Adaptation or dysfunction? Magnocellular vasopressin neurones' responses to chronic salt-loading [0.03%]
适应性还是功能障碍？巨细胞血管加压素神经元对慢性高盐负荷的反应
Giovanna Arielle de Oliveira,Paula Magalhães Gomes
Giovanna Arielle de Oliveira
An ADP getaway service, not an ATP tank: Insights into the phosphagen system in neurons [0.03%]
ADP逃逸服务，而非ATP坦克：神经元磷酸基因系统的见解
Madeline P Marques,Kartik Venkatachalam
Madeline P Marques
Beyond erythropoietin: What hormonal profiling reveals about the true cost of high-altitude training [0.03%]
超越促红细胞生成素：激素谱分析揭示高原训练的真正代价
Siemon Vermeiren,Nathan Vermaerke,Ruben Robberechts
Siemon Vermeiren
From microstructure to arrhythmia: Structural drivers of re-entrant activity in atrial fibrillation [0.03%]
从微观结构到心律失常：房颤再兴奋活动的结构性驱动因素
Hannah R Cutler
Hannah R Cutler
Compromised synaptic signal from prefrontal cortex to mediodorsal thalamus in Alzheimer's disease models and its rescue by kinase inhibitors [0.03%]
阿尔茨海默病模型中前额叶皮层至中央丘脑信号的损害及激酶抑制剂对其的修复作用
Ping Zhong,Tarek Shaker,Pei Li et al.
Ping Zhong et al.
One of the most important neural circuits controlling cognitive processes is the projection from prefrontal cortex (PFC) to thalamus. To determine the strength of PFC projections to different thalamic nuclei, we performed optogenetic experi...
Metabolic adaptation without microbiome remodelling: Rethinking early host-microbiome dynamics [0.03%]
代谢适应无需微生物组重塑：重新审视宿主-微生物组早期动态过程
Ika N Kadariswantiningsih,Ruthvika Jayanthi,Ekram Arima
Ika N Kadariswantiningsih
A therapeutic trade-off: The paradoxical effects of melatonin treatment on vascular endothelial function in fetal growth-restricted offspring [0.03%]
治疗的权衡：褪黑素治疗对生长受限胎儿后代血管内皮功能矛盾影响的悖论
Charlie Ambrose,Greta Trogen,Sanna Darvish
Charlie Ambrose
Ashley S Meakin
Ashley S Meakin
Dynamic balance of myoplasmic energetics, redox state and protons in a fast-twitch oxidative glycolytic skeletal muscle fibre [0.03%]
快速收缩型氧化糖酵解骨骼肌纤维中肌浆能量、氧化还原状态和质子的动态平衡
Jana Disch,Jeroen A L Jeneson,Daniel A Beard et al.
Jana Disch et al.
To investigate the mechanisms governing energy and redox balance in skeletal muscle, we developed a computational model describing the coupled biochemical reaction network of glycolysis and mitochondrial oxidative phosphorylation (OxPhos) i...
An allostatic load domain-specific metabolic profile in young adults: The African-PREDICT study [0.03%]
非洲-PREDICT研究中的青年成年人特定代谢谱的适应负荷区间问题
Nevah Joubert,Catharina M C Mels,Roan Louw et al.
Nevah Joubert et al.
Allostatic load scores (ALSs) quantify the cumulative physiological burden of sustained stress across neuro-endocrine, metabolic, cardiovascular and inflammatory domains; however ALS is heterogeneous in nature. Using domain-specific urinary...