Low PTGDS Expression Facilitates HNSCC by Suppressing Programmed Cell Death and Reducing B Cell-Mediated Immune Responses [0.03%]
PTGDS低表达通过抑制程序性细胞死亡和减少B细胞介导的免疫反应促进头颈鳞癌发展
Dan Tao,Yuan Zhong,Haoran Zhu et al.
Dan Tao et al.
Head and neck squamous cell carcinoma (HNSCC) constitutes a significant global disease burden. Evasion of programmed cell death (PCD) is a hallmark of HNSCC progression. Cancer-associated fibroblasts (CAFs) are a major cellular component of...
Hsa_circ_0000313/miR-1224-3p/MKNK2 Axis Modulates CD4+ T Cells by Activating p38 MAPK Signaling in Myasthenia Gravis [0.03%]
轴突小结肾上腺素能受体/0000313/微rna-1224-3p轴通过激活p38mapk信号转导在重症肌无力中调节cd4+t细胞
Ying Li,Xiaotong Kong,Hanlu Cai et al.
Ying Li et al.
Background: Myasthenia gravis (MG) is an autoimmune disorder in which circular RNAs (circRNAs) are increasingly implicated, with growing evidence supporting their critical role in autoimmune pathogenesis. The role of hsa_...
Neutrophil Percentage-to-Albumin Ratio: Unveiling a New Perspective on Mortality Risk in Intensive Care Unit Asthma Patients-A Retrospective Cohort Study [0.03%]
中性粒细胞百分比至白蛋白比率：从新的视角揭示重症监护室哮喘患者死亡风险的一项回顾性队列研究
Weide Lin,Junfan Chen,Bixia Lin
Weide Lin
Objectives: Asthma remains a prevalent diagnosis among intensive care unit (ICU) admissions, frequently linked to worsened patient outcomes. Therefore, identifying simple and effective indicators to predict the mortality ...
Systemic Inflammation Mediates the Association Between Admission Hyperglycemia and Pulmonary Infection or Prognosis in Acute Ischemic Stroke [0.03%]
入院高血糖与急性缺血性卒中患者肺部感染及预后关系的中介效应分析：系统性炎症在其中介导作用
Xiaojuan Ma,Jinwei Duan,Ye Cheng et al.
Xiaojuan Ma et al.
Background and perspectives: Hyperglycemia frequently occurs after the onset of acute ischemic stroke (AIS) and the distinct effects and mechanisms of long-term or transient hyperglycemia on stroke outcome are incompletel...
Mendelian Randomization Identified SLC2A9 as a Novel cis-eQTL-Mediated Susceptibility Gene in Suppressing Renal Cancer and Its Related Metabolic Mechanisms [0.03%]
孟德尔随机化鉴定出SLC2A9通过介导cis型表达定量性状基因座(eQTL)抑制肾癌及其相关代谢机制为肾癌易感基因
Yi Wang,Yu Song,Hao Ji et al.
Yi Wang et al.
Objective: Mendelian randomization (MR) analysis has currently been widely used in combination with expression quantitative trait loci (eQTLs) or cis-eQTLs for identifying novel drug targets in various diseases. Hence in ...
Secretome From Human Micro-Fragmented Adipose Tissue Affects In Vitro Monocytes/Macrophages Inflammatory Activity by ICAM-1 Expression [0.03%]
人微片段化脂肪组织的分泌组通过ICAM-1表达影响体外单核细胞/巨噬细胞的炎症活性
Valentina Coccè,Eleonora Martegani,Francesca Paino et al.
Valentina Coccè et al.
Micro-fragmented adipose tissue (MFAT) is regarded as one of the simplest and most practical biological preparations for clinical applications in tissue regenerative medicine. The clinical effectiveness of MFAT is attributed to its content ...
ATOJIN: A Natural Products Mixture, Alleviates Atopic Dermatitis in DNCB-Induced NC/Nga Mice [0.03%]
ATOJIN：一种天然产物混合物，可减轻NC/Nga小鼠DNCB诱导的特应性皮炎
Sang-Eun Lee,Kwang-Jin Cho,Min-Woo Kim et al.
Sang-Eun Lee et al.
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder with increasing global prevalence. ATOJIN is a natural product composed of Phellodendron amurense Ruprecht (PAR), Schizonepeta tenuifolia (ST), Sophora flavescens (SF...
Zengwei Chengqi Decoction Reduces Inflammation in Acute Intestinal Obstruction [0.03%]
增液承气汤可减轻急性肠梗阻患者的炎症反应
Ying Gong,Zi-Hua Xuan,Yue Dong et al.
Ying Gong et al.
Objective: This study investigates the therapeutic effects of Zengwei Chengqi Decoction (ZW) on acute intestinal obstruction (AIO), focusing on its ability to alleviate inflammation and reduce associated tissue damage. Ne...
Luteolin Disrupts Keratinocyte-Dendritic Cell Communication in Psoriasis by Targeting Rh Family C Glycoprotein [0.03%]
黄酮类化合物山柰素通过作用Rh家族C糖蛋白干扰银屑病中角质形成细胞与 dendritic cell通讯
Qian Zhang,Yan-Wei Gao,Cheng-Cheng Feng et al.
Qian Zhang et al.
Psoriasis, a chronic inflammatory skin disease, arises from a dysregulated interaction between keratinocytes (KCs) and dendritic cells (DCs). We previously identified Rh family C glycoprotein (RHCG) as a key mediator of KC inflammation and ...
AJUBA: The Master Regulator Bridging EMT and Immune Evasion in Colorectal Cancer [0.03%]
AJUBA：介导结直肠癌上皮间质转化和免疫逃逸的关键调控因子
Wenhui Shen,Minghui Cui,Xiaoqian Liao et al.
Wenhui Shen et al.
Background: Epithelial-mesenchymal transition (EMT) represents a critical process that facilitates metastatic dissemination and immune evasion in colorectal cancer (CRC); however, the molecular factors that connect EMT to...