Gangshun Yi,Dimitrios Mamalis
Gangshun Yi
Inflammageing and clonal haematopoiesis interplay and their impact on human disease [0.03%]
炎症性衰老与克隆型造血的相互作用及其对人体健康的影响
George Hajishengallis,Triantafyllos Chavakis
George Hajishengallis
Clonal haematopoiesis of indeterminate potential (CHIP) is an ageing-related condition associated with a substantial fraction of circulating leukocytes having descended from a single somatically mutated haematopoietic stem cell (HSC). CHIP ...
Sandra Duharcourt
Sandra Duharcourt
Progress in stem cell-based embryo models and their applications in developmental biology and biomedicine [0.03%]
基于干细胞的胚胎模型研究进展及其在发育生物学和生物医学中的应用
Hao Wu,Hongmei Wang
Hao Wu
Human stem cell-based embryo models (hSCBEMs) are emerging as powerful tools in biomedical research owing to their ability to recapitulate the cellular, molecular and structural features of human embryos. These models offer new opportunitie...
Organization of replicated chromosomes by DNA loops and sister chromatid cohesion [0.03%]
通过DNA环和姐妹染色单体黏连实现重复染色体的组织结构
Fena Ochs,Daniel W Gerlich
Fena Ochs
Cohesin is a key regulator of three-dimensional genome organization, contributing to gene regulation, recombination, DNA repair and chromosome segregation. Like other members of the evolutionary conserved structural maintenance of chromosom...
Biology and therapeutic potential of extracellular vesicle targeting and uptake [0.03%]
细胞外囊泡靶向和摄取的生物学及治疗潜力
Léa Ripoll,Antje M Zickler,Pieter Vader et al.
Léa Ripoll et al.
Extracellular vesicles (EVs) have gained significant attention owing to their role in pathophysiological processes and potential as therapeutic tools. EVs are small vesicles (30 nm-5 µm) containing specific cargo (proteins, nucleic acids a...
Advancing single-cell omics and cell-based therapeutics with quantum computing [0.03%]
利用量子计算推进单细胞组学和基于细胞的治疗技术
Aritra Bose,Kahn Rhrissorrakrai,Filippo Utro et al.
Aritra Bose et al.
The generation of highly accurate models of behaviours of individual cells and cell populations through integration of high-resolution assays with advanced computational tools would transform precision medicine. Recent breakthroughs in sing...
Kim Baumann
Kim Baumann
Eytan Zlotorynski
Eytan Zlotorynski