Application of WST-8 based colorimetric NAD(P)H detection for quantitative dehydrogenase assays [0.03%]
基于WST-8的比色NAD(P)H检测法在定量脱氢酶活性测定中的应用研究
Kamonwan Chamchoy,Danaya Pakotiprapha,Pornpan Pumirat et al.
Kamonwan Chamchoy et al.
Background: The reduction of tetrazolium salts by NAD(P)H to formazan product has been widely used to determine the metabolic activity of cells, and as an indicator of cell viability. However, the application of a WST-8 b...
Association of TM6SF2 rs58542926 gene polymorphism with the risk of non-alcoholic fatty liver disease and colorectal adenoma in Chinese Han population [0.03%]
TM6SF2基因多态性与中国汉族人非酒精性脂肪肝及结肠腺瘤发病风险的关联研究
Yuan Li,Shousheng Liu,Yuqiang Gao et al.
Yuan Li et al.
Background: Genetic factors affect the risk of non-alcoholic fatty liver disease (NAFLD) and colorectal adenoma (CRA) importantly. Transmembrane protein 6 superfamily member 2 (TM6SF2) rs58542926 is a significant genetic ...
The active role of the transcription factor Sp1 in NFATc2-mediated gene regulation in pancreatic cancer [0.03%]
转录因子Sp1在NFATc2介导的基因调控中发挥积极作用——胰腺癌中的作用机制研究
Manuela Malsy,Bernhard Graf,Katrin Almstedt
Manuela Malsy
Background: Adenocarcinoma of the pancreas is one of the most aggressive tumor diseases affecting the human body. The oncogenic potential of pancreatic cancer is mainly characterized by extremely rapid growth triggered by...
Role of the highly conserved G68 residue in the yeast phosphorelay protein Ypd1: implications for interactions between histidine phosphotransfer (HPt) and response regulator proteins [0.03%]
酵母磷酸传递蛋白Ypd1高度保守的G68残基的作用：对组氨酸磷酸转移(HPt)和响应调节蛋白之间相互作用的意义
Emily N Kennedy,Skyler D Hebdon,Smita K Menon et al.
Emily N Kennedy et al.
Background: Many bacteria and certain eukaryotes utilize multi-step His-to-Asp phosphorelays for adaptive responses to their extracellular environments. Histidine phosphotransfer (HPt) proteins function as key components ...
Up-regulation of DcR3 in microbial toxins-stimulated HUVECs involves NF-κB signalling [0.03%]
微生物毒素刺激的HUVEC中DCR3上调与NF-κB信号转导有关
Yanqiang Hou,Dongyu Liang,Yang Liu et al.
Yanqiang Hou et al.
Background: Sepsis is a severe condition characterised by the body's systemic inflammatory response to infection. The specific sepsis-related biomarkers should be used in clinical diagnosis, therapeutic response monitorin...
Soluble expression of recombinant midgut zymogen (native propeptide) proteases from the Aedes aegypti Mosquito Utilizing E. coli as a host [0.03%]
利用大肠杆菌表达体系可溶性表达登革热病毒媒介蚊虫埃及伊蚊肠道酶原类蛋白酶基因产物的研究
James T Nguyen,Jonathan Fong,Daniel Fong et al.
James T Nguyen et al.
Background: Studying proteins and enzymes involved in important biological processes in the Aedes aegypti mosquito is limited by the quantity that can be directly isolated from the mosquito. Adding to this difficulty, dig...
Identification of the major diacylglycerol acyltransferase mRNA in mouse adipocytes and macrophages [0.03%]
小鼠脂肪细胞和巨噬细胞中鉴定主要的二酰基甘油酰基转移酶mRNA
Heping Cao
Heping Cao
Background: Triacylglycerols (TAGs) are the major form of energy storage in eukaryotes. Diacylglycerol acyltransferases (DGATs) catalyze the final and rate-limiting step of TAG biosynthesis. Mammalian DGATs are classified...
Purification and characterization of cysteine protease from miswak Salvadora persica [0.03%]
来自Miswak（救世树）的半胱氨酸蛋白酶的提纯与表征
Wesam H Abdulaal
Wesam H Abdulaal
Background: Generally, proteases in medicinal plants had different therapeutic effects such as anti-inflammatory effect; modulate the immune response and inhibitory effect toward tumor growth. In this study, protease was ...
Samaneh Miraee-Nedjad,Paul F G Sims,Jean-Marc Schwartz et al.
Samaneh Miraee-Nedjad et al.
Background: Islet amyloid polypeptide (IAPP) or amylin deposits can be found in the islets of type 2 diabetes patients. The peptide is suggested to be involved in the etiology of the disease through formation of amyloid d...
Structure and function of a lignostilbene-α,β-dioxygenase orthologue from Pseudomonas brassicacearum [0.03%]
来源于假单胞菌Pseudomonas brassicacearum木脂茋-α，β-双氧化酶同系物的结构与功能研究
Peter C Loewen,Jacek Switala,James P Wells et al.
Peter C Loewen et al.
Background: Stilbene cleaving oxygenases (SCOs), also known as lignostilbene-α,β-dioxygenases (LSDs) mediate the oxidative cleavage of the olefinic double bonds of lignin-derived intermediate phenolic stilbenes, yieldin...