Elevation of Inflammatory Cytokines and Proteins after Intra-Articular Ankle Fracture: A Cross-Sectional Study of 47 Ankle Fracture Patients [0.03%]
47例踝部骨折患者的关节内炎性细胞因子和蛋白水平变化:横断面研究
That Minh Pham,Lars Henrik Frich,Kate Lykke Lambertsen et al.
That Minh Pham et al.
Introduction: Intra-articular fractures are the leading etiology for posttraumatic osteoarthritis (PTOA) in the ankle. Elevation of proinflammatory cytokines following intra-articular fracture may lead to synovial catabol...
Ming Chen,Fuquan Wang,Haifa Xia et al.
Ming Chen et al.
MicroRNAs are small noncoding RNAs which regulate gene expression at the posttranscriptional level. miR-155 is encoded by the miR-155 host gene (miR155HG), also known as the noncoding B cell integration cluster (BIC). MicroRNAs are widely e...
COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation [0.03%]
冠状病毒病2019与Toll样受体4:冠状病毒2可能结合并激活Toll样受体4,以增加ACE2的表达,从而促进其进入细胞并导致过度炎症反应
Mohamed M Aboudounya,Richard J Heads
Mohamed M Aboudounya
Causes of mortality from COVID-19 include respiratory failure, heart failure, and sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that recognizes pathogen-associated molecular patterns (PAMPs) including vira...
Changes in Sepsis Biomarkers after Immunosuppressant Administration in Transplant Patients [0.03%]
器官移植患者免疫抑制剂治疗后脓毒症生物标志物的变化
Janka Franeková,Marek Protuš,Eva Kieslichová et al.
Janka Franeková et al.
Sepsis biomarkers change continuously during the postoperative period. We aimed to demonstrate the influence of immunosuppressants after transplantation (Tx) on presepsin, procalcitonin, CRP, white blood cells, and IL-6. A group of 140 pati...
circRNA circ_102049 Implicates in Pancreatic Ductal Adenocarcinoma Progression through Activating CD80 by Targeting miR-455-3p [0.03%]
环状RNA circ_102049通过靶向miR-455-3p激活CD80促进胰腺导管腺癌进展
Jie Zhu,Yong Zhou,Shanshan Zhu et al.
Jie Zhu et al.
Emerging evidence has shown that circular RNAs (circRNAs) and DNA methylation play important roles in the causation and progression of cancers. However, the roles of circRNAs and abnormal methylation genes in the tumorigenesis of pancreatic...
The Relationship between Retinol-Binding Protein 4 and Markers of Inflammation and Thrombogenesis in Children with Kawasaki Disease [0.03%]
视黄醇结合蛋白4与川崎病患儿炎症和血栓形成的标志物之间的关系
Maoling Yang,Haobo Weng,Qiongfei Pei et al.
Maoling Yang et al.
Background: Kawasaki disease (KD) is a self-limited vasculitis with unknown etiologies, and coronary artery lesions (CALs) are the most common and serious complications. Retinol-binding protein 4 (RBP4) has been confirmed...
Exploring the Pivotal Immunomodulatory and Anti-Inflammatory Potentials of Glycyrrhizic and Glycyrrhetinic Acids [0.03%]
甘草酸和甘草次酸的免疫调节和抗炎潜力探索
Seidu A Richard
Seidu A Richard
Licorice extract is a Chinese herbal medication most often used as a demulcent or elixir. The extract usually consists of many components but the key ingredients are glycyrrhizic (GL) and glycyrrhetinic acid (GA). GL and GA function as pote...
Feiyang Cai,Shuxin Jin,Guangjie Chen
Feiyang Cai
CD4+ T cells play a vital role in the adaptive immune system and are involved in the pathogenesis of many diseases, including cancer, autoimmune diseases, and chronic inflammation. As an important mechanism for energy storage, a lot of rese...
Effect of Oral Administration with Lactobacillus plantarum CAM6 Strain on Sows during Gestation-Lactation and the Derived Impact on Their Progeny Performance [0.03%]
饲喂植物乳杆菌CAM6对妊娠哺乳母猪的影响及其对子代生长性能的影响
César Betancur,Yordan Martínez,Guillermo Tellez-Isaias et al.
César Betancur et al.
Background: To evaluate the biological response of the sows and their offspring with oral administration of Lactobacillus plantarum CAM6 in breeding sows, a total of 20 Pietrain breeding sows with three farrowings and the...
lncRNA SNHG14 Plays a Role in Sepsis-Induced Acute Kidney Injury by Regulating miR-93 [0.03%]
长链非编码RNA SNHG14通过调节miR-93参与脓毒症诱导的急性肾损伤
Chuanchuan Shi,Yuqian Zhao,Qi Li et al.
Chuanchuan Shi et al.
Acute kidney injury (AKI) is a common organ injury in sepsis, which leads to poor prognosis. Long noncoding RNA (lncRNA) small nucleolus RNA host gene 14 (SNHG14) was recognized to induce cell injury in LPS-induced acute lung injury and Par...