Telomere length as a marker of biological age in paediatric multiple sclerosis [0.03%]
端粒长度在儿科多发性硬化症中的生物学衰老标志物作用
Kayla Jacques,Jonathan Race,Christopher Goyne et al.
Kayla Jacques et al.
Background: Increased chronological age correlates with reduced relapse rates and increased disability in multiple sclerosis (MS). Biological age may better capture ageing's impact on MS and might accelerate due to MS its...
Kinematic analysis reliably assesses GPi-DBS effectiveness in dystonia [0.03%]
动力学分析可靠地评估了丘脑底核深部电刺激治疗肌张力障碍的效果
Edouard Courtin,Juliette Thomas,Etienne Guillaud et al.
Edouard Courtin et al.
Background: Severe forms of generalised (GD) or cervical dystonia (CD) can be effectively treated with deep brain stimulation (DBS) of the globus pallidus interna (GPi). However, objectively assessing DBS effectiveness re...
Xiaojing Peng,Mario H Flores-Torres,Marianna Cortese et al.
Xiaojing Peng et al.
Background: Estimators of biological age, such as epigenetic clocks, are promising biomarkers for neurological disorders where the risk significantly increases with age, such as Parkinson's disease (PD). The purpose of th...
Risk of amyloid-related imaging abnormalities associated with anticoagulant therapy in patients with Alzheimer's disease treated with anti-amyloid monoclonal antibodies: a systematic review and meta-analysis [0.03%]
抗凝治疗对阿尔茨海默病患者单克隆抗体治疗的淀粉样蛋白相关影像学异常风险的影响：系统评价和-meta分析
Eckhard Schlemm,Serge Gauthier,Tim Magnus et al.
Eckhard Schlemm et al.
Deep brain stimulation for epilepsy: optimal targeting and clinical outcomes [0.03%]
用于治疗癫痫的深部脑刺激：最佳靶点和临床疗效
Lauren A Hart,Aaron E L Warren,Niels Pacheco-Barrios et al.
Lauren A Hart et al.
Background: Deep brain stimulation (DBS) has been investigated for patients with drug-resistant epilepsy who are not candidates for resective surgery. Because different types of epilepsy involve distinct brain networks, n...
Impact of flat-panel detector CT distal occlusion tracker (DOT) sign on early neurological deterioration after endovascular thrombectomy [0.03%]
基于CT探测器远端阻塞征(DOT)的急性缺血性卒中患者血管内治疗后早期神经功能恶化的预测价值
Valentina Tudisco,Michele Romoli,Francesca Giannini et al.
Valentina Tudisco et al.
Background: A relevant proportion of patients experience early neurological deterioration (END) despite technically successful recanalisation for acute ischaemic stroke. We prospectively assessed the distal occlusion trac...
Role of ambulatory blood pressure monitoring as a non-invasive autonomic screening tool in hereditary transthyretin amyloidosis [0.03%]
动态血压监测在遗传性转甲状腺素蛋白淀粉样变自主神经筛查中的作用
Laura Sander,Giacomo Chiaro,Domenico Abelardo et al.
Laura Sander et al.
Background: Hereditary transthyretin amyloidosis (ATTRv) is a life-threatening disease with frequent autonomic manifestations. Autonomic testing is not widely accessible, which might cause underdiagnosis of autonomic dysf...
Catherine J Mummery,Jill Rasmussen,Dan Blackburn et al.
Catherine J Mummery et al.
Lecanemab is an anti-amyloid monoclonal antibody, recently approved in the UK as a treatment for mild cognitive impairment (MCI) and mild dementia due to Alzheimer's disease (AD) in adults who are apolipoprotein E ε4 gene (APOE4) heterozyg...
Appropriate use recommendations in search of reimbursement: lecanemab and the UK dilemma [0.03%]
适当使用报销推荐：lecanemab与英国的困境
Antonio Ancidoni
Antonio Ancidoni
Epilepsy-related premature mortality in adults with intellectual disability in England: a population-based analysis [0.03%]
英格兰智力残疾成年人的癫痫相关过早死亡：基于人口的分析
Rohit Shankar,William E Henley,Sharlene Allaudin et al.
Rohit Shankar et al.
Background: Epilepsy affects 22.2% of people with intellectual disability compared with 1% of the general population. This study aims to identify characteristics associated with epilepsy-caused deaths in adults with intel...