On the adaptive significance of group III/IV muscle afferent feedback for the cardiovascular response during sustained locomotion in humans [0.03%]
人类在持续运动中III/IV型肌肉传入反馈对心血管反应的适应意义研究
D Iannetta,F G Laginestra,T S Thurston et al.
D Iannetta et al.
While the cardiovascular consequences of group III/IV muscle afferent feedback have been studied during short-duration exercise, its role during sustained (> 5 min) locomotion remains unknown. Thirteen healthy individuals (4f/9m) completed ...
TMEM16A Ca2+-activated Cl- channel: Functional interactions with cytoskeletal and membrane-associated proteins [0.03%]
胞浆骨架和膜联结蛋白与TMEM16A钙激活氯通道的功能互作研究进展
Hisao Yamamura,Rubii Kondo,Yoshiaki Suzuki et al.
Hisao Yamamura et al.
The calcium-activated chloride (ClCa) channel TMEM16A (also known as ANO1) is widely expressed in epithelial cells, interstitial cells of Cajal, nociceptive neurons and smooth muscle cells, where it plays essential roles in ion transport, n...
Transmural heterogeneity in 3D fibrosis distribution is associated with endo-epicardial electrical dyssynchrony in persistent atrial fibrillation [0.03%]
三维纤维化分布的壁厚度差异与持续性心房颤动的室内外包膜电气异步现象相关
Syed Yusuf Ali,Yazan Mohsen,Shreeram Sabareesan et al.
Syed Yusuf Ali et al.
Despite the established role of endo-epicardial dissociation in the substrate of persistent atrial fibrillation (PsAF), the underlying mechanisms within the 3D atrial wall that lead to this phenomenon are not fully understood. Using persona...
Cardiac regulatory mechanisms: Translating fundamental discoveries into novel therapeutics [0.03%]
心脏调节机制：基础发现向新型药物转化
Tri Q Do,Björn C Knollmann
Tri Q Do
Editorial
The Journal of physiology. 2026 Jul 31. DOI:10.1113/JP291883 2026
Esau Mhandu,Toan Pham,Kenneth Tran et al.
Esau Mhandu et al.
The isolated heart preparation has been the fundamental model for performing mechanical and energetics investigations of cardiac function. Numerous reviews have been conducted detailing the evolution and development of Langendorff-heart and...
Virus-specific alterations in placental structure and transporter expression following maternal arbovirus infection [0.03%]
母体虫媒病毒感染后胎盘结构和转运蛋白表达的病毒特异性改变
Cherley B V Andrade,Enrrico Bloise,Natália L Silva et al.
Cherley B V Andrade et al.
We hypothesized that arboviruses impair the placental expression of key functional markers implicated in fetal brain development. Singleton placentae (n = 54) affected by chikungunya (CHIKV, n = 12), dengue (DENV, n = 8), zika (ZIKV, n = 15...
Unveiling the role of the venous system in arterial hypertension: A computational study [0.03%]
静脉系统在高血压中的作用：一项计算研究
Eleuterio F Toro,Lucas O Müller,Tonja W Emans et al.
Eleuterio F Toro et al.
Arterial hypertension is a prevalent condition and a major risk factor for cardiovascular and neurological diseases. Notably, medical treatment fails to control blood pressure in a large proportion of diagnosed subjects, highlighting gaps i...
Effects of online motor cortex transcranial ultrasound stimulation on interhemispheric inhibition [0.03%]
经颅超声刺激对半球间抑制的影响
Yanqiu Wang,Ke Zeng,Anton Fomenko et al.
Yanqiu Wang et al.
Transcranial ultrasound stimulation (TUS) of the motor cortex (M1) has been found to modulate interhemispheric inhibition (IHI) after sonication (offline effect). However, the effects of M1 TUS on IHI during sonication (online effect) remai...
Electrotactile frequency perception over multiple stimulation sites does not use a winner-takes-all mechanism [0.03%]
多个刺激位点上的电触觉频率感知不采用赢家通吃机制
Alwin So,Hiroyuki Kajimoto,Edward N Crawford et al.
Alwin So et al.
It is not known how the brain extracts vibrotactile stimulus frequency from the peripheral afferent population whose afferents exhibit a wide range of response patterns to a pure frequency stimulus, including afferents which do not respond ...