Bio-Designed Carboxymethyl Chitosan/Polyvinyl Alcohol Hydrogel Containing Alpha-Tocopherol as a Three-Dimensional Wound Dressing, In Vitro and In Vivo Study [0.03%]
一种含有维生素E的仿生设计的脱乙酰壳多糖/聚乙烯醇水凝胶三维人造皮肤及其体内外研究
Ghazaleh Naghizadeh Hanjani,Shiva Irani,Fereshteh Sharifi et al.
Ghazaleh Naghizadeh Hanjani et al.
Chitosan-based hydrogels have highly attractive potential for designing wound dressing production. To promote wound healing, it is admirable to develop three-dimensional (3D) multi-biological functional polyvinyl alcohol/carboxymethyl chito...
Whole Transcriptomic Identification and Characterization of Potential ceRNA Regulatory Networks in Perirenal Adipose Tissue of Type-2-Diabetic Mellitus SD Rats With Diabetic Nephropathy [0.03%]
链锁性糖尿病肾病大鼠周围型脂肪组织中ceRNA调控网络的转录组学研究
Yang Li,Yan Zhao,Rou Shi et al.
Yang Li et al.
This study induced diabetic nephropathy (DN) in rats, analyzing perirenal adipose tissue (PRAT) via whole transcriptome sequencing to identify key mRNAs in DN pathogenesis. Type-2 diabetes was induced in SD rats, evaluating metabolic and re...
Bioreactor pH Control System Using Interval Type-2 Fuzzy PID Controller [0.03%]
采用区间二型模糊PID控制器的生物反应器PH控制系统
Songyang An,Haotian Xu,Jizheng Zhong et al.
Songyang An et al.
In cell culture, maintaining a stable and optimal pH level is critical for ensuring proper cellular growth. This study presents the design of a pH control system specifically tailored for this application, utilizing an algorithm that integr...
Single-Cell Transcriptomic Analysis Reveals Hair Cell-Specific Molecular Responses to Polystyrene Nanoplastics in a Zebrafish Embryo Model [0.03%]
单细胞转录组分析揭示了聚苯乙烯纳米塑料在斑马鱼胚胎模型中对毛细胞的特异性分子反应
Hyeon Mi Sung,Seok Hyun Kim,Eun Jung Kwon et al.
Hyeon Mi Sung et al.
Polystyrene nanoplastics (PSNPs) have emerged as pervasive environmental pollutants with potential toxicological effects on aquatic ecosystems. Their small size, hydrophobicity, and structural stability enable penetration into biological ti...
Computational Modeling and Validation of Predicted Diagnostic Peptides for Crimean-Congo's Disease [0.03%]
克里米亚-刚果疾病的预测诊断肽的计算建模与验证
Elijah Kolawole Oladipo,Sola Peter Ogunmodede,Gladys Ayodele Adigun et al.
Elijah Kolawole Oladipo et al.
The absence of prompt and reliable diagnosis limits the eradication of Crimean-Congo's hemorrhagic fever (CCHF) caused by Hyalomma. Although there have been several recent developments in different points of care and diagnosis, there has be...
TIGAR Alleviates Acute Pancreatitis by Suppressing Glycolysis Through the LAMP2/PI3K/Akt Axis [0.03%]
LAMP2/PI3K/Akt信号轴抑制糖酵解缓解急性胰腺炎的新机制-TIGAR诱导的非凋亡细胞死亡
Dan Xie,Chiwen Bu
Dan Xie
Acute pancreatitis (AP) is a prevalent inflammatory disorder of the pancreas, with emerging evidence implicating aberrant acinar cell glycolysis in disease progression. Although TIGAR (TP53-induced glycolysis and apoptosis regulator), a key...
Improved Lovastatin Production via Targeted Medium Supplementation in Aspergillus terreus [0.03%]
通过目标培养基补充法改良土曲霉lovastatin产量
Maryam Javanpour,Ramtin Vamenani,Ethan Brister
Maryam Javanpour
Lovastatin is a clinically crucial cholesterol-lowering agent produced by Aspergillus terreus; however, its commercial biosynthesis remains limited due to suboptimal fermentation conditions. This study addresses the challenge of evaluating ...
Construction of Hollow Mesoporous Selenium Loaded With Carboplatin and Clacked With Bevacizumab-Functionalized Albumin Nanoparticles for HER2+ Lung Cancer [0.03%]
一种用于HER2阳性肺癌的中空多孔硒载卡铂并结合贝伐单抗包被的人血白蛋白纳米颗粒的构建方法
Weibin Luo,Zhengyuan Yang,Shihua Gao et al.
Weibin Luo et al.
Lung carcinoma is one of the most severe types of cancer, characterized by a dismal prognosis and low overall survival rate, primarily due to late diagnosis and the ineffectiveness of standard treatments. Hence, this study aimed to develop ...
Production and Formulation of Alcanivorax borkumensis SK2 Cell Powders for Marine Oil Spill Bioremediation [0.03%]
海洋溢油生物修复用Alcanivorax borkumensis SK2细胞粉的生产和配方研究
Élisabeth Perreault,Denis Groleau,Patrick Vermette
Élisabeth Perreault
Oil spills pose severe threats to marine ecosystems and coastal communities. Alcanivorax borkumensis SK2, a marine bacterium with superior hydrocarbon-degrading capabilities, emerges as a promising agent for bioremediation. This study ident...
Lactobacillus Cocktail Potentially Alleviated the Toxic Effects of Zearalenone in Mice Receiving a Zearalenone-Contaminated Diet [0.03%]
枯草芽孢杆菌混合物可减轻玉米赤霉烯酮污染饮食对小鼠的毒性作用
Delaram Hassani,Golnar Kermani,Fatemeh Samizadeh Mashhadi et al.
Delaram Hassani et al.
Zearalenone (ZEN) is a prevalent immunosuppressive and estrogenic metabolite synthesized by certain species of Fusarium fungi. This mycotoxin has a propensity to contaminate food and feed products, leading to immune system suppression and r...