Wnt signalling pathway dysfunction in non-obstructive azoospermia: identifying key genes and potential therapeutic targets [0.03%]
非梗阻性无精子症中Wnt信号通路功能障碍：识别关键基因和潜在治疗靶点
Xiaobin Guo,Xiaohong Li,Taisen Pang et al.
Xiaobin Guo et al.
This study aimed to investigate the involvement of the Wnt signalling pathway in the pathogenesis of non-obstructive azoospermia (NOA) and to identify potential diagnostic and therapeutic targets. We obtained the gene expression profiles of...
Ubiquitin-mediated degradation of RPN13 promotes porcine sperm capacitation and sperm-zona pellucida binding [0.03%]
泛素介导的RPN13降解促进猪精子获能和精子-卵泡颗粒结合
Zhiwei Yao,Lipeng Cao,Jie Wang et al.
Zhiwei Yao et al.
Sperm capacitation involves biochemical and functional changes necessary for fertilization. The ubiquitin-proteasome system (UPS) regulates protein turnover, but the roles of proteasomal receptors during capacitation remain unclear. This st...
The effects of circadian rhythm on reproductive functions - CORRIGENDUM [0.03%]
昼夜节律对生殖功能的影响-CORRIGENDUM
Seda Karabulut,Lima Oria
Seda Karabulut
Published Erratum
Zygote (Cambridge, England). 2026 Aug 4:1-6. DOI:10.1017/S0967199426100434 2026
Investigating the impact of psychopharmacological agents on spermatozoa parameters, genomic integrity and chromatin architecture - CORRIGENDUM [0.03%]
心理药理学药物对精子参数、基因组完整性和染色质结构的影响的研究——勘误表
Uğurcan Altiok,Seda Karabulut,Oya Korkmaz et al.
Uğurcan Altiok et al.
Published Erratum
Zygote (Cambridge, England). 2026 Aug 3:1. DOI:10.1017/S0967199426100604 2026
Establishing a safe and effective cleaning method for PDMS devices derived from 3D-printed resin moulds in embryo production [0.03%]
基于3D打印树脂模具的PDMS装置在胚胎生产中的安全有效清洗方法建立
Patricia Kubo Fontes,Roksan Franko,Giuliana de Avila Ferronato et al.
Patricia Kubo Fontes et al.
Dynamic systems for in vitro embryo production (IVEP) have long been sought to allow a higher resemblance to the physiological conditions of the oviduct and uterus. Although significant progress has been demonstrated in the microfluidic fie...
The interruption of the treatment with naproxen restored the C57BL/6 ovulation rate [0.03%]
萘普生治疗的中断恢复C57BL / 6的排卵率
João Pedro Lobão Gomes Castro,Vanessa Neves Guimarães,Patrick de Abreu Barbosa et al.
João Pedro Lobão Gomes Castro et al.
Naproxen is a widely used nonsteroidal anti-inflammatory drug, and previous studies have shown that its administration in mice influenced antral follicle growth and ovulation. Therefore, the present study aimed to investigate the reversibil...
Investigating the impact of psychopharmacological agents on spermatozoa parameters, genomic integrity and chromatin architecture [0.03%]
药理学药物对精子参数、基因组完整性和染色质结构的影响研究
Uğurcan Altiok,Seda Karabulut,Oya Korkmaz et al.
Uğurcan Altiok et al.
This study investigates the effects of psychopharmacological drug on male reproductive health, with a specific focus on sperm parameters, DNA integrity, and chromatin structure. The aim is to understand the potential risks these medications...
Unveiling the role of galectin-3 in patients with azoospermia: potential biomarker for male infertility [0.03%]
人头足糖蛋白(Galectin-3)与男性不育的关系及其作为生物标志物的潜力
Ayse Altun Akpınar,Murat Dursun,Burcin Karamustafaoglu Balcı et al.
Ayse Altun Akpınar et al.
Objective: To investigate the role of the protein galectin-3 (Gal-3) and its effect on fibrosis and apoptosis in testicular tissues of patients with idiopathic non-obstructive azoospermia (iNOA). ...
Effect of in vitro maturation medium supplementation with N-acetylcysteine on the developmental competence of sheep oocytes [0.03%]
N-乙酰半胱氨酸对羊卵母细胞体外成熟培养后发育能力的影响
Sueli de Oliveira Lima,Luana Kealy Pimentel de Oliveira,Isabela Maria Lopes et al.
Sueli de Oliveira Lima et al.
The present study aimed to evaluate the effect of N-acetylcysteine (NAC) on in vitro maturation (IVM) and in vitro embryo production in sheep. Cumulus-oocyte complexes (COCs) were collected and matured in vitro in a control medium or supple...
Ascorbic acid and biotin modulate heat shock protein mRNA expression after thawing in rat sperm [0.03%]
抗坏血酸和生物素调节解冻后大鼠精子热休克蛋白mRNA的表达
Firdevs Yilmaz Dayanc,Oguz Kaan Yalcin,Aysel Eraslan Sakar
Firdevs Yilmaz Dayanc
The successful freezing of rat spermatozoa and the development of innovative cryoprotectant formulations are of great importance in the field of reproductive biotechnology. In the present study, 4 mg/mL Ascorbic acid and 20 nM Biotin were a...