Long-term culture of human lung adenocarcinoma A549 cells enhances the replication of human influenza A viruses [0.03%]
人肺癌腺癌A549细胞的长期培养增强了人类流感A病毒的复制能力
Michiko Ujie,Kosuke Takada,Maki Kiso et al.
Michiko Ujie et al.
Long-term culture of the human lung adenocarcinoma cell line A549 promotes the differentiation of these cells toward an alveolar type II cell phenotype. Here, we evaluated the susceptibility of long-term cultured A549 cells to human influen...
Detection and characterization of a novel bat-borne coronavirus in Singapore using multiple molecular approaches [0.03%]
采用多种分子方法在新加坡检测并表征一种新型蝙蝠冠状病毒
Xiao Fang Lim,Chengfa Benjamin Lee,Sarah Marie Pascoe et al.
Xiao Fang Lim et al.
Bats are important reservoirs and vectors in the transmission of emerging infectious diseases. Many highly pathogenic viruses such as SARS-CoV and rabies-related lyssaviruses have crossed species barriers to infect humans and other animals....
RNA processing bodies are disassembled during Old World alphavirus infection [0.03%]
旧大陆病毒属感染期间RNA加工体解聚
Lifeng Liu,Eva Weiss,Marc D Panas et al.
Lifeng Liu et al.
RNA processing bodies (P-bodies) are non-membranous cytoplasmic aggregates of mRNA and proteins involved in mRNA decay and translation repression. P-bodies actively respond to environmental stresses, associated with another type of RNA gran...
Yukiyo Sato,Naoyuki Miyazaki,Satoko Kanematsu et al.
Yukiyo Sato et al.
Megabirnaviridae is a family of non-enveloped spherical viruses with dsRNA genomes of two linear segments, each of 7.2-8.9 kbp, comprising 16.1 kbp in total. The genus Megabirnavirus includes the species Rosellinia necatrix megabirnavirus 1...
Mohammad Hajizadeh,Adrian J Gibbs,Fahimeh Amirnia et al.
Mohammad Hajizadeh et al.
The 206 complete genomic sequences of Plum pox virus in GenBank (January 2019) were downloaded. Their main open reading frames (ORF)s were compared by phylogenetic and population genetic methods. All fell into the nine previously recognized...
Henry M Kariithi,Just M Vlak,Johannes A Jehle et al.
Henry M Kariithi et al.
Hytrosaviridae is a family of large, rod-shaped, enveloped entomopathogenic viruses with dsDNA genomes of 120-190 kbp. Hytrosaviruses (also known as salivary gland hypertrophy viruses) primarily replicate in the salivary glands of adult dip...
Henry M Kariithi,Just M Vlak,Johannes A Jehle et al.
Henry M Kariithi et al.
Hytrosaviridae is a family of large, rod-shaped, enveloped entomopathogenic viruses with dsDNA genomes of 120-190 kbp. Hytrosaviruses (also known as salivary gland hypertrophy viruses) primarily replicate in the salivary glands of adult dip...
Identification and characterization of the 285L and K145R proteins of African swine fever virus [0.03%]
非洲猪瘟病毒285L和K145R蛋白的鉴定与表征
Alexandra Hübner,Catharina Keßler,Katrin Pannhorst et al.
Alexandra Hübner et al.
African swine fever (ASF) is a lethal disease of domestic pigs and wild boar, against which no vaccines are available to date. The large dsDNA genome of African swine fever virus (ASFV) contains up to 167 ORFs predicted to encode proteins. ...
Detection and molecular characterization of bovine leukemia virus in various regions of Iran [0.03%]
伊朗不同地区牛白血病病毒的检测及分子特征分析
Monireh Kazemimanesh,Omid Madadgar,Falko Steinbach et al.
Monireh Kazemimanesh et al.
Purpose. Bovine leukemia virus (BLV) infects cattle worldwide, imposing an economic impact on the dairy cattle industry. The purpose of this study was to evaluate the molecular epidemiology of BLV in Iran.Methodology. Blood samples taken fr...
Biological properties of influenza A virus mutants with amino acid substitutions in the HA2 glycoprotein of the HA1/HA2 interaction region [0.03%]
流感A病毒在HA1/HA2相互作用区的HA2糖蛋白上具有氨基酸替代的突变体的生物学特性
L Jakubcová,M Vozárová,J Hollý et al.
L Jakubcová et al.
Influenza A viruses (IAVs) enter into cells by receptor-dependent endocytosis. Subsequently, conformational changes of haemagglutinin are triggered by low environmental pH and the N terminus of HA2 glycoprotein (gp) is inserted into the end...