Exploring the impact of treatments (pharmacological and nonpharmacological) on independence and wellbeing in people with Parkinson's and their carers-a qualitative synthesis [0.03%]
探索治疗（药理和非药理）对帕金森病患者及其照顾者独立性和幸福感影响的定性综合分析
Cameron Wilson,Megan Hanrahan,Katie Brittain et al.
Cameron Wilson et al.
Background: The loss of mobility and independence is a significant marker in the progression of neurodegenerative conditions such as Parkinson's disease (PD). As existing reviews have focused on the objective impact of PD...
Association of neuroticism with incident dementia and cognitive function: 26-year follow-up of EPIC-Norfolk study [0.03%]
神经质与发病性痴呆和认知功能的关系：EPIC-Norfolk研究26年随访结果
Yaqing Gao,Robert N Luben,Shabina Hayat et al.
Yaqing Gao et al.
Background: Neuroticism is a stable personality trait associated with increased vulnerability to mental and physical disorders. This study examined whether neuroticism is associated with the risk of dementia, particularly...
There is more than one Frailty Index, and some may not be fit for purpose [0.03%]
不止一种脆弱性指数，有些可能不适合使用
Lucy Pollock
Lucy Pollock
Nathalie van der Velde
Nathalie van der Velde
Association between vaccinations and risk of dementia: a systematic review and meta-analysis [0.03%]
关于疫苗接种与痴呆风险之间关系的系统评价和meta分析
Stefania Maggi,Tamàs Fulöp,Elda De Vita et al.
Stefania Maggi et al.
Importance: Dementia is a highly prevalent issue in older people. Whilst the prevention of dementia is a public health priority, the role of vaccinations is still largely unexplored. ...
Meta-Analysis
Age and ageing. 2025 Oct 30;54(11):afaf331. DOI:10.1093/ageing/afaf331 2025
Johannes Aemilius Griese,Luca Ünlü,James van Oppen et al.
Johannes Aemilius Griese et al.
Background: Older emergency patients have complex health needs and diverse personal priorities not captured by traditional single-disease approaches. Asking 'what matters most' may facilitate a more patient-centred approa...
Observational Study
Age and ageing. 2025 Oct 30;54(11):afaf334. DOI:10.1093/ageing/afaf334 2025
Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials [0.03%]
褪黑素对认知障碍老年人睡眠和认知结果的影响：随机对照试验的系统综述和荟萃分析
Nosipho Treasure Mdluli,Kondwani Joseph Banda,Yun-Chen Chang
Nosipho Treasure Mdluli
Objectives: To quantify the effects of melatonin on total sleep time and global cognition, and to examine secondary outcomes (sleep efficiency, circadian markers, neuropsychiatric symptoms, depression, activities of daily...
Meta-Analysis
Age and ageing. 2025 Oct 30;54(11):afaf333. DOI:10.1093/ageing/afaf333 2025
Prediction of postoperative delirium in older adults from preoperative cognition and occipital alpha power from resting-state electroencephalogram [0.03%]
基于术前认知和静息态脑电图枕区alpha节律功率预测老年人术后谵妄风险
Matthew H Ning,Andrei Rodionov,Jessica M Ross et al.
Matthew H Ning et al.
Background: Postoperative delirium is the most common complication following surgery amongst older adults, and has been consistently associated with increased mortality and morbidity, cognitive decline, loss of independen...
Observational Study
Age and ageing. 2025 Oct 30;54(11):afaf330. DOI:10.1093/ageing/afaf330 2025
Residual atherosclerotic risk in older patients with atherosclerotic cardiovascular disease: where inflammation meets lipoprotein(a) [0.03%]
动脉粥样硬化性心血管病患者合并高脂蛋白(a)血症的残余动脉粥样硬化风险：炎症与脂蛋白(a)相遇的地方
Xiaohui Bian,Hao-Yu Wang,Yuanlin Guo et al.
Xiaohui Bian et al.
Background: Inflammation and hyperlipidaemia contribute with similar magnitude to the risk of future atherothrombotic events. However, the relative importance of high-sensitivity CRP (hsCRP) and lipoprotein(a) (Lp[a]) as ...
Late-life depression in sub-Saharan Africa: a stratified meta-analysis of prevalence by diagnostic method and study setting [0.03%]
撒哈拉以南非洲地区晚期抑郁的分层元分析：诊断方法和研究设置下的患病率
Nosipho Treasure Mdluli,Kondwani Joseph Banda,Yun-Chen Chang
Nosipho Treasure Mdluli
Background: Depression among older adults in Sub-Saharan Africa (SSA) is an increasing public health concern. This is the first meta-analysis to report stratified prevalence estimates based on assessment method (diagnosti...