NLRP3 Inflammasome: A New Target for the Treatment of CVD and Depression Comorbidity [0.03%]
NLRP3炎性小体：心血管疾病和抑郁症共病的新治疗靶点
Chen Chen,Siqi Zhang,Ming Sheng et al.
Chen Chen et al.
Depression and cardiovascular disease (CVD) frequently coexist, significantly impacting patient prognosis and quality of life. Research indicates that inflammatory responses play a crucial role in the pathogenesis of both conditions. The NL...
Mediating Effects of Immunophenotypes on the Causal Relationship of Gut Microbiota and Their Metabolic Pathways With Osteonecrosis: A Mendelian Randomization Analysis [0.03%]
肠道微生物及其代谢途径通过免疫表型介导骨坏死的因果关系：孟德尔随机化分析
Minlong Wang,Yongjiu Meng,Qinrong Shen et al.
Minlong Wang et al.
Background: This study examined the potential causal relationship between gut microbiota and osteonecrosis and analyzed the mediating effects of immunophenotypes to establish evidence-based causal associations. ...
Correction to "Correlation between the Systemic Immunoinflammatory Index and Platelet-Lymphocyte Ratio in Patients with Adenomyosis" [0.03%]
“系统免疫炎症指数与子宫腺肌症患者的血小板淋巴细胞比值间的关联”一文的更正通知
[This corrects the article DOI: 10.1155/2024/9977750.]. Copyright © 2025 Mediators of Inflammation published by John Wiley & Sons Ltd.
Published Erratum
Mediators of inflammation. 2025 Oct 27:2025:9870832. DOI:10.1155/mi/9870832 2025
Targeting Interferon-Gamma (IFN-γ)-Related Signalling Pathways in Inflammatory Bowel Disease: Emerging Inhibitors and Therapeutic Advances [0.03%]
针对炎症性肠病中的干扰素-γ相关信号通路的靶向治疗：新兴抑制剂和治疗进展
Md Mizanur Rahaman,Phurpa Wangchuk,Subir Sarker
Md Mizanur Rahaman
Inflammatory bowel disease (IBD) encompasses a group of chronic and relapsing inflammatory disorders of the gastrointestinal tract, driven by a multifaceted interplay between genetic predisposition, environmental factors and dysregulated im...
Identification and Characterization of Cytokine Genes in Breast Cancer for Predicting Clinical Outcomes [0.03%]
识别并表征乳腺癌中的细胞因子基因以预测临床结果
Zhifen Han,Yi Yuan,Min Hu et al.
Zhifen Han et al.
Breast cancer is a highly heterogeneous disease with diverse clinical outcomes and treatment responses. While traditional molecular subtypes have improved patient stratification, they fail to fully capture the immune heterogeneity that infl...
Integrative Bulk and Single-Cell Transcriptomic Profiling Reveals Oxidative Stress-Related Genes and Potential Therapeutic Targets in Osteoarthritis [0.03%]
整合批量和单细胞转录组分析揭示了骨关节炎中与氧化应激相关的基因和潜在治疗靶点
Jinhui Peng,Jinzhong Chen,Duan Gao et al.
Jinhui Peng et al.
Osteoarthritis (OA) is increasingly recognized as a degenerative joint disease that leads to a serious problem of public health, yet the underlying molecular mechanisms remain incompletely understood. In this study, we integrated bulk and s...
Correction to "Mesenchymal Stem Cell-Derived Exosomes Modulate Chondrocyte Glutamine Metabolism to Alleviate Osteoarthritis Progression" [0.03%]
关于“间充质干细胞来源的外泌体通过调节软骨细胞谷氨酰胺代谢来缓解骨关节炎进展”的订正通知
[This corrects the article DOI: 10.1155/2021/2979124.]. Copyright © 2025 Mediators of Inflammation published by John Wiley & Sons Ltd.
Published Erratum
Mediators of inflammation. 2025 Oct 9:2025:9790328. DOI:10.1155/mi/9790328 2025
Calcitriol Administration Attenuates Acute Lung Injury by Improving Angiopoietin/Tie2 Dysregulation and Alveolar-Capillary Barrier Integrity in a Mouse Model of Ovariectomy Complicated With Sepsis [0.03%]
维生素D3通过改善卵巢切除联合脓毒症小鼠模型中血管生成素/TIE-2失衡和肺泡毛细血管屏障完整性来缓解急性肺损伤
Chiu-Li Yeh,Shang-Ming Tseng,Mei-Pei Huang et al.
Chiu-Li Yeh et al.
Menopause is associated with excessive weight, increased systemic inflammation, and oxidative stress. Menopause with obesity may aggravate the severity of organ damage when complicated with sepsis. This study investigated the impacts of cal...
The Dual Role of Macrophages in MIRI and MI by Immunity and Inflammation: Damage, Repair, Crosstalk, and Therapy [0.03%]
巨噬细胞在免疫炎症介导的心肌缺血再灌注损伤和心肌梗死中的双重作用：损害、修复、对话及治疗
Zhilin Miao,Yamki Leung,Yuqing Fu et al.
Zhilin Miao et al.
The global prevalence of coronary artery disease (CAD) continues to escalate globally. A substantial proportion of CAD patients develop myocardial ischemic injury or myocardial infarction (MI), while reperfusion therapy paradoxically induce...
Identification and Validation of Pyroptosis-Associated Gene Signature in Primary Sjögren's Syndrome [0.03%]
原发性舍格伦综合征中与焦亡相关基因特征的鉴定和验证
Yijun Dai,Hanzhi Chen,Meng Zhou et al.
Yijun Dai et al.
Background: Pyroptosis, a form of programmed cell death, has been implicated in autoimmune diseases (ADs) pathogenesis. However, its role in primary Sjögren's syndrome (pSS) remains unclear. This study aims to identify p...