Extending localized passive heat therapy benefits for individuals with exercise intolerance [0.03%]
延长局部被动热疗对运动不耐受个体的好处
Kevin P Decker,Jacob W Richardson
Kevin P Decker
Hyperthermia-induced changes in blood flow dynamics and their influence on cardiac output [0.03%]
高温引起的血流动力学变化及其对心排血量的影响
Ahmed Ashraf Morgan
Ahmed Ashraf Morgan
Resistance artery vasodilator pathways involved in the antihypertensive effects of cocoa shell extract in rats exposed to fetal undernutrition [0.03%]
与胎儿期营养不良的大鼠降压作用有关的可可壳提取物血管扩张途径
Santiago Ruvira,Pilar Rodríguez-Rodríguez,Fatima Abderrahim et al.
Santiago Ruvira et al.
Fetal undernutrition establishes the foundations for hypertension development, with oxidative stress being a key hallmark. A growing interest in nutraceuticals for treating hypertension and environmental waste concerns prompted the present ...
A simulation study on the role of mitochondria-sarcoplasmic reticulum Ca2+ interaction in cardiomyocyte energetics during exercise [0.03%]
线粒体-肌浆网钙离子相互作用在运动时心肌细胞能量代谢中所发挥作用的仿真研究
Ayako Takeuchi,Satoshi Matsuoka
Ayako Takeuchi
Previous studies demonstrated that the mitochondrial Ca2+ uniporter MCU and the Na+-Ca2+ exchanger NCLX exist in proximity to the sarcoplasmic reticulum (SR) ryanodine receptor RyR and the Ca2+ pump SERCA, respectively, creating a mitochond...
Alessandro Piedimonte,Valeria Volpino,Francesco Campaci et al.
Alessandro Piedimonte et al.
Placebo and nocebo effects modulate symptom perception through expectations and learning processes in various domains. Predominantly, their impact has been investigated on pain and physical performance. However, the influence of placebos an...
Exploring consciousness: Investigating local wakefulness during anaesthesia [0.03%]
探索意识：在麻醉期间局部清醒状态的研究
Dylan F Cooke,Gustavo Balbinot
Dylan F Cooke
William Bechtel,Leonardo Bich
William Bechtel
Since it was inspired by Bernard and developed and named by Cannon, the concept of homeostasis has been invoked by many as the central theoretical framework for physiology. It has also been the target of numerous criticisms that have elicit...
Investigating the effects of artificial baroreflex stimulation on pain perception: A comparative study in no-pain and chronic low back pain individuals [0.03%]
人工血压反射刺激对疼痛感知的影响：无痛和慢性下腰痛患者的比较研究
Alessandra Venezia,Harriet-Fawsitt Jones,David Hohenschurz-Schmidt et al.
Alessandra Venezia et al.
The autonomic nervous system (ANS) and pain exhibit a reciprocal relationship, where acute pain triggers ANS responses, whereas resting ANS activity can influence pain perception. Nociceptive signalling can also be altered by 'top-down' pro...
Comparative Study
The Journal of physiology. 2024 Dec;602(24):6941-6957. DOI:10.1113/JP286375 2024
Intersectin-1 enhances calcium-dependent replenishment of the readily releasable pool of synaptic vesicles during development [0.03%]
intersectin-1通过增强发育过程中的钙依赖性囊泡补充作用来增加可释放囊泡池的大小
Yi-Mei Yang,Adam Fekete,Jason Arsenault et al.
Yi-Mei Yang et al.
Intersectin-1 (Itsn1) is a scaffold protein that plays a key role in coupling exocytosis and endocytosis of synaptic vesicles (SVs). However, it is unclear whether and how Itsn1 regulates these processes to support efficient neurotransmissi...
Chronic late gestation fetal hyperglucagonaemia results in lower insulin secretion, pancreatic mass, islet area and beta- and α-cell proliferation [0.03%]
妊娠晚期慢性胎儿高胰高糖素血症导致胰岛素分泌降低，胰腺质量、胰岛面积和β细胞及α细胞增殖降低
Sarah N Cilvik,Brit Boehmer,Stephanie R Wesolowski et al.
Sarah N Cilvik et al.
Fetal glucagon concentrations are elevated in the presence of a compromised intrauterine environment, as in cases of placental insufficiency and perinatal acidaemia. Our objective was to investigate the impact of late gestation fetal hyperg...