Effect of tranexamic acid for acute spontaneous intracerebral haemorrhage: a systematic review and individual patient data meta-analysis [0.03%]
氨甲环酸治疗急性自发性脑出血的疗效：系统评价和个体患者数据分析
Chaamanti Sivakumar Menon,Zhe Kang Law,Lisa Jane Woodhouse et al.
Chaamanti Sivakumar Menon et al.
Background: Spontaneous intracerebral haemorrhage (ICH) has high rates of mortality with no proven haemostatic treatment. We conducted the first systematic review and individual patient data meta-analysis (IPDMA) to asses...
Pathogenic properties of myasthenia gravis AChR autoantibodies associate with clinical response to efgartigimod [0.03%]
重症肌无力AChR自身抗体的致病性与Efgartigimod临床疗效的关系
Fatemeh Khani-Habibabadi,Fien M Verhamme,Mahan Moshir et al.
Fatemeh Khani-Habibabadi et al.
Background: Efgartigimod, a neonatal Fc receptor (FcRn) blocker, effectively reduces total IgG, including pathogenic acetylcholine receptor (AChR) autoantibodies in myasthenia gravis (MG); however, clinical responses vary...
Diagnostic performance of machine learning models versus established risk stratification for intracranial aneurysm rupture: a systematic review and bivariate meta-analysis [0.03%]
机器学习模型与颅内动脉瘤破裂现有风险分层诊断性能的系统评价和双元meta分析
Shaan Patel,Shiva A Nischal,Yi-Hein Chai et al.
Shaan Patel et al.
Background: Machine learning (ML) models have been proposed to improve the discrimination of intracranial aneurysm rupture status beyond established clinical risk stratification tools. However, reported performance is het...
Finite depletion, sustained control: can impulse therapy prevent rebound activity in multiple sclerosis? [0.03%]
有限的耗竭与持续控制：脉冲疗法能否防止多发性硬化症复发？
Marc Pawlitzki,Lars Masanneck,Antonio Scalfari et al.
Marc Pawlitzki et al.
Long-term prediction of traumatic brain injury outcome using the CBI-M framework [0.03%]
基于CBI-M框架的创伤性脑损伤长期预后预测模型研究
Gershon Spitz,Marina Downing,Megan Carty et al.
Gershon Spitz et al.
Background: Long-term functional and vocational outcomes after traumatic brain injury (TBI) remain difficult to predict, limiting prognostic counselling and rehabilitation planning. We aimed to evaluate the Clinical-Bioma...
Discrepancies between patient-reported and physician-reported severity and disability in functional and non-functional movement disorders [0.03%]
功能和非功能性运动障碍患者的病情严重程度及残疾程度与医生报告结果的差异性分析
Olof Cb Vermeulen,Tjerk J Lagrand,Jeannette Gelauff et al.
Olof Cb Vermeulen et al.
Background: Functional movement disorder (FMD) is a common cause of debilitating symptoms in neurology patients. Due to the stigma that is associated with FMD, it is possible that discrepancies between patient and physici...
Pre-existing mental health disorders are associated with an increased risk of traumatic brain injury [0.03%]
术前精神健康障碍与创伤性脑损伤的风险增加有关
Allie L Heineman,Roman Jandarov,Andrew M Ferguson et al.
Allie L Heineman et al.
Background: Traumatic brain injury (TBI) is a major public health concern with significant morbidity and mortality. Mental health disorders (MHDs) are known to arise after TBI. Conversely, we assessed the relationship bet...
Comparative effectiveness of ocrelizumab in subgroups of patients with multiple sclerosis: a multi-registry observational cohort study [0.03%]
奥齐珠单抗治疗多发性硬化症不同亚型患者的疗效比较：多登记处观察队列研究
Izanne Roos,Sifat Sharmin,Dana Horakova et al.
Izanne Roos et al.
Background: Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, is a high-efficacy therapy for multiple sclerosis (MS). Methods: ...
Acquired vitamin B6 deficiency in POEMS: a marker of disease activity and cause of neuropathy? [0.03%]
POEMS综合征继发性维生素B6缺乏：疾病活动的标志和周围神经病变的原因吗？
Oliver Tomkins,Simon Alexander Samuel Pope,Youssef Khalil et al.
Oliver Tomkins et al.
Background: POEMS syndrome is a rare, life-threatening multisystem disease driven by clonal plasma cell proliferation and characterised by disabling neuropathy, a monoclonal plasma cell disorder and diagnostic paraneoplas...