Molecular analyses of G3A/G3B and G14 equine group A rotaviruses detected between 2012 and 2018 in Japan [0.03%]
日本2012-2018年间鉴定的G3A/G3B和G14血清群轮状病毒的分子分析
Manabu Nemoto,Hidekazu Niwa,Satoshi Murakami et al.
Manabu Nemoto et al.
Equine group A rotaviruses (RVAs) cause diarrhoea in foals. We investigated the G genotypes of 360 RVA-positive samples obtained from diarrhoeic foals between 2012 and 2018 in the Hidaka district of Hokkaido, Japan, through sequence analysi...
A heterologous prime-boost strategy for immunization against Dengue virus combining the Tetra DIIIC subunit vaccine candidate with the TV005 live-attenuated tetravalent vaccine [0.03%]
结合Tetra DIIIC亚单位疫苗和TV005减毒四价活病毒疫苗的异源序贯免疫策略对登革病毒进行免疫防护
Iris Valdés,Alienys Izquierdo,Karem Cobas et al.
Iris Valdés et al.
The development of live-attenuated vaccines against Dengue virus (DENV) has been problematic. Dengvaxia, licensed in several countries where DENV is endemic, has shown low efficacy profiles and there are safety concerns prohibiting its admi...
Infection of human pegivirus 2 (HPgV-2) is associated with hepatitis C virus but not hepatitis B virus infection in people who inject drugs [0.03%]
人类 Peg病毒2型感染与注射毒品者的丙型肝炎病毒感染相关，但与乙型肝炎病毒感染无关
Jingwei Shui,Wenpei Liu,Yuanhao Liang et al.
Jingwei Shui et al.
We evaluated the association between human pegivirus-2 (HPgV-2) infection and hepatitis C virus (HCV)/hepatitis B virus (HBV) co-infection in 745 plasma samples collected from HCV-positive but human immunodeficiency virus type one (HIV-1)-n...
RNA-seq analysis in equine papillomavirus type 2-positive carcinomas identifies affected pathways and potential cancer markers as well as viral gene expression and splicing events [0.03%]
马传染性乳头状瘤病毒2型阳性肿瘤的RNA测序分析发现了受影响的通路和潜在的癌症标志物以及病毒基因表达和剪接事件
Anna Sophie Ramsauer,Jakub Kubacki,Claude Favrot et al.
Anna Sophie Ramsauer et al.
Equine papillomavirus type 2 (EcPV2) was discovered only recently, but it is found consistently in the context of genital squamous cell carcinomas (SCCs). Since neither cell cultures nor animal models exist, the characterization of this pot...
Mutations in PB2 and HA enhanced pathogenicity of H4N6 avian influenza virus in mice [0.03%]
PB2和HA基因突变可增强H4N6禽流感病毒的致病性
Guanlong Xu,Fang Wang,Qiuchen Li et al.
Guanlong Xu et al.
The H4 subtype avian influenza virus (AIV) continues to circulate in both wild birds and poultry, and occasionally infects mammals (e.g. pigs). H4-specific antibodies have also been detected in poultry farm workers, which suggests that H4 A...
Diverse novel phleboviruses in sandflies from the Panama Canal area, Central Panama [0.03%]
巴拿马中部巴拿马运河区域沙蝇中的新型布尼亚病毒多样化
Marco Marklewitz,Larissa C Dutari,Sofia Paraskevopoulou et al.
Marco Marklewitz et al.
The genus Phlebovirus (order Bunyavirales, family Phenuiviridae) comprises 57 viruses that are grouped into nine species-complexes. Sandfly-transmitted phleboviruses are found in Europe, Africa and the Americas and are responsible for febri...
The Ntail region of nucleocapsid protein is associated with the pathogenicity of pigeon paramyxovirus type 1 in chickens [0.03%]
鸽子副黏病毒1型核衣壳蛋白N尾区与鸡致病性的关联研究
Yang Song,Yu Pei,Yan-Ling Yang et al.
Yang Song et al.
The nucleoprotein (NP) of pigeon paramyxovirus type 1 (PPMV-1) and other paramyxoviruses plays an important role in virus proliferation. A previous study found that NP is associated with the low pathogenicity of PPMV-1 strains in chickens. ...
Anle138b prevents PrP plaque accumulation in Tg(PrP-A116V) mice but does not mitigate clinical disease [0.03%]
安莱138b可防止Tg（PrP-A116V）小鼠中PrP斑块积累，但不能缓解临床症状
Kefeng Qin,Lili Zhao,Ani Solanki et al.
Kefeng Qin et al.
Anle138b is an anti-aggregating compound previously shown to delay the onset of scrapie, a transmissible prion disease, although its in vivo efficacy against other prion disease subtypes has not been fully assessed. TgGSS mice that model Ge...
Jens H Kuhn,Gaya K Amarasinghe,Christopher F Basler et al.
Jens H Kuhn et al.
Members of the family Filoviridae produce variously shaped, often filamentous, enveloped virions containing linear non-segmented, negative-sense RNA genomes of 15-19 kb. Several filoviruses (e.g., Ebola virus) are pathogenic for humans and ...
Wheat streak mosaic virus alters the transcriptome of its vector, wheat curl mite (Aceria tosichella Keifer), to enhance mite development and population expansion [0.03%]
小麦卷叶螨(Aceria tosichella)受小麦条纹花叶病毒(WSMV)调控的转录组变化可增强其发育并促进种群扩张
Adarsh K Gupta,Erin D Scully,Nathan A Palmer et al.
Adarsh K Gupta et al.
Wheat streak mosaic virus (WSMV; genus Tritimovirus; family Potyviridae) is an economically important wheat virus that is transmitted by the wheat curl mite (WCM; Aceria tosichella Keifer) in a persistent manner. Virus-vector coevolution ma...