Subhankar Sahu,Rabah Boukherroub,Christophe Ritzenthaler et al.
Subhankar Sahu et al.
Plant virus infections pose a substantial threat to crop quality and productivity, contributing to considerable economic losses in global agriculture annually. Traditionally, laboratories have widely adopted serological techniques, such as ...
Strong immunogenicity and protection against SARS-CoV-2 in hamsters induced by heterologous boost vaccination with an MVA-based COVID-19 vaccine candidate [0.03%]
异源增强型马尔堡病毒载体新冠肺炎疫苗诱导恒河猴和仓鼠产生强免疫反应及保护作用
Sonja Ohrnberger,Christian Meyer Zu Natrup,Sabrina Clever et al.
Sonja Ohrnberger et al.
Over the last decade, heterologous prime-boost vaccination regimens have been established as a promising strategy to enhance immune responses and make optimal use of the advantages of different vaccine platforms. Modified vaccinia virus Ank...
Defective but promising: evaluating the utility of currently available bioinformatic pipelines for detecting defective viral genomes in RNA-Seq data [0.03%]
缺陷但有潜力：评估当前可用的生物信息学管道在RNA测序数据中检测缺陷病毒基因组的实用性
Anthony Taylor,Cristina Rosa,Marco Archetti
Anthony Taylor
Defective viral genomes (DVGs) affect viral dynamics, pathogenicity and evolution, have been found in many in vivo viral infections, and in theory can be detected from sequencing data. We explored the utility of the currently available bioi...
Blair L Strang
Blair L Strang
Vertical transmission of human cytomegalovirus (HCMV) during pregnancy is a major cause of congenital disease. In the absence of robust vaccination strategies, antiviral drug regimens are being developed to inhibit the vertical transmission...
Improved efficacy of an influenza DNA vaccine through high-density microarray patch delivery [0.03%]
通过高密度微针贴片递送改善流感DNA疫苗的有效性
Chloe G Entriken,Kimberley L Bruce,Bridget M Coyne et al.
Chloe G Entriken et al.
Pandemic preparedness requires vaccine platforms that are fast to produce, thermostable and suitable for broad deployment. DNA vaccines are well suited to this task but have historically suffered from poor immunogenicity when delivered by c...
From North to South: transmission dynamics of H1N1pdm09 swine influenza A viruses in Italy [0.03%]
从北到南：意大利猪甲型H1N1流感病毒的传播动力学
Marta Giovanetti,Eleonora Cella,Laura Soliani et al.
Marta Giovanetti et al.
The influenza A H1N1pdm09 virus continues to pose a significant zoonotic threat, with implications for both animal and human health. Italy, which hosts one of the largest swine populations in Europe, is strategically positioned to monitor t...
Wild-type and resistance-breaking strains of tomato spotted wilt virus differentially upregulate the immunosuppressive epoxyoctadecamonoenoic acid biosynthesis of its insect vector, Frankliniella occidentalis [0.03%]
番茄斑枯病病毒野生株系和抗性株系差异诱导其虫媒西花蓟马免疫抑制物质环氧十八碳单烯酸的生物合成
Niayesh Shahmohammadi,Falguni Khan,Donghee Lee et al.
Niayesh Shahmohammadi et al.
Tomato spotted wilt virus (TSWV) is a highly destructive plant pathogen transmitted by thrips, including Frankliniella occidentalis, in a circulative and propagative manner. To counter viral infections, thrips activate antiviral defences th...
Hepatitis B virus is a stealth virus that minimizes proteomic and secretomic changes in primary human hepatocytes [0.03%]
乙型肝炎病毒是一种隐身病毒，可将人 primary human hepatocytes蛋白组和分泌组的改变最小化
Karolína Štaflová,Kamila Clarová,Michal Doležal et al.
Karolína Štaflová et al.
Hepatitis B virus (HBV) is a hepatotropic DNA virus that infects over 250 million people worldwide and causes serious liver diseases. HBV infection can modulate host cellular processes, potentially inducing proteomic changes in hepatocytes....
Immunohistochemical investigation of canine lymph nodes collected during a rabies outbreak in South Africa [0.03%]
南非狂犬病流行期间采集的犬淋巴结免疫组化研究
Redwan Rahmat,Matthijs F Ravensberg,Debby Schipper et al.
Redwan Rahmat et al.
Rabies is a fatal zoonosis that impairs host immune function, yet effects on peripheral lymphoid architecture are poorly defined. During a 2021-2022 rabies virus (RABV) outbreak in South Africa, we collected cervical lymph nodes from 36 rab...
The architecture of membrane structures involved in hepatitis C virus genome replication revealed under close-to-native conditions by cryo-electron tomography [0.03%]
基于低温电子断层扫描的丙型肝炎病毒基因组复制膜结构体系的原位架构研究
Upasana M Sykora,Thomas J O&#x; Sullivan,Yehuda Halfon et al.
Upasana M Sykora et al.
Hepatitis C virus (HCV) infection induces extensive rearrangements of host cytoplasmic membranes, leading to the formation of multiple membranous structures that facilitate RNA replication. Current knowledge of these membranous structures h...