Evolutionary and molecular characteristics of high-Shannon entropy codons in VP1 of Coxsackievirus A6 [0.03%]
柯萨奇病毒A6型VP1高香农熵密码子的分子与进化特征分析
Han Mo,Hui Li,Liu Yi et al.
Han Mo et al.
Coxsackievirus A6 (CVA6) has emerged as a predominant global pathogen of hand, foot and mouth disease, yet its evolutionary and molecular characteristics remain poorly understood. This study integrated 10 year molecular surveillance data fr...
Quantitation of cytopathic honey bee viruses using the viral plaque assay method [0.03%]
定量测定蜂疮病相关蜜蜂病毒的噬斑检测法
Alexander McMenamin,Michael Goblirsch
Alexander McMenamin
Viral pathogens are highly prevalent threats to our pollination workforce. Basic virological techniques for ascertaining infection intensity and quantifying infectious viral particles lag behind the research interest in pollinator-associate...
Tymoviruses partition selection using overlapping genes to allow their replication genes and their movement protein gene to evolve independently [0.03%]
噬菌体 tymovirus 利用重叠基因进行分区选择以使其复制基因和运动蛋白基因独立进化
A J Gibbs,M J Gibbs,H M Gibbs et al.
A J Gibbs et al.
Viral populations evolve as 'negative selection' removes mutants with harmful changes and 'positive selection' preserves mutants with advantageous changes. How do viruses with small genomes, like tymoviruses, resist mutational changes to th...
Characterization of bovine-derived H5N1 viruses expressing fluorescent and luminescent reporter proteins [0.03%]
表达荧光和发光报告蛋白的牛源H5N1病毒的特征分析
Mohammed Nooruzzaman,Pablo Sebastian Britto de Oliveira,Chen Feng et al.
Mohammed Nooruzzaman et al.
Highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses present a broad host range, with recent spillover and sustained transmission in dairy cattle reported in the USA. Replication-competent reporter viruses are critical tools that e...
Human pegivirus, Toscana virus and herpesviruses identified in cerebrospinal fluid from adults with unexplained neurologic disease, Spain, 2022-2023 [0.03%]
西班牙成人未解释神经系统疾病的脑脊液中鉴定出人peg病毒、托斯卡纳病毒和疱疹病毒,2022至2023年
Ana Donoso,Ana Belén Pérez,Marcos Lopez-Dosil et al.
Ana Donoso et al.
Viral central nervous system (CNS) infections in adults frequently remain unresolved after routine diagnostic testing. We applied probe-based viral metagenomic next-generation sequencing (vmNGS) to cerebrospinal fluid samples from adults wi...
Multicenter Study
The Journal of general virology. 2026 Jul;107(7):002302. DOI:10.1099/jgv.0.002302 2026
Data mining reveals the diversity of prophage endolysins targeting pathogenic enterococci [0.03%]
数据挖掘揭示了针对致病性肠球菌的噬菌体溶菌酶的多样性
Finn ODea,Andrew Kinsella,Brooks J Rady et al.
Finn ODea et al.
Antimicrobial resistance poses a critical global health threat, with enterococci among the leading contributors due to their intrinsic and acquired resistance to antibiotics. Clinically relevant species, including Enterococcus faecalis and ...
Endolysosomal two-pore channels regulate a conserved entry pathway for enteroviruses [0.03%]
内溶酶体两孔通道调节肠道病毒的保守入侵途径
Ta-Chou Weng,Bang-Yan Hsu,Tung-Heng Wu et al.
Ta-Chou Weng et al.
Enteroviruses are significant human pathogens for which there are currently no effective antiviral therapies available. Two-pore channels (TPCs) are endolysosomal cation channels activated by nicotinic acid adenine dinucleotide phosphate (N...
Bovine α-herpesvirus 1 replication and immediate early transcription unit 1 promoter are jointly stimulated by glucocorticoid receptor and DNA-dependent ATPases [0.03%]
糖皮质激素受体和DNA依赖性ATP酶共同刺激牛α疱疹病毒1复制及即时早期转录区1启动子
Fouad S El-Mayet,Mike St Clair,Brooke Costello et al.
Fouad S El-Mayet et al.
Bovine α-herpesvirus 1 (BoHV-1) is a significant viral pathogen in cattle and cofactor of bovine respiratory disease (BRD), a polymicrobial disease. Annually, BRD directly costs the U.S. cattle industry ~$1 billion. Following acute infecti...
Yutaro Neriya,Laura Miozzi,Anna Maria Vaira et al.
Yutaro Neriya et al.
Konkoviridae is a family of negative-sense RNA viruses with genomes of 8.7-10.6 kb that have been associated with plants. Virions are filamentous in the shape of kinked circles. The konkovirus genome consists of three or four segments with ...
Variability and population structure of watermelon mosaic virus in zucchini crops in Poland [0.03%]
波兰黄瓜作物中西瓜花叶病毒的变异性和种群结构
Daria Budzyńska,Julia Minicka,Aleksandra Zarzyńska-Nowak et al.
Daria Budzyńska et al.
Watermelon mosaic virus (species Potyvirus citrulli, WMV) poses a significant threat to various cucurbit species worldwide. In Poland, the virus has been consistently recorded in Cucurbita pepo var. giromontiina crops since 2008. To analyse...