Adherence to the MIND diet and longitudinal brain structural changes over a decade: evidence from the Framingham heart study offspring cohort [0.03%]
Hui Chen,Gulisiya Hailili,Lu-Sha Tong et al.
Hui Chen et al.
Background: The MIND diet was favourably linked to lower risk of neurodegenerative diseases. While previous cross-sectional studies implied its beneficial associations with brain imaging markers, its associations with lon...
Functional and effective connectivity disruptions of the dopaminergic reward circuit in multiple sclerosis patients with depression [0.03%]
Giada Lombardi,Elisa Leveraro,Emilio Cipriano et al.
Giada Lombardi et al.
Background: Despite the impact of depression in multiple sclerosis (MS), the neurobiological mechanisms underlying its pathogenesis are still poorly understood. Disrupted functional connectivity (FC) within the reward cir...
Clinically reported covert cerebrovascular disease and risk of neurological disease: a whole-population cohort of 367 988 people using natural language processing [0.03%]
Matthew Henry Iveson,Mome Mukherjee,Emma M Davidson et al.
Matthew Henry Iveson et al.
Background: The relevance of covert cerebrovascular disease (CCD) in practice is uncertain, partly because estimation of risk in whole clinical populations is difficult. Studies have had success extracting CCD from clinic...
Sex-related and age-related differences in healthcare use before multiple sclerosis symptom onset: a matched cohort study [0.03%]
Marta Ruiz-Algueró,Feng Zhu,Farahnaz Amini et al.
Marta Ruiz-Algueró et al.
Background: Increased healthcare use precedes classical multiple sclerosis (MS) symptom onset. Limited evidence exists on sex and age variation. We assessed physician visit patterns pre-MS onset by sex and age. ...
Echocardiographic wall motion abnormalities in patients with stroke may warrant cardiac evaluation [0.03%]
卒中患者超声心动图异常可能需要心脏评估
Shadi Yaghi,Andrew D Chang,Brittany A Ricci et al.
Shadi Yaghi et al.
Background: The aetiology of wall motion abnormalities (WMA) in patients with ischaemic stroke is unclear. We hypothesised that WMAs on transthoracic echocardiography (TTE) in the setting of ischaemic stroke mostly reflec...
Risk of neurodevelopmental disorders associated with paternal use of valproate during spermatogenesis [0.03%]
父亲在精子发生期间使用丙戊酸与神经发育障碍的相关风险
Neda Razaz,Jonas Soderling,Torbjörn Tomson et al.
Neda Razaz et al.
Background: Regulatory authorities have raised concerns about potential teratogenic and neurodevelopmental disorders (NDDs) risks associated with paternal valproate use during spermatogenesis, leading to restrictions. We ...
Patients with symmetric Parkinson's disease do poorly with subthalamic stimulation [0.03%]
皮质下刺激治疗对称性帕金森病患者的疗效不佳
Stefanie Theresa Jost,Camilla Atwani,Philipp Alexander Loehrer et al.
Stefanie Theresa Jost et al.
Background: Motor asymmetry is a hallmark of Parkinson's disease (PD), but ~20% of patients present with symmetric motor signs, which are associated with faster disease progression and poorer dopaminergic response. The im...
Physical activity decreases the likelihood of peripheral neuropathy in persons with diabetes [0.03%]
运动可降低糖尿病患者发生外周神经病变的风险
Evan L Reynolds,David Russman,Georgios Baskozos et al.
Evan L Reynolds et al.
Background: Clinical guidelines recommend physical activity (PA) to prevent diabetic peripheral neuropathy (DPN). However, these recommendations lack specificity in terms of optimal PA intensity and duration. We aimed to ...
Is it time for the removal of valproate restrictions in men? Further evidence from a new study [0.03%]
去掉男性使用丙戊酸钠的禁忌？一项新研究提供了更多证据
Heather Angus-Leppan
Heather Angus-Leppan
Clinical and laboratory features of juvenile-onset anti-NF155 autoimmune nodopathy [0.03%]
抗NF155自身免疫性节结病的临床和实验室特征
Xinmei Wen,Li Di,Wenjia Zhu et al.
Xinmei Wen et al.
Background: Neurofascin 155 autoimmune nodopathy (NF155 AN) is a recently recognised immune-mediated neuropathy distinct from chronic inflammatory demyelinating polyneuropathy. While adult-onset cases have been increasing...