Vascular cognitive impairment and dementia in old age: cognition and beyond [0.03%]
血管性认知功能障碍和痴呆：老年人的认知及其他方面
Ana Charlotte Menart,Lisanne Tap,Frank J Wolters et al.
Ana Charlotte Menart et al.
Vascular cognitive impairment and dementia (VCID) is common in the ageing population. VCID is often the cause of alterations in vascular perfusion or function, reflected for example in strokes, haemorrhages, and small vessel disease. The ri...
Tailored implementation of national recommendations on falls prevention amongst older adults in municipalities in Norway-FALLPREVENT-a hybrid type 3 cluster-randomised trial [0.03%]
针对挪威老年人防跌倒的国家级建议的地方化实施——Fallprevent混合型3类群组随机对照试验
Maria Bjerk,Are Hugo Pripp,Katrine Damgaard Skyrud et al.
Maria Bjerk et al.
Background: Implementation of evidence-based falls prevention recommendations within community health care settings is variable and suboptimal. Objective:...
Randomized Controlled Trial
Age and ageing. 2025 Aug 29;54(10):afaf312. DOI:10.1093/ageing/afaf312 2025
Life-course leisure-time physical activity benefits cognitive health through decelerating epigenetic ageing acceleration: results from a large prospective cohort study [0.03%]
一项大型前瞻性队列研究结果表明生命历程中的闲暇时间体力活动通过减缓表观遗传衰老加速造福认知健康
Ziyang Ren,Lirong Nie,Yuchun Sun et al.
Ziyang Ren et al.
Background: Leisure-time physical activity (LTPA) in mid-to-old life is recommended for cognitive management, but evidence linking life-course LTPA to cognitive health remains underexplored. ...
Diagnostic utility of speech-based biomarkers in mild cognitive impairment: a systematic review and meta-analysis [0.03%]
轻度认知障碍中基于语音的生物标志物诊断效用的系统评价和meta分析
Zahra Jafari,Melissa K Andrew,Kenneth J Rockwood
Zahra Jafari
Background: Among various tools developed for mild cognitive impairment (MCI) detection, analysing speech features is a non-invasive and cost-effective approach that shows promise for early detection. This review aimed to...
Meta-Analysis
Age and ageing. 2025 Aug 29;54(10):afaf316. DOI:10.1093/ageing/afaf316 2025
Overactive bladder medications and risk of emergency hospital admissions with delirium in adults without dementia: self-controlled case series [0.03%]
抗过度活跃膀胱药物与成年人不明痴呆急诊住院风险的关系：同一患者自我对照研究
Kathryn Richardson,Irene Petersen,Katharina Mattishent et al.
Kathryn Richardson et al.
Aims: We examined whether anticholinergic overactive bladder (OAB) medications are associated with emergency hospital admissions with delirium in adults without dementia. ...
Implementation of blood flow restriction training in the acute geriatric unit [0.03%]
急性老年病区血液限制训练的实施
Raoul De Smet,Astrid D H Brys,Patrick Calders et al.
Raoul De Smet et al.
Background: Hospital-associated physical decline is common among older adults. High-load training mitigates this but, is often impractical in acute care settings. Blood flow restriction (BFR) training is a promising low-l...
Observational Study
Age and ageing. 2025 Aug 29;54(10):afaf315. DOI:10.1093/ageing/afaf315 2025
Reduction of adverse clinical outcomes among older patients within a structured primary care programme: findings from a 12-year cohort study in Germany (2010-22) [0.03%]
德国一项为期12年的队列研究结果：在结构化的初级保健计划中减少老年人不良临床结局（2010-2022年）
Kateryna Karimova,Catriona Friedmacher,Dorothe Lemke et al.
Kateryna Karimova et al.
Background: Previous studies have shown that structured and coordinated primary care may reduce adverse outcomes for older patients. However, little is known about the long-term effects of these programmes. In 2004, Germa...
Observational Study
Age and ageing. 2025 Aug 29;54(10):afaf310. DOI:10.1093/ageing/afaf310 2025
Campbell and Cochrane evidence on promoting cognitive capacity across life course: a mapping review [0.03%]
坎贝尔与科克霍恩关于毕生促进认知储备的证据：系统评价映射研究
Vivian A Welch,Monserrat Conde,Victoria I Barbeau et al.
Vivian A Welch et al.
Background: Cognitive capacity and function affect daily activities, independence, and overall well-being across the life course. Objective: ...
Does the frailty index applied to randomised controlled trials really measure frailty? [0.03%]
应用于随机对照试验的脆弱性指数真的能衡量脆弱性吗？
Rîme Bousetta,David A McAllister,Heather Wightman et al.
Rîme Bousetta et al.
Background: Cumulative deficit frailty indices from randomised controlled trials (RCT) are increasingly used to assess whether trial findings are applicable to people living with frailty. The aim of this paper was to exam...
Older adult risk classification for anticholinergics (ORCA): a Delphi panel-validated scale [0.03%]
成人抗胆碱药风险分类（ORCA）评分：德尔菲专家组验证的量表
Ine Simal,Annemie Somers,Jesper Ryg et al.
Ine Simal et al.
Background: Drugs with anticholinergic properties (DAP) are widely prescribed in older adults for various medical conditions. However, their cumulative anticholinergic burden is associated with adverse outcomes, including...