Epistatic interactions can moderate the antigenic effect of substitutions in haemagglutinin of influenza H3N2 virus [0.03%]
上位性相互作用可缓和血凝素中替代物的抗原效应(INFLUENZA A H3N2病毒)
Björn F Koel,David F Burke,Stefan van der Vliet et al.
Björn F Koel et al.
We previously showed that single amino acid substitutions at seven positions in haemagglutinin determined major antigenic change of influenza H3N2 virus. Here, the impact of two such substitutions was tested in 11 representative H3 haemaggl...
Assessment of the function and intergenus-compatibility of Ebola and Lloviu virus proteins [0.03%]
埃博拉病毒和洛维乌病毒蛋白的功能及属间兼容性评估
Lennart Kämper,Lukas Zierke,Marie Luisa Schmidt et al.
Lennart Kämper et al.
Sequences for Lloviu virus (LLOV), a putative novel filovirus, were first identified in Miniopterus schreibersii bats in Spain following a massive bat die-off in 2002, and also recently found in bats in Hungary. However, until now it is unc...
Population dynamics at neuraminidase position 151 of influenza A (H1N1)pdm09 virus in clinical specimens [0.03%]
临床标本中甲型流感（H1N1）pdm09病毒神经氨酸酶第151位点人群动态学分析
Yu-Nong Gong,Kuo-Chien Tsao,Guang-Wu Chen et al.
Yu-Nong Gong et al.
Influenza A virus mutates rapidly, allowing it to escape natural and vaccine-induced immunity. Neuraminidase (NA) is a surface protein capable of cleaving the glycosidic linkages of neuraminic acids to release newly formed virions from infe...
Identification of novel epitopes in serotype O foot-and-mouth disease virus by in vitro immune selection [0.03%]
体外免疫筛选鉴定新型口蹄疫O型病毒表位
Mana Mahapatra,Sasmita Upadhyaya,Satya Parida
Mana Mahapatra
Foot-and-mouth disease virus (FMDV) displays various epitopes on the capsid outer surface. In addition to the five neutralizing antigenic sites, there is evidence of the existence of other, yet unidentified, epitopes that are believed to pl...
Distinct replication and gene expression strategies of the Rice Stripe virus in vector insects and host plants [0.03%]
水稻条纹病毒在介体昆虫和寄主植物中的不同复制及基因表达策略
Wan Zhao,Qianshuo Wang,Zhongtian Xu et al.
Wan Zhao et al.
Persistent propagative plant viruses are usually transmitted between a vector insect and a host plant. To adapt to the two different organisms, viruses may show distinct genomic replication or gene expression patterns. To verify this hypoth...
Novel subgenotype D11 of hepatitis B virus in NaPo County, Guangxi, bordering Vietnam [0.03%]
广西与越南交界的那坡县新型乙肝病毒D11亚基因型病毒感染分子特征及自然人群血清流行病学调查
Chuang-Chuang Ren,Qin-Yan Chen,Xue-Yan Wang et al.
Chuang-Chuang Ren et al.
Hepatitis B virus has been classified into 10 genotypes and 48 subgenotypes worldwide. We found previously, through polymerase chain reaction (PCR) amplification of a sample collected in 2011, that an HBsAg carrier was infected with two gen...
In praise of preprints [0.03%]
论预印本的好处
Norman K Fry,Helina Marshall,Tasha Mellins-Cohen
Norman K Fry
First detection of bovine coronavirus in Yak (Bos grunniens) and a bovine coronavirus genome with a recombinant HE gene [0.03%]
首次报道牛冠状病毒感染牦牛(Bos grunniens)及牛冠状病毒HE基因重组的新血清型
Qifu He,Zijing Guo,Bin Zhang et al.
Qifu He et al.
The yak (Bosgrunniens) is a unique domestic bovine species that plays an indispensable role for herdsmen in the Qinghai-Tibet Plateau. Here, 336 diarrhoeic samples were collected from yaks on 29 farms in the Qinghai-Tibet Plateau from 2015 ...
Secondary structure of DNA released from purified capsids of human parvovirus B19 under moderate denaturing conditions [0.03%]
适中变性条件下人细小病毒B19纯化壳体释放DNA的二级结构
Bertfried Matz,Bernd Kupfer,René Kallies et al.
Bertfried Matz et al.
Parvovirus B19 (B19V) possesses a linear single-stranded DNA genome of either positive or negative polarity. Due to intramolecular sequence homologies, either strand may theoretically be folded in several alternative ways. Viral DNA, when e...
Han-Ching Wang,Ikuo Hirono,Mary Beth Bacano Maningas et al.
Han-Ching Wang et al.
The family Nimaviridae includes the single species White spot syndrome virus, isolates of which infect a wide range of aquatic crustaceans and cause substantial economic losses. Virions are ellipsoid to bacilliform with a terminal thread-li...