Ketosis enhances vascular function, angiogenic signalling and the erythropoietic response to exercise and hypoxia [0.03%]
酮症增强血管功能，促血管生成信号以及运动和缺氧下的红细胞生成反应
Myrthe Stalmans,Benjamin Narang,Nathan Vermaerke et al.
Myrthe Stalmans et al.
Regular physical activity improves vascular function and promotes angiogenesis and erythropoiesis, which are further augmented by hypoxia. Early evidence suggests that long-term exogenous ketosis (EK) can enhance vascular function and angio...
The endogenous cannabinoid system gates plasticity of tonic GABA inhibition [0.03%]
内源性大麻素系统调控基线GABA抑制的可塑性
Roberto Colangeli,Fiorenzo Conti
Roberto Colangeli
GABAergic neurotransmission generates two types of inhibition: a phasic inhibition, determined by the transient activation of synaptic GABAA receptors, that elicits inhibitory postsynaptic currents, and a tonic inhibition caused by persiste...
Jake P Muma,Kylee S West,Sofia O Sanchez
Jake P Muma
Richard J A Wilson,Fiona McDonald
Richard J A Wilson
Artificial gravity during prolonged bed rest preserves resting metabolic rate but not muscle function: Evidence from the BRACE study [0.03%]
长期卧床期间使用人工重力可保持静息代谢率但不能保持肌肉功能：BRACE研究的证据
Saul Martin-Rodriguez,Mirko Mandić,Claire Laurens et al.
Saul Martin-Rodriguez et al.
Prolonged head-down tilt bed rest induces metabolic and neuromuscular deconditioning. This study examined whether supine cycling exercise, with/without artificial gravity (AG), preserves resting metabolic rate (RMR) during 60 days of bed re...
In vivo quantification of mitochondrial O2 affinity in human skeletal muscle using 1H-magnetic resonance spectroscopy of deoxy-myoglobin [0.03%]
利用脱氧肌红蛋白的氢磁共振光谱法对人骨骼肌线粒体氧气亲和力进行量化研究
Muhammet Enes Erol,Alexs A Matias,Corinna F Serviente et al.
Muhammet Enes Erol et al.
Mitochondrial oxygen (O2) affinity is a fundamental determinant of oxidative phosphorylation capacity, which has yet to be directly measured in human skeletal muscle in vivo. To determine the apparent mitochondrial O2 affinity (i.e. P50) of...
Elisabetta Cerbai
Elisabetta Cerbai
NMDA and glycine receptors provide dual presynaptic regulation on climbing fibre inputs to cerebellar Purkinje cells [0.03%]
NMDA和甘氨酸受体共同调节小脑浦肯野细胞的爬行纤维输入
David C H Benton,Alan D Robertson,Matthew Caldwell et al.
David C H Benton et al.
Presynaptic receptors are important regulators of CNS activity. We have examined presynaptic receptor populations using a vibrodissociated rat cerebellar Purkinje cell preparation. In this preparation, NMDA receptor immunoreactivity co-loca...
Uwe Proske,Bernhard M Weber
Uwe Proske
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells [0.03%]
糖皮质激素调节人胎脑内皮细胞的药物转运功能
Nikola Ivanovski,Phetcharawan Lye,Enrrico Bloise et al.
Nikola Ivanovski et al.
Synthetic glucocorticoid (sGC) may be administered to women throughout gestation. Animal studies have shown that sGC can modulate the function of key blood-brain barrier (BBB) drug transporters P-glycoprotein (P-gp; encoded by ABCB1) and br...