Circulating Neutrophil-to-Lymphocyte Ratio Predicts Stroke-Associated Infection and Poststroke Fatigue Affecting Long-Term Neurological Outcomes in Stroke Patients [0.03%]
循环性中性粒细胞与淋巴细胞比率可预测卒中相关感染及卒中后疲乏对卒中患者远期神经功能转归的影响
Lei Zuo,Leiyu Geng,Yujia Cao et al.
Lei Zuo et al.
Background: Since peripheral leukocytes may contribute to the pathophysiology of stroke, the aim of this study was to elucidate the relationship between leukocytes and stroke outcomes and identify which leukocyte subtypes most accurately pr...
Inhibition of the Notch Pathway Alleviates Nab-Paclitaxel-Induced Peripheral Neuropathic Pain in Rats by Suppressing HMGB1/Caveolin-1 Signaling in the Spinal Cord [0.03%]
诺尔特信号通路通过抑制脊髓中HMGB1/caveolin-1信号通路缓解纳米白蛋白结合紫杉醇诱导的大鼠外周神经病理性疼痛
Xing Wei,Yaqing Zhou,Li Ma et al.
Xing Wei et al.
Background: Paclitaxel (PTX) is widely used in the clinical treatment of cancer, and peripheral neuropathy is a common adverse side effect of PTX. Diverse mechanisms contribute to the development and maintenance of PTX-induced peripheral ne...
Dynamic and Static Effects of the Systemic Inflammatory Response Index on All-Cause Mortality in Individuals With Atherosclerotic Cardiovascular Disease: Evidence From National Health and Nutrition Examination Survey [0.03%]
系统性炎症反应指数对动脉粥样硬化性心血管疾病患者全因死亡率的动态和静态效应：来自中国健康与营养调查的证据
Chenglin Duan,Yihang Du,Jiafan Chen et al.
Chenglin Duan et al.
Objective: This research focuses on analyzing the link between the systemic inflammatory response index (SIRI) and all-cause mortality in individuals with atherosclerotic cardiovascular disease (ASCVD) . Methods: This research analyzed data...
A Predictive Model for Acute Kidney Injury Based on Leukocyte-Related Indicators in Hepatocellular Carcinoma Patients Admitted to the Intensive Care Unit [0.03%]
基于白细胞相关指标的肝癌患者重症监护病房急性肾损伤预测模型
Xiulan Peng,Yahong Cai,Huan Huang et al.
Xiulan Peng et al.
Background: This study aimed to develop and validate a straightforward clinical risk model utilizing white blood cell (WBC) counts to predict acute kidney injury (AKI) in critically sick patients with hepatocellular carcinoma (HCC). Methods...
Exploring the Relationship Between Immune Cells and Chronic Kidney Disease by Mendelian Randomization, Colocalization Analysis, and SMR [0.03%]
利用孟德尔随机化、共定位分析和SMR探讨免疫细胞与慢性肾脏疾病的关系
Huiling Zhu,Chaofan Qin,Si Cheng et al.
Huiling Zhu et al.
Background: Chronic kidney disease (CKD) impacts millions of individuals annually. Current research suggests that immune factors played a significant role in CKD. However, the potential causal relationship between them remains unclear. Meth...
Correlation of the Expression Profile of Peripheral Leukocyte and Liver Tissue Immune Markers With Serum Liver Injury Indices in Children With Biliary Atresia [0.03%]
儿童胆道闭锁外周白细胞和肝脏组织免疫标志物表达谱与血清肝损伤指标相关性研究
Anna Helmin-Basa,Izabela Kubiszewska,Joanna B Trojanek et al.
Anna Helmin-Basa et al.
The aim of the study was to find associations between the levels of liver injury serum markers and the selected liver, peripheral leukocytes, and plasma immune characteristics in biliary atresia (BA) children. Twenty-five newly diagnosed BA...
The Association Between Sleep Disorder and Female Infertility: A Mediation Analysis of Inflammatory and Oxidative Markers [0.03%]
睡眠障碍与女性不孕之间的关联：炎症和氧化标志物的中介分析
Qiaorui Yang,Jinfu Zhang,Zhenliang Fan
Qiaorui Yang
Background: Sleep disorder in women of reproductive age may contribute to infertility development, but there is a lack of substantial evidence linking sleep disorder to inflammation and oxidative stress, and the subsequent risk of infertili...
Immune Landscape Variation in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Circulation Before and After Plasmapheresis by Single-Cell Transcriptome [0.03%]
单细胞转录组揭示抗中性粒细胞胞浆抗体相关性血管炎血循环在血浆置换前后的免疫图谱变异特点
Youzhou Tang,Qingtai Cao,Jishi Liu et al.
Youzhou Tang et al.
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of autoimmune diseases characterized by inflammation and destruction of small blood vessels. AAV could be fatal if left untreated. Prompt diagnosis and treatm...
1,25-D3 Protects Diabetic Brain Injury Through GLP-1R/PI3K/Akt Pathway by Experimental and Molecular Docking Studies [0.03%]
1,25-D3通过GLP-1R/PI3K/Akt通路保护糖尿病脑损伤的实验和分子对接研究
Ting Song,Bin Wang,Yutian Li et al.
Ting Song et al.
Background: Diabetes can cause an increase in intracellular glucose, leading to neuronal damage and microvascular dysfunction. Neuroprotective agents 1α,25-dihydroxyvitamin D3 (1,25-D3) can reduce neurological complications. The main purpo...
Suyan Yan,Yaqi Zhao,Yuyu Yang et al.
Suyan Yan et al.
Fibrosis leads to structural damage and functional decline and is characterized by an accumulation of fibrous connective tissue and a reduction in parenchymal cells. Because of its extremely poor prognosis, organ fibrosis poses a significan...