Myosin 7a is required for maintaining the transducing stereocilia and for force transmission to the MET channel during cochlear hair cell development [0.03%]
肌球蛋白7a在耳蜗毛细胞发育期间维持转换立体纤毛并介导力量向MET通道的传递所必需
Anna Underhill,Samuel Webb,Fiorella C Grandi et al.
Anna Underhill et al.
Shaker-1 mice carry a spontaneous missense mutation in Myo7a (Myo7aSh1) that interferes with the motor function of MYO7A. Mutation in the orthologous gene in humans causes syndromic (Usher 1B) or non-syndromic forms of deafness. In hair cel...
Mutations in ammonia transporter RhBG that impair NH3/NH4 + transport in patients with chronic kidney disease [0.03%]
慢性肾脏病患者中损害NH3/NH4+运输的氨转运体RhBG突变
He Zhou,Solange Abdulnour-Nakhoul,L Lee Hamm et al.
He Zhou et al.
Chronic kidney disease (CKD) imposes a substantial health burden globally, with emerging evidence pointing to the significance of metabolic acidosis and low urinary NH4 + excretion resulting in poor CKD outcomes. The present study aims to i...
Modulation of slow and fast oscillations by direct current stimulation in the cerebral cortex in vitro [0.03%]
体外脑皮层直流电刺激对慢波和快波振荡的调制作用研究
Mattia D&#x;Andola,Julia F Weinert,Joana Covelo et al.
Mattia D&#x;Andola et al.
Non-invasive brain stimulation techniques, such as transcranial direct current stimulation, are used in the treatment of neurological disorders. However, the mechanisms by which electric fields modulate cortical network activity are only pa...
Crossing the tipping point: Probing the significance and biological drivers of the mechanobiological shift from tendon adaptation to pathology [0.03%]
探究肌腱适应向病理转变的机悈生物学转换的重要性及生物驱动因素的意义
Nataša Pollak,Denis Korady,Žiga Šink et al.
Nataša Pollak et al.
A maze-like electrical substrate: arrhythmogenic vulnerability in doxorubicin-damaged ventricles [0.03%]
一种迷宫般的电气底物：多柔比星损伤心室的致心律失常易感性
Aimée Obolari Durço,Luiz Fernando Santos Matos,Diego Santos Souza
Aimée Obolari Durço
The pyrogenic mediator prostaglandin E2 elicits warmth seeking via EP3 receptor-expressing parabrachial neurons: a potential mechanism of chills [0.03%]
前列腺素E2通过EP3受体表达的脑桥核神经元诱发寻热行为：发冷的潜在机制
Takaki Yahiro,Yoshiko Nakamura,Kazuhiro Nakamura
Takaki Yahiro
Seeking warmth during infection is a sickness behaviour that contributes to the development of fever and is often accompanied by chills. However, the central mechanism underlying this behaviour remains unknown. We recently reported two asce...
Response to Cheng et al [0.03%]
回应程等人观点
Louise Bradshaw,Alfonso Moreno-Cabañas,Bruno Spellanzon et al.
Louise Bradshaw et al.
A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies [0.03%]
外源物质胎盘转运体表达的研究：从组织和体外实验中获得的经验与教训综述
Rhiannon Pass,Kathryn Wolton,Amanda N Sferruzzi-Perri
Rhiannon Pass
The human placenta acts as a critical barrier within the body, protecting the fetus from the potentially harmful effects of xenobiotics encountered by the mother during pregnancy. Membrane transporter proteins play a central role in this pr...
Five centuries of ductus venosus: The little vessel with a big liver dilemma [0.03%]
五百年来的静脉导管：一个小小的血管面对着巨大的肝脏难题
Torvid Kiserud
Torvid Kiserud
Lennart Bergfeldt
Lennart Bergfeldt