Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium [0.03%]
抗菌治疗在坏死性软组织感染中的应用:大巴黎SURFAST联盟的叙述性综述
Caroline Charlier,Bérénice Souhail,Stéphane Dauger et al.
Caroline Charlier et al.
Necrotizing soft tissue infections (NSTIs) are uncommon, yet rapidly progressive and potentially fatal conditions. However, evidence-based guidance on antibiotic therapy remains limited. Current recommendations emphasize the need for broad-...
Tailored strategy for managing post-cardiac-arrest patients using an early stratification tool: a French university hospital experience [0.03%]
基于早期分层工具管理心脏骤停后患者策略的研究:法国大学医院的经验报告
Clotilde Bachollet,Alain Cariou,Hélène Caillon et al.
Clotilde Bachollet et al.
Rethinking PbtO₂ responses to hyperoxemia: laying the groundwork for a new approach to multimodal neuromonitoring [0.03%]
重新思考PbtO₂对高氧血症的反应:多模态神经监测新方法的基础研究
Gurgen Harutyunyan Hovhanisyan,Garnik Harutyunyan Jaghatspanyan,Suren Soghomonyan
Gurgen Harutyunyan Hovhanisyan
The interpretation of brain tissue oxygen tension (PbtO₂) in neurocritical care remains controversial, particularly during hyperoxemic conditions. In this comment on the article by Bögli et al., we propose that the observed rise in PbtO₂...
Reconsidering the urea-to-creatinine ratio as a signal of muscle catabolism in patients with cirrhosis [0.03%]
重新考虑尿素与血清肌酐比值在肝硬化患者肌肉分解信号中的作用
Abderrahim Oussalah,Vincent Haghnejad,Alexia Audouy et al.
Abderrahim Oussalah et al.
ApoA1/HDL and sepsis-associated vascular endothelial injury: a narrative review [0.03%]
载脂蛋白A-I/高密度脂蛋白与脓毒症血管内皮损伤:叙述性综述
Kailin Guo,Chang Hu,Le Li et al.
Kailin Guo et al.
Sepsis remains a leading cause of global mortality, primarily driven by microvascular collapse stemming from severe vascular endothelial injury. Within this pathology, the dramatic depletion of Apolipoprotein A1 (ApoA1) and its carrier, hig...
Distinct pathogen spectrum in immunocompromised patients with severe pneumonia [0.03%]
免疫抑制患者中严重肺炎的病原体分布特点
Wenxiao Zhang,Lingtong Huang,Huanzhang Shao
Wenxiao Zhang
Discovery of a resistant cohort to acute kidney injury: insights from patients with septic shock [0.03%]
急性肾损伤抗性患者的发现:来自脓毒性休克患者的研究启示
Dana Y Fuhrman,Towia A Libermann,Neil A Hukriede et al.
Dana Y Fuhrman et al.
Background: Acute kidney injury (AKI) is a significant complication among critically ill patients, particularly those with sepsis, yet no specific therapies exist. Progress in some diseases has been achieved by analyzing ...
Fadi Khalaf,Daniella Touma,Sean Saldanha et al.
Fadi Khalaf et al.
Burn injuries are complex and devastating traumas that trigger a profound systemic metabolic response, characterized by hyperglycemia, insulin resistance, and a hypermetabolic state. Notably, hyperglycemia is a critical determinant of worse...
Potential therapeutic benefit of exogenous ketone ester administration in delirium: a narrative review [0.03%]
酮酯应用于谵妄治疗的潜在益处:综述性论述论文
Ryan Smith,Fiona Harrison,Julie Bastarache et al.
Ryan Smith et al.
Delirium is a prevalent neuropsychiatric syndrome during critical illness and is associated with prolonged hospitalization, increased mortality, and post-ICU cognitive decline. It is hypothesized to result from systemic inflammation, disrup...