is mediated through diffusible intermediates [0.03%]
胆固醇毒素的ADP核糖基化精氨酸反应通过可扩散的中间体介导
Vicky M-H Sung,Chia-Lun Tsai
Vicky M-H Sung
Background: Cholix toxin is an ADP-ribosyltransferase found in non-O1/non-O139 strains of Vibrio cholera. The catalytic fragment of cholix toxin was characterized as a diphthamide dependent ADP-ribosyltransferase. ...