Maturation of spinal motor control through developmental changes in ion currents [0.03%]
离子电流的发育变化与脊髓运动控制的成熟密切相关
Stephanie F Gaudreau,Tuan V Bui
Stephanie F Gaudreau
The maturation of motor control by the nervous system arises from several developmental processes including neurogenesis, the establishment of synaptic connectivity, and the development of neuronal intrinsic properties. The latter, particul...
Changes in interstitial cells of Cajal calcium activity in a diabetic mouse model of delayed gastric emptying [0.03%]
糖尿病胃轻瘫小鼠模型中肠间质细胞钙离子活动的变化特征研究
Elisia Maalouf,Xin-Yi Chai,Jack A Patraw et al.
Elisia Maalouf et al.
Interstitial cells of Cajal (ICC) regulate gastrointestinal motility by generating electrical slow waves that orchestrate downstream calcium (Ca2 +) waves and coordinate smooth muscle contractions. A reduced ICC number has been reported in ...
Functional role of Nav1.8 channels in action potentials of mouse CGRP-lineage dorsal root ganglion neurons [0.03%]
小鼠CGRP谱系DRG神经元中Nav1.8通道在动作电位中的功能作用
Tomás Osorno,Robert G Stewart,Akie Fujita et al.
Tomás Osorno et al.
Primary sensory neurons that sense noxious stimuli (nociceptors) are unusual in possessing two major components of voltage-dependent sodium channel current with different voltage dependence and kinetics. We used pharmacology to characterize...
Challenging conventional wisdom: A fresh look at the litter effect in rats [0.03%]
挑战传统观点：对大鼠环境丰富化研究中杂物效应的新思考
Adrianne G Huxtable,Emily G Flanigan,Michael L Frazure et al.
Adrianne G Huxtable et al.
This retrospective study challenges the assumption that physiological variance among neonates is greater between litters than within litters of multiparous species like rats. Conventional wisdom holds that litters - not individual pups - sh...
Who pays for participation? Hidden personal costs in (exercise) physiology [0.03%]
谁来承担参与的成本？生理学中被隐藏的个人成本（关于锻炼）
Arthur Henrique Bossi
Arthur Henrique Bossi
Multiscale mechanistic modelling of heterogeneity in cardiac sub-cellular calcium handling accounting for variable t-system density [0.03%]
变t系统密度的心肌细胞内钙异质性多尺度机制模型
Michael A Colman,Yohannes Shiferaw,David Conesa
Michael A Colman
Spatial properties of subcellular calcium handling in cardiac myocytes underpin both normal and abnormal functions. The structure and density of the transverse and axial tubular system (t-system) strongly determine the spatiotemporal synchr...
The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention-deficit/hyperactivity disorder [0.03%]
孕前压力对神经发育的影响：自闭症谱系障碍和注意力缺陷多动障碍的启示
Samaneh Ahmadian-Moghadam,Ehsan Saboory,Shiva Roshan-Milani
Samaneh Ahmadian-Moghadam
Emerging evidence indicates that stress experienced by parents before conception can influence offspring neurodevelopment through enduring neuroendocrine and epigenetic mechanisms. This review addresses the central question of how pregestat...
Influence of sex and heart size on cardiovascular adaptations to 2 years of endurance exercise training in sedentary middle-aged adults [0.03%]
性别和心脏大小对久坐不动的中年成人两年耐力运动训练心血管适应的影响
Eric T Hedge,Erin J Howden,Justin S Lawley et al.
Eric T Hedge et al.
Sedentary ageing is linked to low cardiorespiratory fitness and the development of a small, stiff heart - risk factors for heart failure. Endurance exercise training reverses the effects of sedentary ageing on the heart when started in midd...