Robust immune cell infiltration and macrophage senescence occur within a week of recovery after limb immobilization in older adult skeletal muscle [0.03%]
Chad M Skiles,Zachary J Fennel,Paul-Emile Bourrant et al.
Chad M Skiles et al.
Immune cells are critical for modulating inflammation and extracellular matrix remodelling for effective muscle regrowth following disuse atrophy. However, disrupted macrophage function and accumulation of cellular senescence may limit musc...
Reframing gestational diabetes mellitus through two new paradigms: Early detection and lifelong intergenerational follow-up [0.03%]
Marilza Vieira Cunha Rudge,Claudia Garcia Magalhães,Danielle Cristina Honório França et al.
Marilza Vieira Cunha Rudge et al.
Gestational diabetes mellitus (GDM) has traditionally been regarded as a transient metabolic disorder limited to pregnancy, with management directed primarily towards reducing obstetric and perinatal complications. Yet a growing body of evi...
Chintan K Gandhi
Chintan K Gandhi
Incretin-dependent acute and chronic gut responses to fructose exposure in glycaemic control [0.03%]
Paulo Henrique Evangelista-Silva
Paulo Henrique Evangelista-Silva
Jingwu Pan,Peter Hanna,Alan Garfinkel et al.
Jingwu Pan et al.
As a result of the electrotonic effect, under gap junction coupling, a critical number of excited cells is needed to elicit electrical conduction in cardiac tissue, a phenomenon called the source-sink effect. However, it is unclear how epha...
Laura Bear,Callum M Zgierski-Johnston
Laura Bear
Alpha-adrenergic mediated changes in blood pressure variability after hypoxia-ischaemia in preterm fetal sheep [0.03%]
Simerdeep K Dhillon,Michael J Beacom,Victoria J King et al.
Simerdeep K Dhillon et al.
Brain injury in preterm infants is common but often difficult to detect in the early stages. The present study investigated whether evolving preterm brain injury after exposure to hypoxia-ischaemia (HI) is associated with dynamic changes in...
A constitutive modelling framework for applications to in vivo longitudinal data: Evaluation in a 60-day head-down bed rest study on arterial function [0.03%]
Alessandro Giudici,Karen Barchetti,Umit Gencer et al.
Alessandro Giudici et al.
Vascular cells continuously remodel the arterial wall (micro)structure in response to changes in their biomechanical/biochemical environment. Although the functional effects of arterial remodelling can be easily measured, assessing the unde...
What homeostasis leaves out: Kinorhesis, a physiological principle of transformation [0.03%]
稳态所遗漏的：不动目动物的转换生理原则
Nelson D Horseman
Nelson D Horseman
Development of striated muscle microvasculature across the perinatal period in lambs [0.03%]
绵羊围产期条纹肌微血管的发育变化规律研究进展
Eileen I Chang,Saif I Al-Juboori,Tristan B Dear et al.
Eileen I Chang et al.
Transition of the fetus to extrauterine life requires increased cardiac workload and skeletal muscle activity, yet little is known about microvasculature growth during the perinatal period. We collected hindlimb skeletal muscles and cardiac...