Association Between Domain-Specific Physical Activity and Novel Inflammatory Biomarkers Among US Adults: Insights From NHANES 2007-2018 [0.03%]
2007至2018年美国成年人特定领域身体活动与新型炎症生物标志物之间的关联：来自NHANES的见解
Xin-Ying Liu,Kai Yao
Xin-Ying Liu
Objectives: The novel inflammatory biomarkers, including systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and neutrophil-to-lymphocyte ratio (NLR), can contribute to predicting the future risk of variou...
Prognostic Significance of the Serum Creatinine Level During the Shock Stage in Severe Burn Patients: A 10-Year Retrospective Study [0.03%]
严重烧伤患者休克期血清肌酐水平的预后意义：一项十年回顾性研究
Wei Zhu,Xiaorong Xie,Ziqin Shu et al.
Wei Zhu et al.
Objective: To evaluate the significance of serum creatinine (Scr) level during the shock stage as a prognostic indicator for 90-day mortality in severe burn patients. Methods: This retrospective cohort study included 224 severe burn patient...
Analysis of the Correlation Between MDS Inflammatory Indicators and Clinical Characteristics: A Comprehensive Analysis [0.03%]
帕金森病炎性指标与临床特征相关分析：全面解读炎症在帕金森病中作用国际多中心合作研究
ZhongLi Hu,Lijia Pei,ZhongTing Hu et al.
ZhongLi Hu et al.
Objective: This study aims to investigate the correlations among the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) at the initial diagnosis of myelodysplastic syndrome (MDS)...
Unraveling the Gut-Liver-Brain Axis: Microbiome, Inflammation, and Emerging Therapeutic Approaches [0.03%]
解开肠-肝-脑轴：微生物组、炎症和新兴治疗策略
Hiral Aghara,Manali Patel,Prashsti Chadha et al.
Hiral Aghara et al.
The gut-liver-brain axis (GLB axis) plays a crucial role in maintaining metabolic, immune, and neurological homeostasis. The gut microbiota influences systemic health through its metabolites, including short-chain fatty acids (SCFAs), bile ...
WTAP Accelerates Exhaustion of CD8+ T Cells and Progression of Hepatocellular Carcinoma by Promoting m6A Modification and Translation of PD1 mRNA [0.03%]
WTAP通过促进PD-1 mRNA的m6A修饰和翻译加速CD8⁺T细胞衰竭和肝癌进展
Rong Li,Shunle Li,Hua Li et al.
Rong Li et al.
The N6-methyladenosine (m6A) methylase WTAP has been identified as a proto-oncogene in multiple cancers, including hepatocellular carcinoma (HCC). Interestingly, although WTAP expression does not differ between normal liver and HCC tissues ...
Inflammatory Markers Mediate the Association Between Cardiovascular Health and Chronic Inflammatory Airway Diseases: A Cross-Sectional Study on the Population Aged 50 Years and Above From NHANES 2013-2018 [0.03%]
炎症标志物介导心血管健康和慢性炎性呼吸道疾病之间关系：来自NHANES（2013年至2018年）的≥50岁人群横断面研究
Zhaoqi Yan,Xiufan Du,Jing Zhang
Zhaoqi Yan
Objective: This cross-sectional study collected data from participants in the National Health and Nutrition Examination Survey (NHANES) from 2013 to 2018, aiming to investigate the association between cardiovascular health (CVH) and chronic...
CCL2 Inhibitor Bindarit Improve Postoperative Cognitive Function by Attenuating Pericyte Loss-Related Blood-Brain Barrier Disruption and Neuroinflammation [0.03%]
CCL2抑制剂Bindarit通过减轻周细胞丢失相关的血脑屏障破坏和神经炎症来改善术后认知功能
Hui Yuan,Bo Lu,Daofan Sun et al.
Hui Yuan et al.
Perioperative neurocognitive disorder (PND) is a common complication in elderly patients undergoing surgery and anesthesia and associated with the impaired recovery. Previous studies have demonstrated that PND was correlated with the pericy...
Bone Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect Articular Cartilage Through Regulating tRF-Gln-TTG-019/UBL3 [0.03%]
骨髓间充质干细胞来源的外泌体通过调控tRF-Gln-TTG-019/UBL3保护关节软骨
Xialin Li,Zheng Huang,Min Shu et al.
Xialin Li et al.
The tRNA-derived fragments (tRFs) are newly discovered noncoding RNAs enriched in extracellular vesicles (EVs). However, the effects of tRFs as biomarkers have not been investigated in cartilage repair. Bone mesenchymal stromal cells (BMSCs...
Immune Regulation and ECM-Related Pathway Enrichment Reveal ATP2A3 as a Prognostic Biomarker for Nonspecific Orbital Inflammation: An Integrated Machine Learning and Mendelian Randomization Analysis [0.03%]
免疫调节和ECM相关通路富集揭示ATP2A3是非特异性眼眶炎症的预后生物标志物：一种整合机器学习和孟德尔随机化分析
Zixuan Wu,Xi Long,Kang Tan et al.
Zixuan Wu et al.
Background: Nonspecific orbital inflammation (NSOI) is a heterogeneous inflammatory disorder of the orbit with an unclear etiology. ATP2A3, a key regulator of calcium homeostasis in the endoplasmic reticulum (ER), may play a pivotal role in...
S100A11 Promotes Acute Pancreatitis by Upregulating Acinar Cell Ferroptosis [0.03%]
S100A11通过上调胰腺外分泌细胞铁死亡促进急性胰腺炎
Huiyun Zhu,Hongxin Sun,Xianzhu Zhou et al.
Huiyun Zhu et al.
Acute pancreatitis (AP) is a common gastrointestinal disease that can cause systemic inflammation and lead to dysfunction of multiple organs. In pancreatitis, ferroptosis promotes disease progression and organ damage by regulating oxidative...