Steffen Vanneste,Yuanrong Pei,Jiří Friml
Steffen Vanneste
The phytohormone auxin is a major signal coordinating growth and development in plants. The variety of its effects arises from its ability to form local auxin maxima and gradients within tissues, generated through directional cell-to-cell t...
Oliver Daumke,Martin van der Laan
Oliver Daumke
Mitochondria display intricately shaped deep invaginations of the mitochondrial inner membrane (MIM) termed cristae. This peculiar membrane architecture is essential for diverse mitochondrial functions, such as oxidative phosphorylation or ...
Kim Baumann
Kim Baumann
Caroline Barranco
Caroline Barranco
Maïwen Caudron-Herger
Maïwen Caudron-Herger
An evolving landscape of PRC2-RNA interactions in chromatin regulation [0.03%]
染色质调节中PRC2-RNA相互作用的演变景观
Rodrigo Aguilar,Michael Rosenberg,Vered Levy et al.
Rodrigo Aguilar et al.
A major unsolved problem in epigenetics is how RNA regulates Polycomb repressive complex 2 (PRC2), a complex that trimethylates histone H3 Lys27 (H3K27me3) to form repressive chromatin. Key questions include how PRC2 binds RNA in vivo and w...
Neurons whisper, tissues respond: neurons as orchestrators of stress responses [0.03%]
神经元低语，组织响应：压力反应的神经元协调者
Evandro A De-Souza
Evandro A De-Souza
Mia T Levine
Mia T Levine
Eikan Mishima,Toshitaka Nakamura,Sebastian Doll et al.
Eikan Mishima et al.
Ferroptosis is a necrotic, non-apoptotic cell death modality triggered by unrestrained iron-dependent lipid peroxidation. By unveiling the regulatory mechanisms of ferroptosis and its relevance to various diseases, research over the past de...
p53-regulated non-apoptotic cell death pathways and their relevance in cancer and other diseases [0.03%]
由P53调控的非凋亡细胞死亡途径及其在癌症和其它疾病中的意义
Yanqing Liu,Brent R Stockwell,Xuejun Jiang et al.
Yanqing Liu et al.
Programmed cell death is a mechanism that is crucial for numerous physiological and pathological processes. Whereas p53-mediated apoptosis is a major cell death pathway in cancer, accumulating evidence indicates that p53 also has crucial ro...