Early life experiences, the neural epigenome and affective disorder risk [0.03%]
早期经历、神经环状染色体和情绪障碍风险
Ashley M Cunningham,Ian Maze
Ashley M Cunningham
Early life stress shapes brain development during sensitive developmental windows through persistent epigenomic changes that influence gene regulation, neural circuit maturation and susceptibility to neuropsychiatric disorders. Evidence fro...
Bradley B Jamieson,Johannes Kohl
Bradley B Jamieson
Most mammalian offspring are born helpless and depend on sustained parental care for survival, making caregiving one of the most conserved and essential behavioural repertoires in mammals. Yet infant-directed behaviours can be remarkably va...
Danny Adrian Spampinato,Annibale Antonioni,Egidio D&#x;Angelo et al.
Danny Adrian Spampinato et al.
Cerebellar rhythms provide frequency-specific support for motor, cognitive and affective functions. These oscillations are not epiphenomenal but rather dynamically regulated, spatially organized control signals that contribute to the coordi...
Bart J L Eggen,Susanne M Kooistra
Bart J L Eggen
Microglia, the resident macrophages of the CNS parenchyma, are recognized as highly plastic, transcriptionally diverse cells whose phenotypes are moulded by development, region, sex, age, genotype and environment. Advances in single-cell an...
Andrea I Luppi,Helena M Gellersen,Lorina Naci et al.
Andrea I Luppi et al.
Carmen Sandi,Mary Kay Lobo,Fiona Hollis et al.
Carmen Sandi et al.
Cognition and behaviour arise from computations in neural circuits, which can differ in their readiness for recruitment or in the computations and behavioural outputs that they generate. Mitochondria contribute to both circuit properties an...
Sian Lewis
Sian Lewis
Driving neuronal apoptosis [0.03%]
驱动神经元凋亡
Darran Yates
Darran Yates