Metabolic brain networks in dementia with Lewy bodies: from prodromal to manifest disease stages [0.03%]
路易体痴呆代谢脑网络：从前驱期到显形期变化规律研究
Matej Perovnik,Urban Simončič,Jan Jamšek et al.
Matej Perovnik et al.
Background: Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia, yet it remains under-recognised and misdiagnosed, which delays treatment, causes inaccurate prognosis and limits research o...
Atsuhiro Higashi,Yasuaki Mizutani,Reiko Ohdake et al.
Atsuhiro Higashi et al.
Background: Weight loss is a substantial non-motor feature of Parkinson's disease (PD) associated with worse clinical outcomes, but the underlying mechanisms remain poorly understood. Thus, we investigated the mechanisms ...
Vitamin D intake and multiple sclerosis risk in the Norwegian Mother, Father and Child cohort [0.03%]
挪威人口队列中维生素D摄入与多发性硬化风险的关系
Akash Kapali,Anne Kjersti Daltveit,Kjell-Morten Myhr et al.
Akash Kapali et al.
Background: Higher vitamin D has consistently been associated with a lower multiple sclerosis (MS) risk, but some controversy remains about whether this is due to vitamin D itself or sunlight. ...
Intrathecal Epstein-Barr virus reactivation in patients with autoimmune glial fibrillary acidic protein astrocytopathy [0.03%]
自身免疫性胶质纤维酸性蛋白天疱疮患者的脑脊液EB病毒再活化
Hideo Handa,Akiyuki Uzawa,Akio Kimura et al.
Hideo Handa et al.
Background: The pathogenic mechanisms underlying autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy (GFAP-A), a central nervous system disorder associated with GFAP autoimmunity, remain controversial. The pr...
Epstein-Barr virus reactivation as a trigger in autoimmune GFAP astrocytopathy [0.03%]
EB病毒再激活作为自身免疫GFAP星形胶质细胞病的诱因
Shannon A Bernard Healey,Laura Benjamin
Shannon A Bernard Healey
Swedish nationwide study of 377 patents with non-aneurysmal subarachnoid haemorrhage: a disease with distinct demographics and risk factors [0.03%]
瑞典全国非动脉瘤性蛛网膜下腔出血的多中心研究：一种具有独特的流行病学特征及危险因素的疾病
Paula Klurfan,Asgeir Jakola,Bryndís Baldvinsdóttir et al.
Paula Klurfan et al.
Background: Non-aneurysmal subarachnoid haemorrhage (NASAH) accounts for less than 20% of spontaneous subarachnoid haemorrhage (SAH). However, its epidemiological characteristics, risk factors and aetiology remain poorly ...
Kasper Katisko,Mikko Aaltonen,Kalle Aho et al.
Kasper Katisko et al.
Background: The socioeconomic burden of early onset dementia (EOD) defined as disease onset before the age of 65 years, is substantial due to its widespread disabling effects in relatively young individuals. While dementi...
Moderate-high efficacy disease-modifying therapies reduce relapse risk in late-onset multiple sclerosis [0.03%]
中等至高度有效的疾病修正治疗可降低晚期发病多发性硬化症的复发风险
Yi Chao Foong,Daniel Merlo,Melissa Gresle et al.
Yi Chao Foong et al.
Introduction: Late-onset multiple sclerosis (LOMS) now comprises over 10% of MS diagnoses in contemporary cohorts. The effectiveness of disease-modifying therapies (DMTs) in LOMS is unclear. We aimed to establish the comp...
Trajectories of Glasgow Outcome Scale-Extended after traumatic brain injury: an analysis of the TRACK-TBI cohort [0.03%]
TRACK-TBI队列患者创伤性脑损伤后的Glasgow预后量表评分变化规律分析
Peter Paramaseeven Curpen,Xuan Vinh To,Ming Lu et al.
Peter Paramaseeven Curpen et al.
Background: Recovery following traumatic brain injury (TBI) is highly heterogeneous. Characterising longitudinal functional trajectories may enable more individualised care and inform the trial design. This study aimed to...
Going beyond seizure control: evidence for cost-effectiveness of epilepsy surgery [0.03%]
超越癫痫控制：癫痫手术成本效益的证据
Gagandeep Singh
Gagandeep Singh