In Vitro Evaluation of Acetaminophen as a Repurposed Anti-Influenza Virus Agent [0.03%]
对乙酰氨基酚作为抗流感病毒再定位药物的体外评价研究
Surojit Sadhu,Sanket Bapat,Pinky Singh et al.
Surojit Sadhu et al.
Influenza remains a major global health concern, characterized by recurrent seasonal outbreaks and the persistent threat of pandemic strains. Although vaccines and antivirals are available, their effectiveness is often compromised by antige...
Constructing Haloarchaeal MVA Pathway in Serratia marcescens for Synthesis of Ocimene [0.03%]
构建盐杆菌MVA途径以产生月桂烯应用于业拉环菌中
Songsong Yao,Di Liu,Long Wang et al.
Songsong Yao et al.
Ocimene, a valuable monoterpene with applications in agriculture, pharmaceuticals, and fragrances, is challenging to produce at high yields using traditional microbial platforms such as Escherichia coli and Saccharomyces cerevisiae due to m...
Biosynthesis and Characterization of Zinc Oxide-Doped Selenium Nanocomposite Conjugated With l-Asparaginase Against Human Hepatoma Cell Line [0.03%]
用硒纳米复合物掺杂的氧化锌共轭l-天冬氨酶对人类肝细胞的研究及表征
G Baskar,K Keerthana,A Supriya et al.
G Baskar et al.
Nanocarriers have emerged as promising systems for improving drug-delivery efficiency and advancing diagnostic strategies in cancer treatment. l-asparaginase has well-established antitumor and anti-leukemic properties, but its therapeutic p...
Amylase Production From Potato Peels by Bacillus sp. Under Improved Culture Conditions [0.03%]
优化培养条件下假单胞菌种从土豆皮中提取α-淀粉酶的研究
Sourav Agarwal,Priya Mitra,Shreosee Ghosh et al.
Sourav Agarwal et al.
Amylase, an enzyme with significant industrial applications, can be produced sustainably and economically using agricultural waste. This study investigates amylase production from Bacillus species utilizing potato peel substrates, aiming to...
An In Silico Study of Resveratrol Derivatives as Dual Inhibitors of Cyclooxygenase-2 (COX-2) and 5-Lipoxygenase (5-LOX) in Cancer Therapy [0.03%]
白藜芦醇衍生物作为癌症治疗中环氧化酶-2(COX-2)和5-脂氧合酶(5-LOX)双重抑制剂的计算研究
Sayali Doiphode,Payel Ghosh,K Venkateswara Swamy et al.
Sayali Doiphode et al.
Chronic inflammation plays a crucial role in cancer initiation, progression, and metastasis, with cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) often co-expressed and upregulated in tumor-associated inflammatory microenvironments. Res...
Comparative Study on Quantitative Analysis and In Vitro Antioxidant Potential of Leaf and Stem of Salvadora oleoides (Decne.) and Optimization of Flavonoids Using RSM [0.03%]
盐生狼尾草叶和茎的定量分析及体外抗氧化潜力的比较研究及利用RSM优化黄酮类化合物
Nidhi Varshney,Devendra Singh,Pracheta Janmeda
Nidhi Varshney
This study quantitatively estimated bioactive compounds in leaves and stem of Salvadora oleoides (S. oleoides) and evaluated in vitro antioxidant activity of aqueous and organic extracts (petroleum ether, benzene, chloroform, ethyl acetate,...
High-Throughput Virtual Screening of Phytochemicals From Indian Medicinal Plants for the Identification of Potential Inhibitors Against NS2B-NS3 Protease of Dengue Virus [0.03%]
用于筛选印度草药植物中针对登革热病毒NS2B-NS3蛋白酶的潜在抑制剂的高通量虚拟筛选研究
Kandavelmani Angamuthu,Saranya Nallusamy,Poongodi Thangavel et al.
Kandavelmani Angamuthu et al.
Dengue is an acute mosquito-borne viral infection that has become a major health problem worldwide in recent years. Currently, no specific antiviral therapies are available to treat dengue fever. Every year, an enormous number of deaths are...
1-Alkyl-1H-Benzimidazolium Sulfonates as Non-Competitive Inhibitors of Polyphenol Oxidase [0.03%]
1-烷基-1H-苯并咪唑
Adem Ergün,Kübra Çikrikci,Nahit Gençer et al.
Adem Ergün et al.
Polyphenol oxidase (PPO) has been the subject of many inhibition studies due to its presence in many species, causing enzymatic browning in fruits and vegetables, and its pigmentation role in mammalian species. In the present study, the inh...
miR-16-5p Attenuated Airway Inflammation and Pulmonary Fibrosis of Asthma Rats by Regulating the TGF-β1/Smad3 Signaling [0.03%]
miR-16-5p通过调节TGF-β1/Smad3信号通路减轻哮喘大鼠气道炎症和肺纤维化
Weiwei She,Tianshou Sun,Chengfeng Long et al.
Weiwei She et al.
Bronchial asthma is a significant inflammatory disorder impacting the airways. While current therapeutic interventions manage these symptoms, they do not offer a cure for the condition. Emerging research indicates that specific microRNAs (m...
Polyethylene Carboxylates Synthesized via Statistical Optimization: A Biocompatible Polymer Scaffold for Bioactive Conjugation [0.03%]
基于统计优化的聚乙烯羧酸酯的合成：用于生物活性接枝的生物相容性聚合物骨架
Vinay Sagar Verma,Rajesh Choudhary,Amit Alexander et al.
Vinay Sagar Verma et al.
The study aimed to synthesize and evaluate polyethylene carboxylates (PECs) as a biocompatible polymer for drug delivery. The synthesis of PECs has been achieved by making slight modifications through statistical optimization in reaction co...